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Reinforcement learning for automatic quadrilateral mesh generation: A soft actor-critic approach

Author(s): Pan J; Huang J; Cheng G; Zeng Y;

This paper proposes, implements, and evaluates a reinforcement learning (RL)-based computational framework for automatic mesh generation. Mesh generation plays a fundamental role in numerical simulations in the area of computer aided design and engineering (CAD/E). It is identified as one of the critical issues in the NASA CFD Vision 2030 Study. Existing ...

Article GUID: 36375347


An RNA granule for translation quality control in Saccharomyces cerevisiae

Author(s): Dhaliwal JS; Panozzo C; Benard L; Zerges W;

Cytoplasmic RNA granules compartmentalize phases of the translation cycle in eukaryotes. We previously reported the localization of oxidized RNA to cytoplasmic foci called oxidized RNA bodies (ORBs) in human cells. We show here that ORBs are RNA granules in Saccharomyces cerevisiae. Several lines of evidence support a role of ORBs in the compartmentalizat ...

Article GUID: 36373798


Green building standards and the United Nations' Sustainable Development Goals

Author(s): Goubran S; Walker T; Cucuzzella C; Schwartz T;

Sustainable practices in the building industry are strongly influenced by published green and sustainable building and real-estate standards (GSBRES). Therefore, it is crucial to assess how these standards contribute to achieving the United Nations' Sustainable Development Goals (SDGs). This paper evaluates the extent to which GSBRESs align with the 2 ...

Article GUID: 36372039


Insights on the COVID-19 pandemic: Youth engagement through photovoice

Author(s): Pickering CJ; Al-Baldawi Z; McVean L; Adan M; Amany RA; Al-Baldawi Z; Baker L; O' Sullivan T;

Youth engagement in disaster risk reduction is a growing area of research, practice and policy. The COVID-19 pandemic highlighted the need for improved opportunities for youth to participate and have their voices heard. Our Photovoice study explores experiences, perceptions, and insights of youth ...

Article GUID: 36373152


Optogenetic stimulation of infralimbic cortex projections to the paraventricular thalamus attenuates context-induced renewal

Author(s): Brown A; Chaudhri N;

Contexts associated with prior reinforcement can renew extinguished conditioned responding. The prelimbic (PL) and infralimbic (IL) cortices are thought to mediate the expression and suppression of conditioned responding, respectively. Evidence suggests that PL inputs to the paraventricular nucleus of the thalamus (PVT) drive the expression of cue-induced ...

Article GUID: 36373226


Calcium activity is a degraded estimate of spikes

Author(s): Hart EE; Gardner MPH; Panayi MC; Kahnt T; Schoenbaum G;

Recording action potentials extracellularly during behavior has led to fundamental discoveries regarding neural function-hippocampal neurons respond to locations in space,1 motor cortex neurons encode movement direction,2 and dopamine neurons signal reward prediction errors3-observations undergirding current theories of cognition,4 movement,5 and learning ...

Article GUID: 36368324


A Synthetic Biosensor for Detecting Putrescine in Beef Samples

Author(s): Selim AS; Perry JM; Nasr MA; Pimprikar JM; Shih SCC;

Biogenic amines (BAs) are toxicological risks present in many food products. Putrescine is the most common foodborne BA and is frequently used as a quality control marker. Currently, there is a lack of regulation concerning safe putrescine limits in food as well as outdated food handling practices leading to unnecessary putrescine intake. Conventional met ...

Article GUID: 36356104


Cancer Survivors' Evolving Perceptions of a New Supportive Virtual Program

Author(s): Robb A; Brown TL; Durand A; Loiselle CG;

This qualitative study begins to explore cancer survivors' evolving perceptions of "Focus on the Future," a 6-week supportive virtual program led by trained volunteers and health care professionals. Through purposive sampling, participants (n = 10) enrolled in the program were individually interviewed shortly before attending, mid-way through, and at ...

Article GUID: 36354724


An experimental and modeling study on the penetration of spilled oil into thawing frozen soil

Author(s): Qu Z; An C; Mei Z; Yue R; Zhao S; Feng Q; Cai M; Wen J;

Oil spills are significant environmental accidents that have significant impacts on environmental and ecological health. Spill pollution in the cold regions may pose a particular challenge. To achieve a fast response, the oil transport mode such as penetration should be well understood. In this study, the oil penetration behavior in thawing frozen soil at ...

Article GUID: 36349394


Patient and family engagement in patient care and research in Canadian intensive care units: a national survey

Author(s): Burns KEA; McDonald E; Debigaré S; Zamir N; Vasquez M; Piche-Ayotte M; Oczkowski S;

Purpose: While patient and family engagement may improve clinical care and research, current practices for engagement in Canadian intensive care units (ICUs) are unknown. Methods: We developed and administered a cross-sectional questionnaire to ICU leaders of current engagement practices, facilitators, and barriers to engagement, and whether engagement w ...

Article GUID: 36344874


Canadian Cardiovascular Harmonized National Guideline Endeavour (C-CHANGE) guideline for the prevention and management of cardiovascular disease in primary care: 2022 update

Author(s): Jain R; Stone JA; Agarwal G; Andrade JG; Bacon SL; Bajaj HS; Baker B; Cheng G; Dannenbaum D; Gelfer M; Habert J; Hickey J; Keshavjee K; Kitty D; Lindsay P; L' Abbé MR; Lau DCW; Macle L; McDonald M; Nerenberg K; Pearson GJ; Pham T; Poppe AY; Rabi DM; Sherifali D; Selby P; Smith E; Stern S; Th ...

No abstract

Article GUID: 36343954


Cerebral blood flow in schizophrenia: A systematic review and meta-analysis of MRI-based studies

Author(s): Percie du Sert O; Unrau J; Gauthier CJ; Chakravarty M; Malla A; Lepage M; Raucher-Chéné D;

Introduction: Schizophrenia-spectrum disorders (SSD) represent one of the leading causes of disability worldwide and are usually underpinned by neurodevelopmental brain abnormalities observed on a structural and functional level. Nuclear medicine imaging studies of cerebral blood ...

Article GUID: 36341843


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