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Mechanism of NH4(+) Recruitment and NH3 Transport in Rh Proteins

Author(s): Sefer Baday

In human cells, membrane proteins of the rhesus (Rh) family excrete ammonium and play a role in pH regulation. Based on high-resolution structures, Rh proteins are generally understood to act as NH3 channels. Given that cell membranes are permeable to gases like NH3, the role of such proteins remains a paradox. Using molecular and quantum mechanical calcu ...

Article GUID: 26190573


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