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Sex-Specific Interactions Between Hearing and Memory in Older Adults With Mild Cognitive Impairment: Findings From the COMPASS-ND Study

Author(s): Al-Yawer F; Pichora-Fuller MK; Wittich W; Mick P; Giroud N; Rehan S; Phillips NA;

Objectives: Hearing loss (HL) in older adults is associated with a decline in performance on cognitive tasks and the risk of developing dementia. However, very few studies have investigated sex-related effects on these associations. A previous study of cognitively healthy older adults showed an association between HL and lower cognitive performance in fem ...

Article GUID: 36607746


Electroencephalographic characteristics of children and adolescents with chronic musculoskeletal pain

Author(s): Ocay DD; Teel EF; Luo OD; Savignac C; Mahdid Y; Blain-Moraes S; Ferland CE;

Introduction: The pathophysiology of pediatric musculoskeletal (MSK) pain is unclear, contributing to persistent challenges to its management. Objectives: This study hypothesizes that children and adolescents with chronic MSK pain (CPs) will show differences in electroencephalography (EEG) features at rest and during thermal pain modalities when compared ...

Article GUID: 36601627


Xylan glucuronic acid side chains fix suberin-like aliphatic compounds to wood cell walls

Author(s): Derba-Maceluch M; Mitra M; Hedenström M; Liu X; Gandla ML; Barbut FR; Abreu IN; Donev EN; Urbancsok J; Moritz T; Jönsson LJ; Tsang A; Powlowski J; Master ER; Mellerowicz EJ;

Wood is the most important repository of assimilated carbon in the biosphere, in the form of large polymers (cellulose, hemicelluloses including glucuronoxylan, and lignin) that interactively form a composite, together with soluble extractives including phenolic and aliphatic compounds. Molecular ...

Article GUID: 36600379


Dynamic semiconductor-electrolyte interface for sustainable solar water splitting over 600 hours under neutral conditions

Author(s): Gao RT; Nguyen NT; Nakajima T; He J; Liu X; Zhang X; Wang L; Wu L;

Photoelectrochemical (PEC) water splitting that functions in pH-neutral electrolyte attracts increasing attention to energy demand sustainability. Here, we propose a strategy to in situ form a NiB layer by tuning the composition of the neutral electrolyte with the additions of nickel and borate species, which improves the PEC performance of the BiVO4 phot ...

Article GUID: 36598972


Physiological levels of cardiolipin acutely affect mitochondrial respiration in vascular smooth muscle cells

Author(s): Galambo D; Bergdahl A;

Cardiolipin (CL) is a phospholipid molecule found in the inner mitochondrial membrane, where it normally associates with and activates the respiratory complexes. Following myocardial infarction, CL gets released from necrotic cells, consequently affecting neighboring tissues. We have previously demonstrated that physiological concentrations of up to 100 µ ...

Article GUID: 36594049


New metabolic signature for Chagas disease reveals sex steroid perturbation in humans and mice

Author(s): Golizeh M; Nam J; Chatelain E; Jackson Y; Ohlund LB; Rasoolizadeh A; Camargo FV; Mahrouche L; Furtos A; Sleno L; Ndao M;

The causative agent of Chagas disease (CD), Trypanosoma cruzi, claims thousands of lives each year. Current diagnostic tools are insufficient to ensure parasitological detection in chronically infected patients has been achieved. A host-derived metabolic signature able to distinguish CD patients ...

Article GUID: 36590505


Outdoor heat stress assessment using an integrated multi-scale numerical weather prediction system: A case study of a heatwave in Montreal

Author(s): Katal A; Leroyer S; Zou J; Nikiema O; Albettar M; Belair S; Wang L;

More frequent and severe extreme weather events such as heatwaves are among the most serious challenges to society in coping with the changing climate. To evaluate the impacts of the heatwave on large-scale urban areas, a multi-scale weather forecasting system is designed by integrating different resolutions of the Canadian urbanized version of the Global ...

Article GUID: 36587678


Network analysis uncovers the communication structure of SARS-CoV-2 Spike protein identifying sites for immunogen design

Author(s): Manrique PD; Chakraborty S; Henderson R; Edwards RJ; Mansbach R; Nguyen K; Stalls V; Saunders C; Mansouri K; Acharya P; Korber B; Gnanakaran S;

The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has triggered myriad efforts to understand the structure and dynamics of this complex pathogen. The Spike glycoprotein of SARS-CoV-2 is a significant target for immunogens as it is the means by which the virus enters human cells, while simult ...

Article GUID: 36590900


Comment on: Variation and outcomes of liver-reducing dietary regimens before bariatric surgery: a national retrospective cohort study

Author(s): Ben-Porat T; Sherf-Dagan S; Bacon SL;

No abstract

Article GUID: 36567233


Degradation pathways for organic matter of terrestrial origin are widespread and expressed in Arctic Ocean microbiomes

Author(s): Grevesse T; Guéguen C; Onana VE; Walsh DA;

Background: The Arctic Ocean receives massive freshwater input and a correspondingly large amount of humic-rich organic matter of terrestrial origin. Global warming, permafrost melt, and a changing hydrological cycle will contribute to an intensification of terrestrial organic matter release to the Arctic Ocean. Although considered recalcitrant to degrada ...

Article GUID: 36566218


Double-Bind of Recruitment of Older Adults Into Studies of Successful Aging via Assistive Information and Communication Technologies: Mapping Review

Author(s): Khalili-Mahani N; Sawchuk K;

Background: Two fields of research and development targeting the needs of the aging population of the world are flourishing, successful aging and assistive information and communication technologies (A-ICTs). The risks of ageist stereotypes emerging from how we communicate in both discourses are long known. This raises questions about whether using specif ...

Article GUID: 36563033


Improving Family Presence in Long-Term Care during the COVID-19 Pandemic

Author(s): Gallant NL; Hardy MS; Beogo I; Conklin J; Connelly D; Kaasalainen S; Keefe J; Robitaille A; Yous ML; Fanaki C; Cameron C;

Family caregivers play a vital role in supporting the physical and mental health of long-term care (LTC) residents. Due to LTC visitor restrictions during the COVID-19 pandemic, residents (as well as family caregivers) showed significant adverse health outcomes due to a lack of family presence. T ...

Article GUID: 36562582


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