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Emerging Image-Guided Navigation Techniques for Cardiovascular Interventions: A Scoping Review

Author(s): Roshanfar M; Salimi M; Jang SJ; Sinusas AJ; Kim J; Mosadegh B;

Background: Image-guided navigation has revolutionized precision cardiac interventions, yet current technologies face critical limitations in real-time guidance and procedural accuracy. Method: Here, we comprehensively evaluate state-of-the-art imaging modalities, from conventional fluoroscopy to emerging hybrid systems, analyzing their applications acros ...

Article GUID: 40428106


Transcriptome-Wide Off-Target Effects of Steric-Blocking Oligonucleotides

Author(s): Holgersen EM; Gandhi S; Zhou Y; Kim J; Vaz B; Bogojeski J; Bugno M; Shalev Z; Cheung-Ong K; Gonçalves J; O' Hara M; Kron K; Verby M; Sun M; Kakaradov B; Delong A; Merico D; Deshwar AG;

Steric-blocking oligonucleotides (SBOs) are short, single-stranded nucleic acids designed to modulate gene expression by binding to RNA transcripts and blocking access from cellular machinery such as splicing factors. SBOs have the potential to bind to near-complementary sites in the transcriptom ...

Article GUID: 34388351


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