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Peripheral inflammation in a Canadian cohort of neurodegenerative conditions: Occurrence, determinants, and impact

Author(s): Seixas-Lima B; Rosa-Neto P; Phillips NA; Borrie M; Roncero CT; Lahiri D; Dori D; Eintracht S; Chertkow H;

Background"Inflammaging" describes chronic low-grade inflammation observed in aging individuals. It may play a major role in neurodegeneration.ObjectiveTo assess blood inflammatory markers in older adults. We hypothesized that elevated inflammation would be found in some cognitively nor ...

Article GUID: 41358624


Basic Science and Pathogenesis

Author(s): Lima BS; Rosa-Neto P; Phillips N; Borrie M; Roncero CT; Lahiri D; Dori D; Chertkow H;

Background: A growing body of research has focused on inflammation as both a potential biomarker and a risk factor for Alzheimer's disease (AD). The cytokine Interleukin-6 (IL-6) is involved in the pathogenesis of inflammatory disorders and in the physiological homeostasis of neural tissue. AD has been associated with increased IL-6 expression in brai ...

Article GUID: 39751468


A person with frontotemporal dementia shows increased metabolic rate across multiple brain regions after a series of tDCS sessions

Author(s): Roncero C; Nikelski J; Soucy JP; Lahiri D; Seixas-Lima B; Chertkow H;

No abstract available

Article GUID: 37182684


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