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Age of obesity onset affects subcutaneous adipose tissue cellularity differently in the abdominal and femoral region

Author(s): Murphy J; Dera A; Morais JA; Tsoukas MA; Khor N; Sazonova T; Almeida LG; Cooke AB; Daskalopoulou SS; Tam BT; Santosa S; ...

Objective: We aimed to examine the effect of age of obesity onset, sex, and their interaction on abdominal and femoral subcutaneous adipose tissue (SAT) morphology (degree of adipocyte hyperplasia ...

Article GUID: 39045668


Compensatory health motivations and behaviors scale: Development, evaluation, psychometric properties and a preliminary validation

Author(s): Sedemedes K; Knäuper B; Sadikaj G; Yuan TY; Wrosch C; Santosa S; Alberga AS; Kakinami L;

The "Compensatory Health Beliefs" scale assesses the degree to which one believes that unhealthy behaviours can be compensated through healthier ones. However, no validated scale to assess compensatory weight-related behaviors exists. The study's object ...

Article GUID: 37804879


Senescence markers in subcutaneous preadipocytes differ in childhood- versus adult-onset obesity before and after weight loss

Author(s): Murphy J; Tam BT; Kirkland JL; Tchkonia T; Giorgadze N; Pirtskhalava T; Tsoukas MA; Morais JA; Santosa S; ...

Objective: The aim of this study was to determine the effect of age of obesity onset on senescence-related markers in abdominal (AB) and femoral (FEM) subcutaneous adipose tissue (SAT) before and a ...

Article GUID: 37194560


Understanding the impact of radical changes in diet and the gut microbiota on brain function and structure: rationale and design of the EMBRACE study

Author(s): Ben-Porat T; Alberga A; Audet MC; Belleville S; Cohen TR; Garneau PY; Lavoie KL; Marion P; Mellah S; Pescarus R; Rahme E; Santosa S; Studer ...

Background: Bariatric surgery leads to profound changes in gut microbiota and dietary patterns, both of which may interact to impact gut-brain communication. Though cognitive function improves post ...

Article GUID: 37088645


Body-composition phenotypes and their associations with cardiometabolic risks and health behaviours in a representative general US sample

Author(s): Kakinami L; Plummer S; Cohen TR; Santosa S; Murphy J;

Body mass index is poor at distinguishing between adiposity and muscle. Based on dual energy X-ray absorptiometry data, a diagnostic framework to analyze body composition by categorizing fat- and muscle-mass body composition into four phenotypes has been pr ...

Article GUID: 36183799


Adipocyte size, adipose tissue fibrosis, macrophage infiltration and disease risk are different in younger and older individuals with childhood versus adulthood onset obesity

Author(s): Turner L; Gauthier MF; Lafortune A; Tchernof A; Santosa S;

Background: The timing of obesity onset and age have been shown to affect the risk of obesity-related comorbidities, although the impact of each of these factors on markers of adipose tissue function remains unclear. Objective: The aim of this study was to ...

Article GUID: 35927468


Editorial: The Effect of Carbohydrate Restriction on Cancer and Metabolic Syndrome

Author(s): Elisia I; Santosa S; Popovich DG; Krystal G;

No abstract

Article GUID: 35237644


Assessing the Contribution of Traditional Foods to Food Security for the Wapekeka First Nation of Canada

Author(s): Robidoux MA; Winnepetonga D; Santosa S; Haman F;

The food security crisis and disproportionately high burden of dietary related disease amongst northern Indigenous populations in Canada continues to be a troubling reality with little sign of improvement. The Government of Canada is responding by developin ...

Article GUID: 34310881


Adiposity and muscle mass phenotyping is not superior to BMI in detecting cardiometabolic risk in a cross-sectional study

Author(s): Kakinami L; Danieles PK; Ajibade K; Santosa S; Murphy J;

Objective: Classifying adiposity based on dual-energy x-ray absorptiometry (DXA) muscle and fat mass phenotypes has been proposed. Whether these phenotypes are more accurate in predicting cardiometabolic risk than BMI weight status is unknown. Methods: Dat ...

Article GUID: 34231966


Editorial: Advances in Dietary Fat Absorption

Author(s): Nauli AM; Santosa S; Dixon JB;

No abstract

Article GUID: 34168573


Putting ATM to BED: How Adipose Tissue Macrophages Are Affected by Bariatric Surgery, Exercise, and Dietary Fatty Acids

Author(s): Turner L; Santosa S;

With increasing adiposity in obesity, adipose tissue macrophages contribute to adipose tissue malfunction and increased circulating proinflammatory cytokines. The chronic low-grade inflammation that occurs in obesity ultimately gives rise to a state of meta ...

Article GUID: 33979430


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