Reset filters

Search publications


By keyword
By department

No publications found.

 

A chloromethyl-triazole fluorescent chemosensor for O6-methylguanine DNA methyltransferase

Author(s): Ayan S; Rotaru AM; Kaye EG; Juneau G; Das S; Wilds CJ; Beharry AA;

Fluorescent chemosensors offer a direct means of measuring enzyme activity for cancer diagnosis, predicting drug resistance, and aiding in the discovery of new anticancer drugs. O6-methylguanine DNA methyltransferase (MGMT) is a predictor of resistance towa ...

Article GUID: 38502038


Beyond ribose and phosphate: Selected nucleic acid modifications for structure-function investigations and therapeutic applications

Author(s): Liczner C; Duke K; Juneau G; Egli M; Wilds CJ;

Over the past 25 years, the acceleration of achievements in the development of oligonucleotide-based therapeutics has resulted in numerous new drugs making it to the market for the treatment of various diseases. Oligonucleotides with alterations to their sc ...

Article GUID: 33981365


-   Page 1 / 1   -