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APOE-ε4 is not associated with pure-tone hearing thresholds, visual acuity or cognition, cross-sectionally or over 3 years of follow up in the Canadian Longitudinal Study on Aging

Author(s): Mick P; Kabir R; Karunatilake M; Kathleen Pichora-Fuller M; Young TL; Sosero Y; Gan-Or Z; Wittich W; Phillips NA; ...

Introduction: Hearing loss and diminished visual acuity are associated with poorer cognition, but the underlying mechanisms are not understood. The apolipoprotein (APOE) e4 allelic variant may driv ...

Article GUID: 38547662


Strategies used during the cognitive evaluation of older adults with dual sensory impairment: a scoping review

Author(s): Dumassais S; Pichora-Fuller MK; Guthrie D; Phillips NA; Savundranayagam M; Wittich W;

Background: Dual sensory impairment (DSI), the combination of visual and hearing impairments, is associated with increased risk for age-related cognitive decline and dementia. Administering cognitive tests to individuals with sensory impair ...

Article GUID: 38506649


At-home computerized executive-function training to improve cognition and mobility in normal-hearing adults and older hearing aid users: a multi-centre, single-blinded randomized controlled trial

Author(s): Downey R; Gagné N; Mohanathas N; Campos JL; Pichora-Fuller KM; Bherer L; Lussier M; Phillips NA; Wittich W; St-Onge N; Gagné JP; Li K; ...

Background: Hearing loss predicts cognitive decline and falls risk. It has been argued that degraded hearing makes listening effortful, causing competition for higher-level cognitive resources need ...

Article GUID: 37864139


Does social connection mediate the association between neuroticism and cognition? Cross-sectional analysis of the Canadian Longitudinal Study on Aging

Author(s): Bethell J; Andrew MK; Hothi S; Mick P; Morgan D; O' Connell ME; Phillips NA; Stewart S; Walker JD; Wittich W; McGilton KS; ...

Objectives: This study tested the association between neuroticism and six cognitive measures, and examined the potential mediating roles of social connection (social isolation and loneliness) among ...

Article GUID: 37667914


Associations Between Cardiovascular Risk Factors and Audiometric Hearing: Findings From the Canadian Longitudinal Study on Aging

Author(s): Mick PT; Kabir R; Pichora-Fuller MK; Jones C; Moxham L; Phillips N; Urry E; Wittich W;

Objectives: The objectives of the study were to determine, among a population-based sample of Canadian adults, if risk factors for cardiovascular disease (alone and in combination) were associated with hearing loss. Cross-sectional and longitudinal associat ...

Article GUID: 37122082


Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer's disease

Author(s): Giroud N; Pichora-Fuller MK; Mick P; Wittich W; Al-Yawer F; Rehan S; Orange JB; Phillips NA; ...

Using data from the COMPASS-ND study we investigated associations between hearing loss and hippocampal volume as well as cortical thickness in older adults with subjective cognitive decline (SCD), ...

Article GUID: 36911511


Sex-Specific Interactions Between Hearing and Memory in Older Adults With Mild Cognitive Impairment: Findings From the COMPASS-ND Study

Author(s): Al-Yawer F; Pichora-Fuller MK; Wittich W; Mick P; Giroud N; Rehan S; Phillips NA;

Objectives: Hearing loss (HL) in older adults is associated with a decline in performance on cognitive tasks and the risk of developing dementia. However, very few studies have investigated sex-related effects on these associations. A previous study of cogn ...

Article GUID: 36607746


A Newly Identified Impairment in Both Vision and Hearing Increases the Risk of Deterioration in Both Communication and Cognitive Performance

Author(s): Guthrie DM; Williams N; Campos J; Mick P; Orange JB; Pichora-Fuller MK; Savundranayagam MY; Wittich W; Phillips NA; ...

Vision and hearing impairments are highly prevalent in adults 65 years of age and older. There is a need to understand their association with multiple health-related outcomes. We analyzed data from ...

Article GUID: 35859361


The effects of simulated and actual visual impairment on the Montreal Cognitive Assessment

Author(s): Stark Z; Morrice E; Murphy C; Wittich W; Johnson AP;

Many cognitive assessments include a visual component; however, adults may experience a decline in visual acuity with age. Scores on cognitive assessments of adults with visual impairments are typically lower than adults with normal vision, however, it is u ...

Article GUID: 35341447


Assessing optimal colour and illumination to facilitate reading: an analysis of print size

Author(s): Morrice E; Murphy C; Soldano V; Addona C; Wittich W; Johnson AP;

Purpose: This study examined how optimal colour/illumination conditions and the efficacy of the iPad, LuxIQ and Smart Bulb varied as a function of print size in younger, older and visually impaired adults. Methods: Participants with visual impairments and ...

Article GUID: 34549808


Visual Performance and Cortical Atrophy in Vision-Related Brain Regions Differ Between Older Adults with (or at Risk for) Alzheimer&#39,s Disease

Author(s): Rehan S; Giroud N; Al-Yawer F; Wittich W; Phillips N;

<strong>Background:</strong> Visual impairment is associated with deficits in cognitive function and risk for cognitive decline and Alzheimer's disease (AD).

<strong>Objective:</strong> The purpose of this study was to ...

Article GUID: 34397410


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