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Exosome-targeted delivery of METTL14 regulates NFATc1 m6A methylation levels to correct osteoclast-induced bone resorption

Author(s): Yang JG; Sun B; Wang Z; Li X; Gao JH; Qian JJ; Li J; Wei WJ; Zhang P; Wang W;

Osteoporosis has a profound influence on public health. First-line bisphosphonates often cause osteonecrosis of the jaw meanwhile inhibiting osteoclasts. Therefore, it is important to develop effective treatments. The results of this study showed that the i ...

Article GUID: 37957146


Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography

Author(s): Lander AJ; Mercado LD; Li X; Taily IM; Findlay BL; Jin Y; Luk LYP;

Tryptophan is frequently found on the surface of membrane-associated proteins that interact with the lipid membrane. However, because of their multifaceted interactions, it is difficult to pinpoint the structure-activity relationship of each tryptophan resi ...

Article GUID: 37464011


A pH-Responsive phosphoprotein washing fluid for the removal of phenanthrene from contaminated peat moss in the cold region

Author(s): Yue R; An C; Ye Z; Li X; Li Q; Zhang P; Qu Z; Wan S;

Oil pollution is one of the major environmental concerns in the petroleum industry. In this study, a cheap food-grade sodium caseinate (NaCas) was used as a pH-responsive washing fluid in the remediation of phenanthrene (PHE) affected peat moss. The effects ...

Article GUID: 36455665


Screening of novel fungal Carbohydrate Esterase family 1 enzymes identifies three novel dual feruloyl/acetyl xylan esterases

Author(s): Dilokpimol A; Verkerk B; Li X; Bellemare A; Lavallee M; Frommhagen M; Nørmølle Underlin E; Kabel MA; Powlowski J; Tsang A; de Vries RP; ...

Feruloyl esterases (FAEs) and acetyl xylan esterases (AXEs) are important enzymes for plant biomass degradation and are both present in Carbohydrate Esterase family 1 (CE1) of the Carbohydrate-Acti ...

Article GUID: 35187647


Flame-Retardant and Polysulfide-Suppressed Ether-Based Electrolytes for High-Temperature Li-S Batteries

Author(s): He M; Li X; Holmes NG; Li R; Wang J; Yin G; Zuo P; Sun X;

Lithium-sulfur (Li-S) batteries are drawing huge attention as attractive chemical power sources. However, traditional ether-based solvents (DME/DOL) suffer from safety issues at high temperatures and serious parasitic reactions occur between the Li metal an ...

Article GUID: 34370436


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