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Exploiting protein language models for the precise classification of ion channels and ion transporters

Author(s): Ghazikhani H; Butler G;

This study introduces TooT-PLM-ionCT, a comprehensive framework that consolidates three distinct systems, each meticulously tailored for one of the following tasks: distinguishing ion channels (ICs) from membrane proteins (MPs), segregating ion transporters (ITs) from MPs, and differentiating ICs from ITs. Drawing upon the strengths of six Protein Languag ...

Article GUID: 38656743


All together now: Assessing variation in maternal and nonmaternal handling of wild Colobus vellerosus infants

Author(s): King AG; Rissling T; Cote S; Sicotte P;

Primatologists have a long-standing interest in the study of maternal care and nonmaternal handling (NH) of infants stemming from recognition that early social relationships can have enduring consequences. Though maternal care and NH often include expression of similar behaviors, they are regularly studied in isolation from each other with nonoverlapping ...

Article GUID: 38654439


Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies

Author(s): Husser MC; Pham NP; Law C; Araujo FRB; Martin VJJ; Piekny A;

Endogenous tags have become invaluable tools to visualize and study native proteins in live cells. However, generating human cell lines carrying endogenous tags is difficult due to the low efficiency of homology-directed repair. Recently, an engineered split mNeonGreen protein was used to generate a large-scale endogenous tag library in HEK293 cells. Usin ...

Article GUID: 38652106


Navigating the nexus: climate dynamics and microplastics pollution in coastal ecosystems

Author(s): Ahmed Dar A; Chen Z; Sardar MF; An C;

Microplastics (MPs) pollution is an emerging environmental health concern, impacting soil, plants, animals, and humans through their entry into the food chain via bioaccumulation. Human activities such as improper solid waste dumping are significant sources that ultimately transport MPs into the water bodies of the coastal areas. Moreover, there is a comp ...

Article GUID: 38642636


Rare-earth acetates as alternative precursors for rare-earth cluster-based metal-organic frameworks

Author(s): Richezzi M; Donnarumma PR; Copeman C; Howarth AJ;

RE-UiO-66 analogues are synthesized using RE acetates as precursors for the first time. These MOFs are fully characterized and the influence of the precursor on the materials obtained is studied. Additionally, the influence of water on the yield of the syntheses and the quality of the materials is explored.

Article GUID: 38646995


Papers from the 17th Joint Workshop on Augmented Environments for Computer Assisted Interventions at MICCAI 2023: Guest Editors' Foreword

Author(s): Linte CA; Yaniv Z; Chen E; Dou Q; Drouin S; Kalia M; Kersten-Oertel M; McLeod J; Sarikaya D;

No abstract available

Article GUID: 38638501


Assessment of urban greenhouse gas emissions towards reduction planning and low-carbon city: a case study of Montreal, Canada

Author(s): Shadnoush Pashaei

Greenhouse gases (GHGs) can be produced from a broad range of anthropogenic activities at different spatial and temporal scales. In particular, emissions from urban area are an import source of GHGs. City is a complicated system consisting of various component and processes. Efforts have been made to reduce urban GHG emissions. However, there is a lack of ...

Article GUID: 38638449


Breamy: An augmented reality mHealth prototype for surgical decision-making in breast cancer

Author(s): Najafi N; Addie M; Meterissian S; Kersten-Oertel M;

Breast cancer is one of the most prevalent forms of cancer, affecting approximately one in eight women during their lifetime. Deciding on breast cancer treatment, which includes the choice between surgical options, frequently demands prompt decision-making within an 8-week timeframe. However, many women lack the necessary knowledge and preparation for mak ...

Article GUID: 38638506


Co-Development of Three Dietary Indices to Facilitate Dietary Intake Assessment of Pediatric Crohn's Disease Patients

Author(s): Harvey A.; Mannette J.; Sigall-Boneh R.; Macintyre B.; Parrott M.; Cahill L.; Connors J.; Otley A.; Haskett J.; van Limbergen J.; Grant S.;

Literature on dietary behaviours of the pediatric Crohn's Disease (CD) population and the relationship between dietary intake and CD activity is limited. Three dietary indices were developed and tested to conduct dietary pattern analysis in pediatric patients with CD consuming a free diet fol ...

Article GUID: 38634640


A polyphenol-rich cranberry supplement improves muscle oxidative capacity in healthy adults

Author(s): Parenteau F; Denis A; Roberts M; Comtois AS; Bergdahl A;

Cranberries are rich in polyphenols, have a high antioxidant capacity, and may protect against exercise-induced free radical production. Mitochondria are known producers of free radical in skeletal muscle, and preventing overproduction of radicals may be a viable approach to improve muscle health. This study aimed to investigate the effect of a polyphenol ...

Article GUID: 38626462


ALBA: a model-driven framework for the automatic generation of android location-based apps

Author(s): Gharaat M; Sharbaf M; Zamani B; Hamou-Lhadj A;

In recent years, the number of smartphone users has increased dramatically. These users download millions of apps and use them for various services. Due to the significant demand for mobile apps, developers often seek faster development methods and more effective tools and techniques to generate these apps. Many of these apps are location-based apps in wh ...

Article GUID: 38624616


Numerical Simulation of the Effect of Particle and Substrate Preheating on Porosity Level and Residual Stress of As-sprayed Ti6Al4V Components

Author(s): Khamsepour P; Moreau C; Dolatabadi A;

Nowadays, in the aerospace industry, additive manufacturing and repairing damaged metallic components like Ti6Al4V samples have grabbed attention. Among repairing techniques, solid-state additive manufacturing processes like cold spray are promising because of their unique benefits such as high deposition rate with almost no oxidation in the deposited mat ...

Article GUID: 38624932


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