Author(s): Mohammad K; Orfanos E; Titorenko VI;

After budding yeast cells cultured in a nutrient-rich liquid medium with 0.2% glucose (under caloric restriction conditions) or 2% glucose (under non-caloric restriction conditions), ferment glucose to ethanol and then consume ethanol, they enter the stationary phase. The process of their chronological aging begins. At that point, the yeast culture starts ...

Article GUID: 34853658

Author(s): LeCocq MR; Sun S; Chaudhri N;

Re-exposure to an unconditioned stimulus (US) can reinstate extinguished conditioned responding elicited by a conditioned stimulus (CS). We tested the hypothesis that the reinstatement of responding to an appetitive CS is driven by an excitatory association formed between the US and the context that the US was ingested in during US re-exposure. Male, Long ...

Article GUID: 34852244

Author(s): Garge RK; Cha HJ; Lee C; Gollihar JD; Kachroo AH; Wallingford JB; Marcotte EM;

Thiabendazole (TBZ) is an FDA-approved benzimidazole widely used for its antifungal and antihelminthic properties. We showed previously that TBZ is also a potent vascular disrupting agent and inhibits angiogenesis at the tissue level by dissociating vascular endothelial cells in newly formed blood vessels. Here, we uncover TBZ's molecular target and m ...

Article GUID: 34849907

Author(s): Omran RP; Ramírez-Zavala B; Aji Tebung W; Yao S; Feng J; Law C; Dumeaux V; Morschhäuser J; Whiteway M;

Zinc cluster transcription factors are essential fungal regulators of gene expression. In the pathogen Candida albicans, the gene orf19.1604 encodes a zinc cluster transcription factor regulating filament development. Hyperactivation of orf19.1604, which we have named RHA1 for Regulator of Hyphal ...

Article GUID: 34849863

Author(s): Wolfe J; Deroche M; Neumann S; Hanna L; Towler W; Wilson C; Bien AG; Miller S; Schafer EC; Gracco V;

<strong>Background:</strong> Considerable variability exists in the speech recognition abilities achieved by children with cochlear implants (CIs) due to varying demographic and performance variables including language abilities.

<strong>Purpose:</strong> This ar ...

Article GUID: 34847584

Author(s): Robert C; Patel R; Blostein N; Steele CC; Mallar Chakravarty M;

The striatum is a major subcortical connection hub that has been heavily implicated in a wide array of motor and cognitive functions. Here, we developed a normative multimodal, data-driven microstructural parcellation of the striatum using non-negative matrix factorization (NMF) based on multiple magnetic resonance imaging-based metrics (mean diffusivity, ...

Article GUID: 34848302

Author(s): Darwish A; Norouzi S; Kadem L;

Purpose: Identification of coherent structures in cardiovascular flows is crucial to describe the transport and mixing of blood. Coherent structures can highlight locations where minimal blood mixing takes place, thus, potential thrombus formation can be expected thither. Graph-based approaches have recently been introduced in order to describe fluid tran ...

Article GUID: 34845627

Author(s): Arsalan Rahimabadi

Considering the reaction schemes (20) and (21) in Fornari et al., 2020, the fragmentation terms Fi (Eq. (22) in Fornari et al., 2020) are not correct. Thus, the fragmentation terms Fi (Eq. (12) in Fornari et al., 2020) are also incorrect when the reaction schemes (10) and (11) in Fornari et al., 2020 are taken into account. Here, the correct equations wil ...

Article GUID: 34843739

Author(s): Véronneau MH; Serbin LA; Kennedy-Turner K; Stack DM; Ledingham JE; Schwartzman AE;

Governments around the world are pressed to invest in postsecondary education. However, little research exists to document whether large-scale educational reforms aimed at increasing rates of postsecondary attendance benefit youth's developmental outcomes. This study tested whether an educational reform occurring in Québec, Canada, in the 1960s increa ...

Article GUID: 34843080

Author(s): Zaker A; Chen Z; Lee K; Hammouda SB;

Recovery of oil spilled on surface waters by the use of sorbents remains one of the primary oil spill response options available. To improve on this response measure, we have successfully fabricated an activated char (AC) sorbent material by pyrolysis of sewage sludge (SS), a readily available waste product generated across the world from wastewater treat ...

Article GUID: 34842051

Author(s): Doniec R; Wójcik S; Valverde R; Piaseczna N; Siecinski S; Duraj K; Tkacz E;

The pandemic declared in many countries in 2020 due to COVID-19 led to the freezing of economies and the introduction of distance learning in both schools and universities. This unusual situation has affected the mental state of citizens, which has the potential to lead to the development of post-traumatic stress and depression. This study aimed to assess ...

Article GUID: 34828557

Author(s): Raab ME; Maurizio SL; Capobianco JA; Prasad PN;

Emission bands from thermally coupled states in lanthanide-doped nanoparticles have been studied for ratiometric nanothermometry in biological applications. Unfortunately certain factors such as water absorption distort the intensity, limiting the accuracy of ratiometric nanothermometry. However, the decay time of such states does not suffer from such dis ...

Article GUID: 34813703