Author(s): Zhen C; Wang L; Feng Y; Whiteway M; Hang S; Yu J; Lu H; Jiang Y;

Candidiasis, which presents a substantial risk to human well-being, is frequently treated with azoles. However, drug-drug interactions caused by azoles inhibiting the human CYP3A4 enzyme, together with increasing resistance of Candida species to azoles, rep ...

Article GUID: 38995235

Author(s): Li W; Feng Y; Feng Z; Wang L; Whiteway M; Lu H; Jiang Y;

Fluconazole (FLC) is extensively employed for the prophylaxis and treatment of invasive fungal infections (IFIs). However, the fungistatic nature of FLC renders pathogenic fungi capable of developing tolerance towards it. Consequently, converting FLC into a ...

Article GUID: 38929106

Author(s): Hou D; Zhan D; Wang L; Hassan IG; Sezer N;

Many factors contribute to the inherent uncertainty of energy consumption modeling in buildings. It is essential to perform a calibration and sensitivity analysis in order to manage these uncertainties. Despite the availability of several calibration method ...

Article GUID: 37936825

Author(s): Wang H; Gao RT; Nguyen NT; Bai J; Ren S; Liu X; Zhang X; Wang L;

Photoelectrochemical (PEC) water splitting is an attractive strategy to convert solar energy to hydrogen. However, the lifetime of PEC devices is restricted by the photocorrosion of semiconductors and the instability of co-catalysts. Herein, we report a fea ...

Article GUID: 37901939

Author(s): Shu C; Gaur A; Wang L; Lacasse MA;

The heatwave event to which the Ontario-Quebec area was subjected in 2018 resulted in significant morbidity and mortality. In this study, an investigation was conducted on how this heatwave affected the respective urban heat islands (UHIs) in Montreal and O ...

Article GUID: 37263436

Author(s): Gao RT; Nguyen NT; Nakajima T; He J; Liu X; Zhang X; Wang L; Wu L;

Photoelectrochemical (PEC) water splitting that functions in pH-neutral electrolyte attracts increasing attention to energy demand sustainability. Here, we propose a strategy to in situ form a NiB layer by tuning the composition of the neutral electrolyte w ...

Article GUID: 36598972

Author(s): Katal A; Leroyer S; Zou J; Nikiema O; Albettar M; Belair S; Wang L;

More frequent and severe extreme weather events such as heatwaves are among the most serious challenges to society in coping with the changing climate. To evaluate the impacts of the heatwave on large-scale urban areas, a multi-scale weather forecasting sys ...

Article GUID: 36587678

Author(s): Xie S; Mohammady M; Wang H; Wang L; Vaidya J; Hong Y;

Property preserving encryption techniques have significantly advanced the utility of encrypted data in various data outsourcing settings (e.g., the cloud). However, while preserving certain properties (e.g., the prefixes or order of the data) in the encrypt ...

Article GUID: 36506788

Author(s): Zhao Z; Li J; Zhang X; Wang L; Wang J; Lin T;

Perfluoroalkyl and polyfluoroalkyl substances (PFASs) have been frequently detected in groundwater globally. With the phase-out of perfluorooctane sulfonate (PFOS) and perfluorooctanate (PFOA) due to their risk to the ecosystem and human population, various ...

Article GUID: 35593984

Author(s): Albettar M; Leon Wang L; Katal A;

Airborne transmission of aerosols contributes to a large portion of the SARS-CoV-2 spread indoors. This study develops a real-time interactive web-based platform for the public to compare various strategies to curb indoor airborne transmission of COVID-19 i ...

Article GUID: 35261876

Author(s): Sun X; Zhang X; Wang L; Li Y; Muir DCG; Zeng EY;

Deep convolutional neural network (DCNN) has proved to be a promising tool for identifying organic chemicals of environmental concern. However, the uncertainty associated with DCNN predictions remains to be quantified. The training process contains many ran ...

Article GUID: 34388923