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The standard reconsolidation protocol for auditory fear-conditioning does not account for fear to the test context

Authors: Jason W Payne


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Description

Research on memory reconsolidation has relied heavily on the use of Pavlovian auditory cued-fear conditioning. Here, an auditory cue (CS) is paired with a footshock (US) and the CS is later able to evoke a freezing response when presented alone. Some treatments, when administered to conditioned subjects immediately following a CS-alone (memory reactivation) trial, can attenuate the freezing they display on subsequent CS-alone (test) trials, in the absence of the treatment. This reduction in...

Links

PubMed: https://pubmed.ncbi.nlm.nih.gov/37347748/

DOI: 10.1371/journal.pone.0287193