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Neuropsychiatric Symptoms and Psychotropic Medication Use Following SARS-Cov-2 Infection Among Elderly Residents in Long-Term Care Facilities

Author(s): Cruz-Santiago D; Meng X; Canac-Marquis M; Sengupta A; Brassard JP; Pavey E; Girouard H; Vinh DC; Gouin JP;

Background: SARS-CoV-2 infection can lead to persistent post-acute neuropsychiatric symptoms. Older adults with multimorbidity may be at increased risk of post-acute symptoms after COVID-19. The goals of the present study were to assess the associations of SARS-CoV-2 infection with neuropsychiatr ...

Article GUID: 40051588


Adverse Childhood Experiences Influence Longitudinal Changes in Leptin But Not Adiponectin

Author(s): Matovic S; Rummel C; Neumann E; McGrath J; Gouin JP;

Objective: Adverse childhood experiences (ACEs) are associated with a greater risk of obesity and cardiometabolic disease. Adipokines, including leptin and adiponectin, play vital roles in biological processes linked to obesity and cardiometabolic risk. The adiponectin/leptin ratio may represent a marker of impaired hormonal regulation of adipose tissue. ...

Article GUID: 39909010


Association between aggression and ADHD polygenic scores and school-age aggression: the mediating role of preschool externalizing behaviors and adverse experiences

Author(s): Bouliane M; Boivin M; Kretschmer T; Lafreniere B; Paquin S; Tremblay R; Côté S; Gouin JP; Andlauer TFM; Petitclerc A; Ouellet-Morin I;

Individual differences in physical aggression (PA) are largely heritable. However, it remains unclear how genetic propensity for aggression manifests early in life and relates to school-age PA. Preschool externalizing behavior problems (EXT) and adverse experiences are known predictors of school- ...

Article GUID: 39907790


Cognitive-behavioural therapy for insomnia mechanism of action: Exploring the homeostatic K-complex involvement

Author(s): Sforza M; Morin CM; Dang-Vu TT; Pomares FB; Perrault AA; Gouin JP; Bušková J; Janku K; Vgontzas A; Fernandez-Mendoza J; Bastien CH; Riemann D; Baglioni C; Carollo G; Casoni F; Zucconi M; Castronovo V; Galbiati A; Ferini-Strambi L;

Investigating the mechanisms of action of cognitive-behavioural therapy for insomnia (CBT-I), the first-line treatment for chronic insomnia disorder (ID), can contribute to the overall understanding of insomnia and its treatment. To date, no study has examined the relationship between K-complexes ...

Article GUID: 39739397


Prediction of depressive symptoms in young adults by polygenic score and childhood maltreatment: Results from a population-based birth cohort

Author(s): Scardera S; Geoffroy MC; Langevin R; Perret LC; Collin-Vézina D; Voronin I; Gouin JP; Meng X; Boivin M; Ouellet-Morin I;

Childhood maltreatment is linked with later depressive symptoms, but not every maltreated child will experience symptoms later in life. Therefore, we investigate whether genetic predisposition for depression (i.e., polygenic score for depression, PGSDEP) modifies the association between maltreatm ...

Article GUID: 39465601


Couples-based health behavior change interventions: A relationship science perspective on the unique opportunities and challenges to improve dyadic health

Author(s): Gouin JP; Dymarski M;

Epidemiological studies indicate that better marital quality is associated with less morbidity and premature mortality. A number of interpersonal processes related to marital quality are also associated with health-relevant surrogate biomarkers across different physiological systems. Despite these replicated correlational findings, few interventions have ...

Article GUID: 39155951


Predicting response to stepped-care cognitive behavioral therapy for insomnia using pre-treatment heart rate variability in cancer patients

Author(s): Garneau J; Savard J; Dang-Vu TT; Gouin JP;

Objective: This study examined whether high frequency heart-rate variability (HF-HRV) and HF-HRV reactivity to worry moderate response to cognitive behavioural therapy for insomnia (CBT-I) within both a standard and stepped-care framework among cancer patients with comorbid insomnia. Biomarkers such as HF-HRV may predict response to CBT-I, a finding which ...

Article GUID: 38991424


Changes in social functioning and circulating oxytocin and vasopressin following the migration to a new country

Author(s): Gouin JP; Pournajafi-Nazarloo H; Carter CS;

Prior studies have reported associations between plasma oxytocin and vasopressin and markers of social functioning. However, because most human studies have used cross-sectional designs, it is unclear whether plasma oxytocin and vasopressin influences social functioning or whether social functioning modulates the production and peripheral release of these ...

Article GUID: 25446216


Sleep spindles predict stress-related increases in sleep disturbances

Author(s): Dang-Vu TT; Salimi A; Boucetta S; Wenzel K; O' Byrne J; Brandewinder M; Berthomier C; Gouin JP;

Background and aim: Predisposing factors place certain individuals at higher risk for insomnia, especially in the presence of precipitating conditions such as stressful life events. Sleep spindles have been shown to play an important role in the preservation of sleep continuity. Lower spindle den ...

Article GUID: 25713529


High-frequency heart rate variability during worry predicts stress-related increases in sleep disturbances

Author(s): Gouin JP; Wenzel K; Boucetta S; O' Byrne J; Salimi A; Dang-Vu TT;

Objective: The aim of this study was to evaluate whether high-frequency heart rate variability (HF-HRV) during waking restfulness and during worry predicts increases in sleep disturbances in response to a stressful life event. Methods: A longitudinal study following up 22 individuals from well-defined periods of lower and higher stress was conducted. HF- ...

Article GUID: 25819418


Poor sleep as a pathophysiological pathway underlying the association between stressful experiences and the diurnal cortisol profile among children and adolescents

Author(s): Ly J; McGrath JJ; Gouin JP;

Recent evidence suggests that poor sleep is a potential pathway underlying the association between stressful experiences and the diurnal cortisol profile. However, existing findings are largely limited to adults. The present study examines whether poor sleep (duration, quality) mediates the relation between stressful experiences and the diurnal cortisol p ...

Article GUID: 25889840


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