Author(s): Caballero HS; McFall GP; Gee M; MacDonald S; Phillips NA; Fogarty J; Montero-Odasso M; Camicioli R; Dixon RA;

Background: Alzheimer's disease (AD) and Lewy body disease (LBD) are characterized by early and gradual worsening perturbations in speeded cognitive responses. Objective: Using simple and choice reaction time tasks, we compared two indicators of cognitive speed within and across the AD and L ...

Article GUID: 38875040

Author(s): Dumassais S; Pichora-Fuller MK; Guthrie D; Phillips NA; Savundranayagam M; Wittich W;

Background: Dual sensory impairment (DSI), the combination of visual and hearing impairments, is associated with increased risk for age-related cognitive decline and dementia. Administering cognitive tests to individuals with sensory impairment is challenging because most cognitive measures require sufficient hearing and vision. Considering sensory limita ...

Article GUID: 38506649

Author(s): Grunden N; Phillips NA; ;

Subjective cognitive decline (SCD) is characterized by subjective concerns of cognitive change despite test performance within normal range. Although those with SCD are at higher risk for developing further cognitive decline, we still lack methods using objective cognitive measures that reliably distinguish SCD from cognitively normal aging at the group l ...

Article GUID: 38458017

Author(s): Downey R; Gagné N; Mohanathas N; Campos JL; Pichora-Fuller KM; Bherer L; Lussier M; Phillips NA; Wittich W; St-Onge N; Gagné JP; Li K;

Background: Hearing loss predicts cognitive decline and falls risk. It has been argued that degraded hearing makes listening effortful, causing competition for higher-level cognitive resources needed for secondary cognitive or motor tasks. Therefore, executive function training has the potential ...

Article GUID: 37864139

Author(s): Bethell J; Andrew MK; Hothi S; Mick P; Morgan D; O' Connell ME; Phillips NA; Stewart S; Walker JD; Wittich W; McGilton KS;

Objectives: This study tested the association between neuroticism and six cognitive measures, and examined the potential mediating roles of social connection (social isolation and loneliness) among middle-aged and older adults. Methods: This cross-sectional study was a secondary analysis of the ...

Article GUID: 37667914

Author(s): Papadatos Z; Phillips NA;

We examined cognitive domains and brain regions associated with olfactory performance in cognitively unimpaired older adults (CU-OAs) and individuals with or at risk for Alzheimer's Disease (AD). We compared CU-OAs (N = 55), individuals with subjective cognitive decline (SCD, N = 55), mild cognitive impairment (MCI, N = 101), and AD (N = 45) on measur ...

Article GUID: 37146503

Author(s): Giroud N; Pichora-Fuller MK; Mick P; Wittich W; Al-Yawer F; Rehan S; Orange JB; Phillips NA;

Using data from the COMPASS-ND study we investigated associations between hearing loss and hippocampal volume as well as cortical thickness in older adults with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer's dementia (AD). SCD participants with greater pu ...

Article GUID: 36911511

Author(s): Al-Yawer F; Pichora-Fuller MK; Wittich W; Mick P; Giroud N; Rehan S; Phillips NA;

Objectives: Hearing loss (HL) in older adults is associated with a decline in performance on cognitive tasks and the risk of developing dementia. However, very few studies have investigated sex-related effects on these associations. A previous study of cognitively healthy older adults showed an association between HL and lower cognitive performance in fem ...

Article GUID: 36607746

Author(s): Reavis KM; Bisgaard N; Canlon B; Dubno JR; Frisina RD; Hertzano R; Humes LE; Mick P; Phillips NA; Pichora-Fuller MK; Shuster B; Singh G;

There is robust evidence that sex (biological) and gender (behavioral/social) differences influence hearing loss risk and outcomes. These differences are noted for animals and humans-in the occurrence of hearing loss, hearing loss progression, and response to interventions. Nevertheless, many stu ...

Article GUID: 36384870

Author(s): Caballero JA; Auclair Ouellet N; Phillips NA; Pell MD;

Introduction: Parkinson's Disease (PD) commonly affects cognition and communicative functions, including the ability to perceive socially meaningful cues from nonverbal behavior and spoken language (e.g., a speaker's tone of voice). However, we know little about how people with PD use social information to make decisions in daily interactions (e.g ...

Article GUID: 35997248

Author(s): Guthrie DM; Williams N; Campos J; Mick P; Orange JB; Pichora-Fuller MK; Savundranayagam MY; Wittich W; Phillips NA;

Vision and hearing impairments are highly prevalent in adults 65 years of age and older. There is a need to understand their association with multiple health-related outcomes. We analyzed data from the Resident Assessment Instrument for Home Care (RAI-HC). Home care clients were followed for up t ...

Article GUID: 35859361