Author(s): Espinosa S; Silva JF; Céspedes S;

A central challenge in hypothesis testing (HT) lies in determining the optimal balance between Type I (false positive) and Type II (non-detection or false negative) error probabilities. Analyzing these errors' exponential rate of convergence, known as e ...

Article GUID: 39056958

Author(s): Jaber K; Avigdor T; Mansilla D; Ho A; Thomas J; Abdallah C; Chabardes S; Hall J; Minotti L; Kahane P; Grova C; Gotman J; Frauscher B; ...

Stereo-electroencephalography (SEEG) is the gold standard to delineate surgical targets in focal drug-resistant epilepsy. SEEG uses electrodes placed directly into the brain to identify the seizure ...

Article GUID: 38897997

Author(s): McComb S; Arbabi-Ghahroudi M; Hay KA; Keller BA; Faulkes S; Rutherford M; Nguyen T; Shepherd A; Wu C; Marcil A; Aubry A; Hussack G; Pinto DM ...

Chimeric antigen receptor (CAR) T cell therapies targeting B cell-restricted antigens CD19, CD20, or CD22 can produce potent clinical responses for some B cell malignancies, but relapse remains com ...

Article GUID: 38596311

Author(s): Dumassais S; Pichora-Fuller MK; Guthrie D; Phillips NA; Savundranayagam M; Wittich W;

Background: Dual sensory impairment (DSI), the combination of visual and hearing impairments, is associated with increased risk for age-related cognitive decline and dementia. Administering cognitive tests to individuals with sensory impairment is challengi ...

Article GUID: 38506649

Author(s): Ayan S; Rotaru AM; Kaye EG; Juneau G; Das S; Wilds CJ; Beharry AA;

Fluorescent chemosensors offer a direct means of measuring enzyme activity for cancer diagnosis, predicting drug resistance, and aiding in the discovery of new anticancer drugs. O6-methylguanine DNA methyltransferase (MGMT) is a predictor of resistance towa ...

Article GUID: 38502038

Author(s): Stewart BM; Joyce MM; Creeggan J; Eccles S; Gerwing MG; Turner SE;

Congenital malformations, conditions, injuries, and illness can lead to long-term physical impairment and disability in nonhuman primates. How individual primates change their behaviors flexibly to compensate for their disabilities can inform our understand ...

Article GUID: 38050800

Author(s): Hankins JS; Brambilla D; Potter MB; Kutlar A; Gibson RW; King AA; Baumann AA; Melvin CL; Gordeuk VR; Hsu LL; Nwosu C; Porter JS; Alberts NM; ...

Hydroxyurea reduces sickle cell disease (SCD) complications, but medication adherence is low. We tested two mobile health (mHealth) interventions targeting determinants of low adherence among patie ...

Article GUID: 37738155

Author(s): Vaz S; Manes S; Khattar G; Mendes M; Silveira L; Mendes E; de Morais Rodrigues E; Gama-Maia D; Lorini ML; Macedo M; Paiva PC; ...

Anthropic stressors are among the greatest concerns in nature conservation. Among these, deforestation and urban expansion are major drivers of habitat loss, which is a major threat to biodiversity ...

Article GUID: 37543317

Author(s): Dokumaci A; Bessette-Viens R; Goberdhan N; Lucas S; Mazowita A; Stainton J;

In this article, we present six autoethnographies of lives marked by crisis that reflect on the issues of access, very broadly defined, that the COVID 19 pandemic has raised or redefined for each of us. As the time of crisis has made access concerns more an ...

Article GUID: 37461398

Author(s): van Allen Z; Bacon SL; Bernard P; Brown H; Desroches S; Kastner M; Lavoie KL; Marques MM; McCleary N; Straus S; Taljaard M; Thavorn K; Tomas ...

Background: Health behaviors such as physical inactivity, unhealthy eating, smoking tobacco, and alcohol use are each leading risk factors for non-communicable chronic disease. Better understanding ...

Article GUID: 37155331

Author(s): Alberga AS; Edache IY; Sigal RJ; von Ranson KM; Russell-Mayhew S; Kenny GP; Doucette S; Prud' homme D; Hadjiyannakis S; Cameron JD; Gol ...

Background: There are well-recognized benefits of behavioral interventions that include exercise for children and adolescents with obesity. However, such behavioral weight management programs may p ...

Article GUID: 37034563