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Age of obesity onset affects subcutaneous adipose tissue cellularity differently in the abdominal and femoral region

Author(s): Murphy J; Dera A; Morais JA; Tsoukas MA; Khor N; Sazonova T; Almeida LG; Cooke AB; Daskalopoulou SS; Tam BT; Santosa S; ...

Objective: We aimed to examine the effect of age of obesity onset, sex, and their interaction on abdominal and femoral subcutaneous adipose tissue (SAT) morphology (degree of adipocyte hyperplasia ...

Article GUID: 39045668


Senescence markers in subcutaneous preadipocytes differ in childhood- versus adult-onset obesity before and after weight loss

Author(s): Murphy J; Tam BT; Kirkland JL; Tchkonia T; Giorgadze N; Pirtskhalava T; Tsoukas MA; Morais JA; Santosa S; ...

Objective: The aim of this study was to determine the effect of age of obesity onset on senescence-related markers in abdominal (AB) and femoral (FEM) subcutaneous adipose tissue (SAT) before and a ...

Article GUID: 37194560


Association between rs174537 FADS1 polymorphism and immune cell profiles in abdominal and femoral subcutaneous adipose tissue: an exploratory study in adults with obesity

Author(s): Wang C; Murphy J; Delaney KZ; Khor N; Morais JA; Tsoukas MA; Lowry DE; Mutch DM; Santosa S; ...

Fatty acid desaturase 1 (FADS1) polymorphisms alter fatty acid content in subcutaneous adipose tissue (SAT); however, existing evidence is limited and conflicting regarding the association between ...

Article GUID: 33595419


Sex Affects Regional Variations in Subcutaneous Adipose Tissue T Cells but not Macrophages in Adults with Obesity

Author(s): Murphy J; Delaney KZ; Dam V; Tam BT; Khor N; Tsoukas MA; Morais JA; Santosa S;

Objective: The inflammatory environment in lower-body subcutaneous adipose tissue (SAT) has been largely unexplored. This study aimed to examine the effects of region (upper body vs. lower body) and sex on SAT immune cell profiles in young adults with obesi ...

Article GUID: 33179451


The Association Between Dietary Pattern Adherence, Cognitive Stimulating Lifestyle, and Cognitive Function Among Older Adults From the Quebec Longitudinal Study on Nutrition and Successful Aging

Author(s): Parrott MD; Carmichael PH; Laurin D; Greenwood CE; Anderson ND; Ferland G; Gaudreau P; Belleville S; Morais JA; Kergoat MJ; Fiocco AJ; ...

Objective: This study examined the effect of dietary patterns and engagement in cognitive stimulating lifestyle behaviours on trajectory of global cognition, executive function (EF), and verbal epi ...

Article GUID: 33063101


A reliable, reproducible flow cytometry protocol for immune cell quantification in human adipose tissue.

Author(s): Delaney KZ, Dam V, Murphy J, Morais JA, Denis R, Atlas H, Pescarus R, Garneau PY, Santosa S ...

The ability to accurately identify and quantify immune cell populations within adipose tissue is important in understanding the role of immune cells in metabolic disease risk. Flow cytometry is the ...

Article GUID: 32926866


Acetyl-CoA regulation, OXPHOS integrity and leptin level are different in females with different onsets of obesity.

Author(s): Tam BT, Murphy J, Khor N, Morais JA, Santosa S

Although childhood-onset obesity (CO) and adult-onset obesity (AO) are known to lead to distinctive clinical manifestations and disease risks, the fundamental differences between them are largely unclear. The aim of the current study is to investigate the f ...

Article GUID: 32808657


Sex differences in the relationship between dietary pattern adherence and cognitive function among older adults: findings from the NuAge study.

Author(s): D'Amico D, Parrott MD, Greenwood CE, Ferland G, Gaudreau P, Belleville S, Laurin D, Anderson ND, Kergoat MJ, Morais JA, Presse N, Fiocco AJ,

Nutr J. 2020 Jun 20;19(1):58 Authors: D'Amico D, Parrott MD, Greenwood CE, Ferland G, Gaudreau P, Belleville S, Laurin D, Anderson ND, Kergoat MJ, Morais JA, Presse N, Fiocco AJ

Article GUID: 32563260


Obesity and ageing: Two sides of the same coin.

Author(s): Tam BT, Morais JA, Santosa S

Obes Rev. 2020 Feb 05;: Authors: Tam BT, Morais JA, Santosa S

Article GUID: 32020741


Guidelines for Gait Assessments in the Canadian Consortium on Neurodegeneration in Aging (CCNA).

Author(s): Cullen S, Montero-Odasso M, Bherer L, Almeida Q, Fraser S, Muir-Hunter S, Li K, Liu-Ambrose T, McGibbon CA, McIlroy W, Middleton LE, Sarquis ...

Can Geriatr J. 2018 Jun;21(2):157-165 Authors: Cullen S, Montero-Odasso M, Bherer L, Almeida Q, Fraser S, Muir-Hunter S, Li K, Liu-Ambrose T, McGibbon CA, McIlroy W, Middleton LE, Sarquis-Adamson ...

Article GUID: 29977431


SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment.

Author(s): Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais ...

BMC Geriatr. 2018 04 16;18(1):93 Authors: Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais JA, Pieruccini ...

Article GUID: 29661156


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