Author(s): Kuzmin E; Baker TM; Van Loo P; Glass L;

In the evolution of species, the karyotype changes with a timescale of tens to hundreds of thousand years. In the development of cancer, the karyotype often is modified in cancerous cells over the lifetime of an individual. Characterizing these changes and ...

Article GUID: 38717409

Author(s): Kuzmin E; Baker TM; Lesluyes T; Monlong J; Abe KT; Coelho PP; Schwartz M; Del Corpo J; Zou D; Morin G; Pacis A; Yang Y; Martinez C; Barber J ...

The basal breast cancer subtype is enriched for triple-negative breast cancer (TNBC) and displays consistent large chromosomal deletions. Here, we characterize evolution and maintenance of chromoso ...

Article GUID: 38517886

Author(s): Pereira V; Kuzmin E;

In a recent Cell Genomics article, Tsouris et al.1 analyze the transcriptomes of a large diallel panel of hybrids from Saccharomyces cerevisiae natural isolates to study cis- and trans-regulatory changes underlying gene expression variation. Vanessa Pereira ...

Article GUID: 38216282

Author(s): Dandage R; Papkov M; Greco BM; Fishman D; Friesen H; Wang K; Styles E; Kraus O; Grys B; Boone C; Andrews B; Parts L; Kuzmin E; ...

Gene duplication is common across the tree of life, including yeast and humans, and contributes to genomic robustness. In this study, we examined changes in the subcellular localization and abundan ...

Article GUID: 38045359

Author(s): Hansen JY; Markello RD; Tuominen L; Nørgaard M; Kuzmin E; Palomero-Gallagher N; Dagher A; Misic B; ...

Neurotransmitter receptors modulate signaling between neurons. Thus, neurotransmitter receptors and transporters play a key role in shaping brain function. Due to the lack of comprehensive neurotra ...

Article GUID: 36209794