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A Novel Freshwater to Marine Evolutionary Transition Revealed within Methylophilaceae Bacteria from the Arctic Ocean

Author(s): Ramachandran A; McLatchie S; Walsh DA;

Bacteria inhabiting polar oceans, particularly the Arctic Ocean, are less studied than those at lower latitudes. Discovering bacterial adaptations to Arctic Ocean conditions is essential for understanding responses to the accelerated environmental changes occurring in the North. The Methylophilaceae are emerging as a model for investigating the genomic ba ...

Article GUID: 34154421


Knowledge, Attitude, and Self-Reported Practice Towards Measures for Prevention of the Spread of COVID-19 Among Australians: A Nationwide Online Longitudinal Representative Survey

Author(s): Enticott J; Slifirski W; Lavoie KL; Bacon SL; Teede HJ; Boyle JA;

bjective: To assess and share learnings on the motivators and behavioural adherence across sex and age to evolving strategies in public policy to prevent the spread of SARS-CoV-2 at the end of a first COVID-19 wave and the beginning of a second COVID-19 wave in Australia. Design and Setting: A national longitudinal survey using a framework based on eviden ...

Article GUID: 34150696


Amyloid-β (1-42) peptide induces rapid NMDA receptor-dependent alterations at glutamatergic synapses in the entorhinal cortex

Author(s): Olajide OJ; Chapman CA;

The hippocampus and entorhinal cortex (EC) accumulate amyloid beta peptides (Aß) that promote neuropathology in Alzheimer's disease, but the early effects of Aß on excitatory synaptic transmission in the EC have not been well characterized. To assess the acute effects of Aß1-42 on glutamatergic synapses, acute brain slices from wildtype rats were expo ...

Article GUID: 34144329


Following spatial Aβ aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics

Author(s): Michno W; Stringer KM; Enzlein T; Passarelli MK; Escrig S; Vitanova K; Wood J; Blennow K; Zetterberg H; Meibom A; Hopf C; Edwards FA; Hanrieder J;

ß-Amyloid (Aß) plaque formation is the major pathological hallmark of Alzheimer's disease (AD) and constitutes a potentially critical, early inducer driving AD pathogenesis as it precedes other pathological events and cognitive symptoms by decades. It is therefore critical to understand how A ...

Article GUID: 34134980


Accomplishing breakthroughs in behavioural medicine research

Author(s): Davidson KW; Bacon SL; Bennett GG; Brondolo E; Czajkowski SM; Diefenbach MA; Epel ES; Matthews K; Revenson TA; Ruiz JM; Segerstrom SC;

No abstract

Article GUID: 34127817


Resampling the pool of genotypic possibilities: an adaptive function of sexual reproduction

Author(s): Hickey DA; Golding GB;

Background: Natural populations harbor significant levels of genetic variability. Because of this standing genetic variation, the number of possible genotypic combinations is many orders of magnitude greater than the population size. This means that any given population contains only a tiny fraction of all possible genotypic combinations. Results: We sho ...

Article GUID: 34118864


Emotion regulation from infancy to toddlerhood: Individual and group trajectories of full-term and very-low-birthweight preterm infants

Author(s): Atkinson NH; Jean ADL; Stack DM;

Adaptive emotion regulation begins with infants operating jointly with their parents to regulate their emotions, which fosters the development of independent regulation. Little is known about when or how this transition occurs, or the impact of factors such as parental availability or premature birth status. The current study examined the use of self-soot ...

Article GUID: 34120406


COVID-FACT: A Fully-Automated Capsule Network-Based Framework for Identification of COVID-19 Cases from Chest CT Scans

Author(s): Heidarian S; Afshar P; Enshaei N; Naderkhani F; Rafiee MJ; Babaki Fard F; Samimi K; Atashzar SF; Oikonomou A; Plataniotis KN; Mohammadi A;

The newly discovered Coronavirus Disease 2019 (COVID-19) has been globally spreading and causing hundreds of thousands of deaths around the world as of its first emergence in late 2019. The rapid outbreak of this disease has overwhelmed health care infrastructures and arises the need to allocate ...

Article GUID: 34113843


Blocking utilization of major plant biomass polysaccharides leads Aspergillus niger towards utilization of minor components

Author(s): Kun RS; Garrigues S; Di Falco M; Tsang A; de Vries RP;

Fungi produce a wide range of enzymes that allow them to grow on diverse plant biomass. Wheat bran is a low-cost substrate with high potential for biotechnological applications. It mainly contains cellulose and (arabino)xylan, as well as starch, proteins, lipids and lignin to a lesser extent. In this study, we dissected the regulatory network governing wh ...

Article GUID: 34114741


Clustering of Unhealthy Behaviors: Protocol for a Multiple Behavior Analysis of Data From the Canadian Longitudinal Study on Aging

Author(s): van Allen Z; Bacon SL; Bernard P; Brown H; Desroches S; Kastner M; Lavoie K; Marques M; McCleary N; Straus S; Taljaard M; Thavorn K; Tomasone JR; Presseau J;

<strong>Background:</strong> Health behaviors such as physical inactivity, unhealthy eating, smoking tobacco, and alcohol use are leading risk factors for noncommunicable chronic diseases and play a central role in limiting health and life satisfaction. To date, however, health behavi ...

Article GUID: 34114962


Intersections of Treatment, Surveillance, and Criminal Law Responses to HIV and COVID-19

Author(s): Hastings C; McClelland A; Guta A; Owino M; Manning E; Orsini M; Elliott R; Gagnon M; Molldrem S;

No abstract available

Article GUID: 34110919


Characterizing white matter alterations subject to clinical laterality in drug-naïve de novo Parkinson's disease

Author(s): Xiao Y; Peters TM; Khan AR;

Parkinson's disease (PD) is a progressive neurodegenerative disorder that is characterized by a range of motor and nonmotor symptoms, often with the motor dysfunction initiated unilaterally. Knowledge regarding disease-related alterations in white matter pathways can effectively help improve the understanding of the disease and propose targeted treatm ...

Article GUID: 34106502


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