Author(s): Akhmetov A; Laurent JM; Gollihar J; Gardner EC; Garge RK; Ellington AD; Kachroo AH; Marcotte EM;

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Article GUID: 38161732

Author(s): Sultana S; Abdullah M; Li J; Hochstrasser M; Kachroo AH;

Yeast and humans share thousands of genes despite a billion years of evolutionary divergence. While many human genes can functionally replace their yeast counterparts, nearly half of the tested shared genes cannot. For example, most yeast proteasome subunit ...

Article GUID: 37364278

Author(s): Abdullah M; Greco BM; Laurent JM; Garge RK; Boutz DR; Vandeloo M; Marcotte EM; Kachroo AH; ...

A major challenge to rationally building multi-gene processes in yeast arises due to the combinatorics of combining all of the individual edits into the same strain. Here, we present a precise and ...

Article GUID: 37323580

Author(s): Kachroo AH; Vandeloo M; Greco BM; Abdullah M;

For decades, budding yeast, a single-cellular eukaryote, has provided remarkable insights into human biology. Yeast and humans share several thousand genes despite morphological and cellular differences and over a billion years of separate evolution. These ...

Article GUID: 35661208

Author(s): Garge RK; Cha HJ; Lee C; Gollihar JD; Kachroo AH; Wallingford JB; Marcotte EM;

Thiabendazole (TBZ) is an FDA-approved benzimidazole widely used for its antifungal and antihelminthic properties. We showed previously that TBZ is also a potent vascular disrupting agent and inhibits angiogenesis at the tissue level by dissociating vascula ...

Article GUID: 34849907

Author(s): Laurent JM, Garge RK, Teufel AI, Wilke CO, Kachroo AH, Marcotte EM

PLoS Biol. 2020 May 18;18(5):e3000627 Authors: Laurent JM, Garge RK, Teufel AI, Wilke CO, Kachroo AH, Marcotte EM

Article GUID: 32421706

Author(s): Akhmetov A, Laurent JM, Gollihar J, Gardner EC, Garge RK, Ellington AD, Kachroo AH, Marcotte EM

Bio Protoc. 2018 Mar 20;8(6): Authors: Akhmetov A, Laurent JM, Gollihar J, Gardner EC, Garge RK, Ellington AD, Kachroo AH, Marcotte EM

Article GUID: 29770349

Author(s): Teufel AI, Johnson MM, Laurent JM, Kachroo AH, Marcotte EM, Wilke CO

Mol Biol Evol. 2019 02 01;36(2):304-314 Authors: Teufel AI, Johnson MM, Laurent JM, Kachroo AH, Marcotte EM, Wilke CO

Article GUID: 30428072