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Microfluidic Wound-Healing Assay for ECM and Microenvironment Properties on Microglia BV2 Cells Migration

Author(s): Yazdanpanah Moghadam E; Sonenberg N; Packirisamy M;

Microglia cells, as the resident immune cells of the central nervous system (CNS), are highly motile and migratory in development and pathophysiological conditions. During their migration, microglia cells interact with their surroundings based on the variou ...

Article GUID: 36832056


Microfluidics in smart packaging of foods

Author(s): Pou KRJ; Raghavan V; Packirisamy M;

The increasing trend in ensuring safe and quality foods necessitates the monitoring of food products throughout the food supply chain. Food packaging is an indispensable process as it provides various functions such as containment, protection, convenience, ...

Article GUID: 36192908


Gold Nano-Bio-Interaction to Modulate Mechanobiological Responses for Cancer Therapy Applications

Author(s): Sohrabi Kashani A; Larocque K; Piekny A; Packirisamy M;

In the present study, we investigate the mechanobiological responses of human lung cancer that may occur through their interactions with two different types of gold nanoparticles: nanostars and nanospheres. Hyperspectral images of nanoparticle-treated cells ...

Article GUID: 35839330


Microfluidic Platforms for the Isolation and Detection of Exosomes: A Brief Review

Author(s): Raju D; Bathini S; Badilescu S; Ghosh A; Packirisamy M;

Extracellular vesicles (EVs) are a group of communication organelles enclosed by a phospholipid bilayer, secreted by all types of cells. The size of these vesicles ranges from 30 to 1000 nm, and they contain a myriad of compounds such as RNA, DNA, proteins, ...

Article GUID: 35630197


Direct sound printing

Author(s): Habibi M; Foroughi S; Karamzadeh V; Packirisamy M;

Photo- and thermo-activated reactions are dominant in Additive Manufacturing (AM) processes for polymerization or melting/deposition of polymers. However, ultrasound activated sonochemical reactions present a unique way to generate hotspots in cavitation bu ...

Article GUID: 35387993


Arraying of microphotosynthetic power cells for enhanced power output

Author(s): Kuruvinashetti K; Packirisamy M;

Microphotosynthetic power cells (µPSCs) generate power through the exploitation of living photosynthetic microorganisms by harvesting sunlight. The thermodynamic limitations of this process restrict the power output of a single µPSC. Herein, we demonstrate ...

Article GUID: 35359612


Simple, Economical Methods for the Culture of Green Algae for Energy Harvesting from Photosynthesis in a Microfluidic Environment

Author(s): Kuruvinashetti K; Rahimi S; Pakkiriswami S; Packirisamy M;

Ongoing technological advancements continually increase the demand for energy. Among various types of energy harvesting systems, biologically based systems have been an area of increasing interest for the past couple of decades. Such systems provide clean, ...

Article GUID: 34898042


Magnetic particle based liquid biopsy chip for isolation of extracellular vesicles and characterization by gene amplification

Author(s): Bathini S; Pakkiriswami S; Ouellette RJ; Ghosh A; Packirisamy M;

Extracellular vesicles (EVs) are the cell-derived vesicles which play a critical role in cell-to-cell communication, and disease progression. These vesicles contain a myriad of substances like RNA, DNA, proteins, and lipids from their origin cells, offering ...

Article GUID: 34517262


Cancer-Nano-Interaction: From Cellular Uptake to Mechanobiological Responses

Author(s): Sohrabi Kashani A; Packirisamy M;

With the advancement of nanotechnology, the nano-bio-interaction field has emerged. It is essential to enhance our understanding of nano-bio-interaction in different aspects to design nanomedicines and improve their efficacy for therapeutic and diagnostic a ...

Article GUID: 34502495


Optical Fiber Array Sensor for Force Estimation and Localization in TAVI Procedure: Design, Modeling, Analysis and Validation

Author(s): Bandari N; Dargahi J; Packirisamy M;

Transcatheter aortic valve implantation has shown superior clinical outcomes compared to open aortic valve replacement surgery. The loss of the natural sense of touch, inherited from its minimally invasive nature, could lead to misplacement of the valve in ...

Article GUID: 34450813


Using intracellular plasmonics to characterize nanomorphology in human cells.

Author(s): Sohrabi Kashani A, Piekny A, Packirisamy M

Determining the characteristics and localization of nanoparticles inside cells is crucial for nanomedicine design for cancer therapy. Hyperspectral imaging is a fast, straightforward, reliable, and accurate method to study the interactions of nanoparticles ...

Article GUID: 33365137


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