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Voice characteristics from isolated rapid eye movement sleep behavior disorder to early Parkinson's disease

Author(s): Laetitia Jeancolas

CONCLUSION: This study provides new insight in the characterization of sex-dependent early PD speech impairments, and demonstrates the valuable benefit of including automated voice analysis in future diagnostic procedures of prodromal PD.

Article GUID: 35063866


Natural history and determinants of dysglycemia in Canadian children with parental obesity from ages 8-10 to 15-17 years: The QUALITY cohort

Author(s): Soren Harnois-Leblanc

In children, the mechanisms implicated in deterioration of glucose homeostasis versus reversion to normal glucose tolerance (NGT) remain uncertain. We aimed to describe the natural history of dysglycemia from childhood to late adolescence and to identify it ...

Article GUID: 35023257


Promoting healthy lifestyle behaviours in youth: Findings from a novel intervention for children at risk of cardiovascular disease

Author(s): Ybarra M; Danieles PK; Barnett TA; Mathieu MÈ; Van Hulst A; Drouin O; Kakinami L; Bigras JL; Henderson M; ...

Objectives: Obesity is the most prevalent risk factor for cardiovascular disease (CVD) in children. We developed a 2-year lifestyle intervention for youth at risk of CVD. We assessed changes in bod ...

Article GUID: 34992701


Sex differences in regional adipose tissue depots pose different threats for the development of Type 2 diabetes in males and females

Author(s): Kerri Z Delaney

Type 2 diabetes mellitus (T2DM) affects males and females disproportionately. In midlife, more males have T2DM than females. The sex difference in T2DM prevalence is, in part, explained by differences in regional adipose tissue characteristics. With obesity ...

Article GUID: 34985183


Play the Pain: A Digital Strategy for Play-Oriented Research and Action

Author(s): Najmeh Khalili-Mahani

The value of understanding patients' illness experience and social contexts for advancing medicine and clinical care is widely acknowledged. However, methodologies for rigorous and inclusive data gathering and integrative analysis of biomedical, cultura ...

Article GUID: 34975566


Concurrent Validity of the Adult Eating Behavior Questionnaire in a Canadian Sample

Author(s): Cohen TR; Kakinami L; Plourde H; Hunot-Alexander C; Beeken RJ;

The current study aimed to test the factor structure of the Adult Eating Behavior Questionnaire (AEBQ), its construct validity against the Three-Factor Eating Questionnaire (TFEQ-R18) and its associations with body mass index (BMI) in Canadian adults (n = 5 ...

Article GUID: 34925181


Sleep disorders in patients with a neurocognitive disorder

Author(s): C Moderie

CONCLUSION: Multiple and sustained nonpharmacological approaches are recommended for the treatment of sleep disturbances in patients with neurocognitive disorder. Pharmacological indications remain limited, and further randomized clinical trials integrating ...

Article GUID: 34916075


A comparison of the effect of physical activity and cognitive training on dual-task performance in older adults

Author(s): Vrinceanu T; Blanchette CA; Intzandt B; Lussier M; Pothier K; Vu TTM; Nigam A; Bosquet L; Karelis AD; Li KZH; Berryman N; Bherer L; ...

Objectives: Studies suggest that cognitive training and physical activity can improve age-related deficits in dual-task performances. However, both of these interventions have never been compared i ...

Article GUID: 34865009


The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans

Author(s): Omran RP; Ramírez-Zavala B; Aji Tebung W; Yao S; Feng J; Law C; Dumeaux V; Morschhäuser J; Whiteway M; ...

Zinc cluster transcription factors are essential fungal regulators of gene expression. In the pathogen Candida albicans, the gene orf19.1604 encodes a zinc cluster transcription factor regulating f ...

Article GUID: 34849863


Comment on the article "Spatially-extended nucleation-aggregation-fragmentation models for the dynamics of prion-like neurodegenerative protein-spreading in the brain and its connectome 486 (2020) 110102"

Author(s): Arsalan Rahimabadi

Considering the reaction schemes (20) and (21) in Fornari et al., 2020, the fragmentation terms Fi (Eq. (22) in Fornari et al., 2020) are not correct. Thus, the fragmentation terms Fi (Eq. (12) in Fornari et al., 2020) are also incorrect when the reaction s ...

Article GUID: 34843739


Assessment of the Relationship Between Executive Function and Cardiorespiratory Fitness in Healthy Older Adults

Author(s): Predovan D; Berryman N; Lussier M; Comte F; Vu TTM; Villalpando JM; Bherer L;

Associations between cardiorespiratory fitness and brain health in healthy older adults have been reported using a variety of cardiorespiratory fitness estimates (CRFe). Using commonly used methods to determine CRF, we assessed the relationship between CRFe ...

Article GUID: 34803824


Intuitive eating and its association with psychosocial health in adults: A cross-sectional study in a representative Canadian sample

Author(s): Gödde JU; Yuan TY; Kakinami L; Cohen TR;

Intuitive eating has been proposed as a weight-inclusive, effective, and sustainable approach to eating that benefits psychosocial health compared to traditional restrictive dieting. This cross-sectional study examined the associations of intuitive eating w ...

Article GUID: 34740711


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