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Chloroplast biogenesis involves spatial coordination of nuclear and organellar gene expression in Chlamydomonas

Author(s): Sun Y; Bakhtiari S; Valente-Paterno M; Wu Y; Nishimura Y; Shen W; Law C; Dhaliwal J; Dai D; Bui KH; Zerges W; ...

The localization of translation can direct the polypeptide product to the proper intracellular compartment. Our results reveal translation by cytosolic ribosomes on a domain of the chloroplast enve ...

Article GUID: 38709497


Brain tumor detection based on a novel and high-quality prediction of the tumor pixel distributions

Author(s): Sun Y; Wang C;

The work presented in this paper is in the area of brain tumor detection. We propose a fast detection system with 3D MRI scans of Flair modality. It performs 2 functions, predicting the gray level distribution and location distribution of the pixels in the ...

Article GUID: 38493601


Mental health of Canadian youth: A systematic review and meta-analysis of studies examining changes in depression, anxiety, and suicide-related outcomes during the COVID-19 pandemic

Author(s): Geoffroy MC; Chadi N; Bouchard S; Fuoco J; Chartrand E; Loose T; Sciola A; Boruff JT; Iyer SN; Sun Y; Gouin JP; Côté SM; Thombs BD; ...

Objectives: This systematic review and meta-analysis aims to describe Canadian youth mental health during the COVID-19 pandemic, focusing on changes in anxiety and depressive symptoms and suicidali ...

Article GUID: 38478216


Promoting Cross-Regional Integration of Maritime Emission Management: A Euro-American Linkage of Carbon Markets

Author(s): Peng H; An C; Chen Z; Tian X; Sun Y;

Reducing greenhouse gas emissions from maritime transport is an urgent topic. Some regional emissions trading systems (ETSs), buoyed by the globalized market-based measures (MBMs) plan of the International maritime organization, have initially assessed the ...

Article GUID: 37556349


Real-world serological responses to extended-interval and heterologous COVID-19 mRNA vaccination in frail, older people (UNCoVER): an interim report from a prospective observational cohort study

Author(s): Vinh DC; Gouin JP; Cruz-Santiago D; Canac-Marquis M; Bernier S; Bobeuf F; Sengupta A; Brassard JP; Guerra A; Dziarmaga R; Perez A; Sun Y; Li ...

Background: The use of COVID-19 vaccines has been prioritised to protect the most vulnerable-notably, older people. Because of fluctuations in vaccine availability, strategies such as delayed secon ...

Article GUID: 35224524


External validation of a shortened screening tool using individual participant data meta-analysis: A case study of the Patient Health Questionnaire-Dep-4

Author(s): Harel D; Levis B; Sun Y; Fischer F; Ioannidis JPA; Cuijpers P; Patten SB; Ziegelstein RC; Markham S; Benedetti A; Thombs BD; ...

Shortened versions of self-reported questionnaires may be used to reduce respondent burden. When shortened screening tools are used, it is desirable to maintain equivalent diagnostic accuracy to fu ...

Article GUID: 34780986


Overestimation of Postpartum Depression Prevalence Based on a 5-item Version of the EPDS: Systematic Review and Individual Participant Data Meta-analysis

Author(s): Thombs BD; Levis B; Lyubenova A; Neupane D; Negeri Z; Wu Y; Sun Y; He C; Krishnan A; Vigod SN; Bhandari PM; Imran M; Rice DB; Azar M; Chiovi ...

Objective: The Maternal Mental Health in Canada, 2018/2019, survey reported that 18% of 7,085 mothers who recently gave birth reported "feelings consistent with postpartum depression" based on scor ...

Article GUID: 33104415


Depression prevalence based on the Edinburgh Postnatal Depression Scale compared to Structured Clinical Interview for DSM DIsorders classification: Systematic review and individual participant data meta-analysis

Author(s): Lyubenova A; Neupane D; Levis B; Wu Y; Sun Y; He C; Krishnan A; Bhandari PM; Negeri Z; Imran M; Rice DB; Azar M; Chiovitti MJ; Saadat N; Rie ...

Objectives: Estimates of depression prevalence in pregnancy and postpartum are based on the Edinburgh Postnatal Depression Scale (EPDS) more than on any other method. We aimed to determine if any E ...

Article GUID: 33089942


Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patients.

Author(s): Thombs BD, Kwakkenbos L, Carrier ME, Bourgeault A, Tao L, Harb S, Gagarine M, Rice D, Bustamante L, Ellis K, Duchek D, Wu Y, Bhandari PM, Ne ...

J Psychosom Res. 2020 May 14;135:110132 Authors: Thombs BD, Kwakkenbos L, Carrier ME, Bourgeault A, Tao L, Harb S, Gagarine M, Rice D, Bustamante L, Ellis K, Duchek D, Wu Y, Bhandari PM, Neupane D ...

Article GUID: 32521358


Patient Health Questionnaire-9 scores do not accurately estimate depression prevalence: individual participant data meta-analysis

Author(s): Levis B; Benedetti A; Ioannidis JPA; Sun Y; Negeri Z; He C; Wu Y; Krishnan A; Bhandari PM; Neupane D; Imran M; Rice DB; Riehm KE; Saadat N; ...

Objectives: Depression symptom questionnaires are not for diagnostic classification. Patient Health Questionnaire-9 (PHQ-9) scores =10 are nonetheless often used to estimate depression prevalence. ...

Article GUID: 32105798


Probability of major depression diagnostic classification based on the SCID, CIDI and MINI diagnostic interviews controlling for Hospital Anxiety and Depression Scale - Depression subscale scores: An individual participant data meta-analysis of 73 primary studies

Author(s): Wu Y; Levis B; Sun Y; Krishnan A; He C; Riehm KE; Rice DB; Azar M; Yan XW; Neupane D; Bhandari PM; Imran M; Chiovitti MJ; Saadat N; Boruff J ...

Objective: Two previous individual participant data meta-analyses (IPDMAs) found that different diagnostic interviews classify different proportions of people as having major depression overall or ...

Article GUID: 31911325


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