Author(s): Husser MC; Pham NP; Law C; Araujo FRB; Martin VJJ; Piekny A;
Endogenous tags have become invaluable tools to visualize and study native proteins in live cells. However, generating human cell lines carrying endogenous tags is difficult due to the low efficiency of homology-directed repair. Recently, an engineered spli ...
Article GUID: 38652106
Author(s): Husser MC; Ozugergin I; Resta T; Martin VJJ; Piekny AJ;
Cytokinesis is required to physically separate the daughter cells at the end of mitosis. This crucial process requires the assembly and ingression of an actomyosin ring, which must occur with high fidelity to avoid aneuploidy and cell fate changes. Most of ...
Article GUID: 36416720
Author(s): Jaunky DB; Larocque K; Husser MC; Liu JT; Forgione P; Piekny A;
We reveal the effects of a new microtubule-destabilizing compound in human cells. C75 has a core thienoisoquinoline scaffold with several functional groups amenable to modification. Previously we found that sub micromolar concentrations of C75 caused cytoto ...
Article GUID: 34880347
Author(s): Husser MC, Vo PQN, Sinha H, Ahmadi F, Shih SCC
ACS Synth Biol. 2018 03 16;7(3):933-944 Authors: Husser MC, Vo PQN, Sinha H, Ahmadi F, Shih SCC
Article GUID: 29516725
Author(s): Moazami E, Perry JM, Soffer G, Husser MC, Shih SCC
Anal Chem. 2019 Apr 16;91(8):5159-5168 Authors: Moazami E, Perry JM, Soffer G, Husser MC, Shih SCC
Article GUID: 30945840
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