Author(s): Silva NCBS; Stein RG; Gu Y; Hsu CL; Tam RC; Salluzzi M; McCreary CR; Alkeridy WA; Lam K; MacKay AL; Kolind S; Cossette B; Griffith LE; Hogan DB; McMillan JM; Raina P; Smith EE; Liu-Ambrose T;

Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative agent of COVID-19 and has infected >700 million persons worldwide. Individuals infected with SARS-CoV-2 are at risk for cognitive decline and at higher risk of dementia compared with those diagnosed with oth ...

Article GUID: 41434542

Author(s): Silva NCBS; Balbim GM; Stein RG; Gu Y; Tam RC; Dao E; Alkeridy WA; Kramer AF; Liu-Ambrose T;

Background: Physical activity is associated with higher myelin content in older individuals with cerebral small vessel disease (CSVD), a condition marked by demyelination. However, potential mechanisms underlying these associations remain understudied. High-density lipoprotein (HDL) is involved i ...

Article GUID: 41435075

Author(s): Pieruccini-Faria F; Son S; Liu-Ambrose T; Burhan AM; Almeida QJ; Middleton LE; Li K; Fraser S; Bherer L; Montero-Odasso M;

Background: Mild Cognitive Impairment (MCI) may be associated with the presence of the apolipoprotein E4 allele (APOE4), a genetic factor linked to accelerated cognitive decline. The SYNERGIC trial demonstrated that physical exercise (PE) involving aerobic and resistance training improves global ...

Article GUID: 41435121

Author(s): Borrie MJ; Phillips NA; Best S; Anastasiou-Ventura P; Aydogan T; Beaudoin C; Beuk J; Celotto I; Cole L; Das S; Fogarty J; Fouquet C; Gnassi L; Henri-Bellemare C; Pilon R; Sands J; Stirbu A; Truemner J; Chan S; Tucker A; Gajraj J; Bhangu ...

Background: The Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS-ND) used wide inclusion criteria recruiting participants across the spectrum from normal cognition to cognitive impairment to all types of clinical dementia, including mixed dementia. 1173 participants comprising ...

Article GUID: 41435411

Author(s): Mitchell SW; Chan T; Trudel L; Hosseini SA; Macedo AC; Gonçalves MP; Rahmouni N; Hall BJ; Socualaya KMQ; Therriault J; Servaes S; Bezgin G; Zheng Y; Aumont E; Wang YT; Arias JF; Real APB; Jia WL; Hopewell R; Hsiao C; Soucy JP; Vitali P; ...

Background: Brain and cognitive resilience (BR, CR) reflect the capacity to maintain structural integrity and cognitive function despite pathological tau deposition in Alzheimer's disease (AD). Tau pathology can be characterized in terms of spatial extent of tauopathy (SEOT) or load using sta ...

Article GUID: 41433447

Author(s): Gurve D; Centen AP; Slack PJ; Dang-Vu TT; Belleville S; Anderson ND; Montero-Odasso M; Nygaard HB; Chertkow H; Feldman HH; Brewster PWH; Lim A;

Background: Older adults experience considerable day-to-day variability in cognitive function. We aimed to test the hypothesis that this is in part related to sleep, and determine which EEG sleep features are most important in supporting day to day cognitive resilience. Method: We analyzed data ...

Article GUID: 41434309

Author(s): Biglieri S; Ahmed N; Main S; Tupling OL; Vijayakumar R; Boger J; Daum C; Dupuis S; Koch M; Liu L; Lopez K; Mann J; Martin M; McAiney C; Nasir HJ; Nasir N; Pearce B; Weldrick R; Vanderlinden K; Middleton L;

Exclusion, marginalization and stigma remain common experiences for people living with dementia. Dementia capable communities offer a pathway to support the wellbeing of people living with dementia by creating spaces where people living with dementia and their care partners are supported and empo ...

Article GUID: 41432943

Author(s): Morrison K; Pottier P; Pollo P; Ricolfi L; Williams C; Yang Y; Beillouin D; Cardoso SJ; Ferreira V; Gallagher B; Gan JL; Hao G; Keikha M; Kozlowsky-Suzuki B; Kiran Kumara TM; Latterini F; Leverkus AB; Macartney EL; Manrique SM; Martinig ...

Meta-analysis is commonly a core component of systematic reviews and has become an important method to reconcile conflicting findings, increase statistical power, and chart new research directions. However, poor reporting practices make it challenging to evaluate the validity of meta-analyses. De ...

Article GUID: 41411971

Author(s): Qiu W; Yang G; Cao L; Niu S; Li Y; Fang D; Dong Z; Magnuson JT; Schlenk D; Leung KMY; Zheng Y; Zeng Z; Feng L; Zhang X; Zhang Y; Fan W; Huang T; Ma J; Wu M; Tao S; Zheng C;

Global food trade expansion has enriched diets worldwide but also heightened concerns about contaminant spread. Per- and polyfluoroalkyl substances (PFAS) can persist in the environment for decades, yet their risks through food trade remain unclear. The global median estimated daily intake (EDI) ...

Article GUID: 41411415

Author(s): Spiech C; Câmara GS; Fuhrer J; Penhune V;

The pleasurable urge to move to music, termed "groove," is thought to arise from the tension between top-down metric expectations or predictions and rhythmic complexity. Specifically, groove ratings are highest for moderately complex rhythms, balancing expectation and surprise. To test this, meter and rhythmic complexity need to be manipulated i ...

Article GUID: 41402552

Author(s): Côté M; Kairouz S; Savard AC; Brodeur M;

Objective: This article is one of the first to examine the impact of the COVID-19 pandemic on online gambling (OG) participation and gambling-related problems in relation to living conditions. The latter include whether people reported being in a significant intimate relationship, their living arrangements (alone vs. cohabitation), and whether they lived ...

Article GUID: 41387820