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Enhancing X-ray Activated Photodynamic Therapy with Supported Lipid Bilayer-Coated Radioluminescent Nanoparticles

Author(s): Bondon N; Mandl GA; Mena-Giraldo P; Ferron Z; Sadeghipour N; DeWolf C; Capobianco JA;

We report the synthesis of supported lipid bilayer (SLB)-coated radioluminescent nanoparticles (RLNPs) possessing a lanthanide-based core for low-dose X-ray activated photodynamic therapy (XPDT). Methylene blue (MB) photosensitizer molecules, incorporated within the SLB, are excited by energy transfer from europium, leading to an enhanced generation of re ...

Article GUID: 41059546


Light-Activated Micromotors in Air Propelled by Thermal Convection

Author(s): Mena-Giraldo P; Mandl GA; Quezada-Novoa V; Garcia-Henao C; Bondon N; Hazlett MJ; Capobianco JA;

Micromotors are an attractive cutting-edge technology that exhibit controllable motion in response to chemical reactions or external stimuli. These nature-inspired materials are widely explored for use in environmental remediation, and drug delivery, other emerging applications. Until now, the mi ...

Article GUID: 40964823


Janus Micromotors for Photophoretic Motion and Photon Upconversion Applications Using a Single Near-Infrared Wavelength

Author(s): Mena-Giraldo P; Kaur M; Maurizio SL; Mandl GA; Capobianco JA;

External stimuli can trigger changes in temperature, concentration, and momentum between micromotors and the medium, causing their propulsion and enabling them to perform different tasks with improved kinetic efficiencies. Light-activated micromotors are attractive systems that achieve improved motion and have the potential for high spatiotemporal control ...

Article GUID: 38197400


Cytotoxicity and Genotoxicity of Azobenzene-Based Polymeric Nanocarriers for Phototriggered Drug Release and Biomedical Applications

Author(s): Londoño-Berrío M; Pérez-Buitrago S; Ortiz-Trujillo IC; Hoyos-Palacio LM; Orozco LY; López L; Zárate-Triviño DG; Capobianco JA; Mena-Giraldo P;

Drug nanoencapsulation increases the availability, pharmacokinetics, and concentration efficiency for therapeutic regimes. Azobenzene light-responsive molecules experience a hydrophobicity change from a polar to an apolar tendency by trans-cis photoisomerization upon UV irradiation. Polymeric pho ...

Article GUID: 35956634


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