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A digital cognitive behavioural therapy programme for insomnia and anxiety in older adults: feasibility and preliminary efficacy

Author(s): Reyt M; Adoutoro J; Borgetto F; Desrosiers C; Barbaux L; Gong K; Savard J; Grenier S; Dang Vu TT;

Insomnia and anxiety are highly prevalent and often comorbid in older adults. Although cognitive behavioural therapy is the first-line treatment for insomnia, few interventions simultaneously address both conditions. Furthermore, access remains limited by provider availability and high costs. To ...

Article GUID: 42096653


Seroprevalence of Neospora caninum in Camelids of the New and Old World: A Global Systematic Review and Meta-Analysis

Author(s): Mohemmi N; Karamati SA; Miladi R; Khodayari MT; Bashiri H; Faraji R; Falahi S; Jalilian S; Bozorgomid A; Hamzavi Y;

Neospora caninum (protozoa: Apicomplexa) is a major cause of economic losses in bovine production systems due to reproductive failure and abortion in cows. Although there is evidence of camelids being exposed to N. caninum, the importance of these animals in the parasite's life cycle is uncle ...

Article GUID: 42084849


Separation of Time Scales in Weakly Interacting Diffusions

Author(s): Zachary P Adams

We study metastable behaviour in systems of weakly interacting Brownian particles with localised, attractive potentials which are smooth and globally bounded. In this particular setting, numerical evidence suggests that the particles converge on a short time scale to a " droplet state" which is metastable, i.e. persists on a much longer time sca ...

Article GUID: 42077230


Characterization of the Biosurfactant Produced by Indigenous Bacteria from Mature Fine Tailings

Author(s): Shojaei S; Mulligan CN;

Biosurfactants offer a green, sustainable approach to many environmental bioremediations, especially for oil contamination. In this study, the aim is to evaluate the effectiveness of biosurfactants in accelerating hydrocarbon removal from mature fine tailings under anaerobic conditions. The bacteria were isolated from mature fine tailings and tested for b ...

Article GUID: 42072246


A Functional Shape Framework for the Detection of Multiple Sclerosis Using Optical Coherence Tomography Images

Author(s): Tahvilian H; Kafieh R; Ashtari F; Swamy MNS; Ahmad MO;

Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease. Optical coherence tomography (OCT) is a non-invasive imaging technique of the retina. The thickness of the ganglion cell-inner plexiform layer (GCIPL) obtained from an OCT image is a valuable biomarker for monitoring MS. Since the functional shape (F-shape)-based technique has prove ...

Article GUID: 42076512


Microwave Synthesis of CuNi/TiO sub 2 /sub Nanotubes for Enhanced Photocatalytic H sub 2 /sub Generation

Author(s): Yimbila S; Perdomo C; Vo DK; Pérez CJV; Onwubiko V; Nguyen NT;

Microwave-assisted synthesis offers several advantages over conventional methods, including shorter reaction times and more efficient heating in systems containing polar solvents such as water or ethanol. These features can be exploited to prepare and modify active photocatalysts for H2-production reactions, allowing precise tuning of composition and fina ...

Article GUID: 42059823


Neural and cardiorespiratory responses in vocalization and slow breathing: Contrasting brain and autonomic responses

Author(s): Ruiz-Blais S; Bernardi NF; Intartaglia B; Snow S; Lehmann A;

Singing and vocalization practices are reportedly associated with increased relaxation, better emotional regulation, and enhanced social closeness. Here, we investigate the neural underpinnings of such effects and ask whether they are related to processes linked to the vocalization aspect or are a result of modified breathing patterns. Toning is a form of ...

Article GUID: 42054483


Inter- vs Intramolecular Aldehyde-Alkyne-Amine A sup 3 /sup -Reaction in the Solution-Phase Synthesis of a Potent Macrocyclic Azapeptide CD36 Modulator

Author(s): Maarouf-Mesli N; Fonseca JC; Harvey SM; Chauhan PS; Mulumba M; Ahsanullah None; Selka A; Meneksedag Erol D; Chemtob S; Ong H; Polyak F; Lubell WD;

Modern macrocyclic peptides feature unnatural elements that are used to improve the activity and pharmacokinetic properties. Chemistry beyond peptide synthesis must, however, be employed to introduce such elements. Notably, application of the copper-catalyzed aldehyde-alkyne-amine A3-reaction in ...

Article GUID: 42049622


Intervention development to reduce sedentary behaviour among adults: a qualitative investigation using the Behaviour Change Wheel

Author(s): Harsanyi H; Slot N; Parkinson R; Morielli AR; Jeyapalan A; Holmes E; Flynn S; Campbell T; Quan H; Zeng Y; Yang J; Singh S; Vena J; Biddle S; Friedenreich CM; Yang L;

Article GUID: 42015269


Quantitative modeling of nanoplastic accumulation from single-use water bottles: exposure scenarios and tissue concentration estimates

Author(s): Sajedi S; An C;

The widespread use of single-use plastic (SUP) water bottles has raised growing concerns about chronic human exposure to nanoplastics (NPs). This study presents a quantitative assessment of NP accumulation in human tissues resulting from the long-term consumption of SUP water bottles. Using survey-derived consumption data and the Human Exposure and Absorp ...

Article GUID: 42007012


Holistic valorization of microalgal slurry into biofuels via integrated simultaneous saccharification and fermentation using co-immobilized tri-enzymes

Author(s): Ha GS; Basak B; Ahn HJ; Baek G; Hwang JH; Roh HS; Chung WJ; Jeon BH;

The commercial viability of microalgal biorefineries is currently constrained by high energy demands during pretreatment and incomplete biomass valorization arising from cell wall recalcitrance. To overcome these challenges, this study developed a high-efficiency simultaneous saccharification and fermentation (SSF) strategy using an immobilized tri-enzyme ...

Article GUID: 41997248


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