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pH-Responsive Degradable Electro-Spun Nanofibers Crosslinked via Boronic Ester Chemistry for Smart Wound Dressings

Author(s): Casillas-Popova SN; Lokuge ND; Andrade-Gagnon B; Chowdhury FR; Skinner CD; Findlay BL; Oh JK; ...

Recent advances in the treatment of chronic wounds have focused on the development of effective strategies for cutting-edge wound dressings based on nanostructured materials, particularly biocompat ...

Article GUID: 38989606


Fabrication of thermo-responsive multicore microcapsules using a facile extrusion process

Author(s): Lavertu JD; Bawa KK; Hrapovic S; Fu D; Oh JK; Hemraz UD;

A process employing extrusion was used to produce multicore microcapsules composed of multiple beads. The inner beads were made from ?-carrageenan (?-c), a thermo-responsive linear sulphated polymer whose gelling temperature ranges at 40-60 °C, depending on ...

Article GUID: 38915334


Design, Synthesis, and Acid-Responsive Disassembly of Shell-Sheddable Block Copolymer Labeled with Benzaldehyde Acetal Junction

Author(s): Andrade-Gagnon B; Casillas-Popova SN; Jazani AM; Oh JK;

Smart nanoassemblies degradable through the cleavage of acid-labile linkages have attracted significant attention because of their biological relevance found in tumor tissues. Despite their high potential to achieve controlled/enhanced drug release, a syste ...

Article GUID: 38499007


Preparation of a Convertible Spacer Containing a Disulfide Group for Versatile Functionalization of Oligonucleotides

Author(s): Pontarelli A; Liu JT; Oh JK; Wilds CJ;

The protocols described in this article provide details regarding the synthesis and characterization of a disulfide containing linker phosphoramidite for terminal functionalization of synthetic oligonucleotides. The linker is first synthesized from 6-mercap ...

Article GUID: 36840706


Dual acting acid-cleavable self-assembling prodrug from hyaluronic acid and ciprofloxacin: A potential system for simultaneously targeting bacterial infections and cancer

Author(s): Ibrahim UH; Devnarain N; Mohammed M; Omolo CA; Gafar MA; Salih M; Pant A; Shunmugam L; Mocktar C; Khan R; Oh JK; Govender T; ...

The incidence and of bacterial infections, and resulting mortality, among cancer patients is growing dramatically, worldwide. Several therapeutics have been reported to have dual anticancer and ant ...

Article GUID: 36150574


Synthesis of a Convertible Linker Containing a Disulfide Group for Oligonucleotide Functionalization

Author(s): Pontarelli A; Liu JT; Movasat H; Ménard S; Oh JK; Wilds CJ;

The synthesis and incorporation of a tosylated phosphoramidite linker containing a disulfide bond is described. Incorporation of the linker into short DNA and RNA oligomers proceeded efficiently using automated solid phase synthesis. Treatment of the suppor ...

Article GUID: 35863757


Perfluorocarbon Nanodroplets for Dual Delivery with Ultrasound/GSH-Responsive Release of Model Drug and Passive Release of Nitric Oxide

Author(s): Choi M; Jazani AM; Oh JK; Noh SM;

Nitric oxide (NO) plays a critical role as an important signaling molecule for a variety of biological functions, particularly inhibiting cell proliferation or killing target pathogens. To deliver active radical NO gaseous molecule whose half-life is a few ...

Article GUID: 35683912


Dynamic and Reprocessable Fluorinated Poly(hindered urea) Network Materials Containing Ionic Liquids to Enhance Triboelectric Performance

Author(s): Nellepalli P; Kim MP; Park J; Noh SM; Ye Z; Jung HW; Ko H; Oh JK;

Triboelectric nanogenerators (TENGs), a newly developed energy harvesting device that converts surrounding environmental mechanical stimuli into electricity, have been significantly explored as an ideal long-term power source for electrical devices. Despite ...

Article GUID: 35385641


Electrospun Upconverting Nanofibrous Hybrids with Smart NIR-Light-Controlled Drug Release for Wound Dressing

Author(s): Huang HY; Skripka A; Zaroubi L; Findlay BL; Vetrone F; Skinner C; Oh JK; Cuccia LA;

Chronic wounds present a high risk of infection due to delayed and incomplete healing, leading to increased health risks and financial burden to health-care systems. Numerous approaches to promote wound healing have been extensively explored, especially the ...

Article GUID: 35019380


Dynamic Covalent Polyurethane Network Materials: Synthesis and Self-healability

Author(s): Nellepalli P; Patel T; Oh JK;

Polyurethane (PU) has not only been widely used in our daily lives, but also extensively explored as an important class of the essential polymers for various applications. In recent years significant efforts have been made on the development of self-healabl ...

Article GUID: 34418209


Designing Ultrasmall Carbon Nanospheres with Tailored Sizes and Textural Properties for High-Rate High-Energy Supercapacitors

Author(s): Liu X; Vadiyar MM; Oh JK; Ye Z;

The present work demonstrates the efficient design of ultrasmall porous carbon nanospheres with tailored sizes (5-40 nm in diameter) and optimized intrasphere textural properties for high-rate high-energy supercapacitor application. The carbon nanospheres a ...

Article GUID: 34229427


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