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X-Vectors: New Quantitative Biomarkers for Early Parkinson's Disease Detection From Speech

Author(s): Jeancolas L; Petrovska-Delacrétaz D; Mangone G; Benkelfat BE; Corvol JC; Vidailhet M; Lehéricy S; Benali H; ...

Many articles have used voice analysis to detect Parkinson's disease (PD), but few have focused on the early stages of the disease and the gender effect. In this article, we have adapted the la ...

Article GUID: 33679361


Determinants of attrition in a pediatric healthy lifestyle intervention: The CIRCUIT program experience

Author(s): Danieles PK; Ybarra M; Van Hulst A; Barnett TA; Mathieu MÈ; Kakinami L; Drouin O; Bigras JL; Henderson M; ...

Introduction: Attrition in pediatric weight management programs is notoriously high. Greater understanding of its determinants is needed to inform retention strategies. We identified determinants o ...

Article GUID: 33608233


Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring.

Author(s): Lismer A, Dumeaux V, Lafleur C, Lambrot R, Brind'Amour J, Lorincz MC, Kimmins S

A father's lifestyle impacts offspring health; yet, the underlying molecular mechanisms remain elusive. We hypothesized that a diet that changes methyl donor availability will alter the sperm and embryo epigenomes to impact embryonic gene expression and ...

Article GUID: 33596408


Association between rs174537 FADS1 polymorphism and immune cell profiles in abdominal and femoral subcutaneous adipose tissue: an exploratory study in adults with obesity

Author(s): Wang C; Murphy J; Delaney KZ; Khor N; Morais JA; Tsoukas MA; Lowry DE; Mutch DM; Santosa S; ...

Fatty acid desaturase 1 (FADS1) polymorphisms alter fatty acid content in subcutaneous adipose tissue (SAT); however, existing evidence is limited and conflicting regarding the association between ...

Article GUID: 33595419


Resource-rational approach to meta-control problems across the lifespan

Author(s): Ruel A; Devine S; Eppinger B;

Over the last decade, research on cognitive control and decision-making has revealed that individuals weigh the costs and benefits of engaging in or refraining from control and that whether and how they engage in these cost-benefit analyses may change acros ...

Article GUID: 33590729


Heart rate variability moderates the between- and within-person associations between daily stress and negative affect

Author(s): da Estrela C; MacNeil S; Gouin JP;

Stress exposure increases risk for depressive symptoms. However, there are substantial individual differences in affective responses to stress. High-frequency heart rate variability (HF-HRV), a marker of vagally-mediated parasympathetic activity, has been c ...

Article GUID: 33556470


CCCDTD5: Clinical role of neuroimaging and liquid biomarkers in patients with cognitive impairment

Author(s): Brisson M; Brodeur C; Létourneau-Guillon L; Masellis M; Stoessl J; Tamm A; Zukotynski K; Ismail Z; Gauthier S; Rosa-Neto P; Soucy JP; ...

Since 1989, four Canadian Consensus Conferences on the Diagnosis and Treatment of Dementia (CCCDTDs) have provided evidence-based dementia diagnostic and treatment guidelines for Canadian clinician ...

Article GUID: 33532543


Acceptability of a structured diet and exercise weight loss intervention in breast cancer survivors living with an overweight condition or obesity: A qualitative analysis.

Author(s): Beckenstein H, Slim M, Kim H, Plourde H, Kilgour R, Cohen TR

BACKGROUND: Weight loss increases survivorship following breast cancer diagnosis. However, most breast cancer survivors (BCS) do not meet diet and exercise recommendations. AIM: The purpose of this study was to explore the barriers and facilitators of BCS w ...

Article GUID: 33491338


Fast oscillations >40 Hz localize the epileptogenic zone: An electrical source imaging study using high-density electroencephalography.

Author(s): Avigdor T, Abdallah C, von Ellenrieder N, Hedrich T, Rubino A, Lo Russo G, Bernhardt B, Nobili L, Grova C, Frauscher B ...

OBJECTIVE: Fast Oscillations (FO) >40 Hz are a promising biomarker of the epileptogenic zone (EZ). Evidence using scalp electroencephalography (EEG) remains scarce. We assessed if electrical source ...

Article GUID: 33450578


Large-scale mGluR5 network abnormalities linked to epilepsy duration in focal cortical dysplasia.

Author(s): DuBois JM, Mathotaarachchi S, Rousset OG, Sziklas V, Sepulcre J, Guiot MC, Hall JA, Massarweh G, Soucy JP, Rosa-Neto P, Kobayashi E ...

To determine the extent of metabotropic glutamate receptor type 5 (mGluR5) network abnormalities associated with focal cortical dysplasia (FCD), we performed graph theoretical analysis of [11C]ABP6 ...

Article GUID: 33401137


PASS: A Multimodal Database of Physical Activity and Stress for Mobile Passive Body/ Brain-Computer Interface Research

Author(s): Parent M; Albuquerque I; Tiwari A; Cassani R; Gagnon JF; Lafond D; Tremblay S; Falk TH;

With the burgeoning of wearable devices and passive body/brain-computer interfaces (B/BCIs), automated stress monitoring in everyday settings has gained significant attention recently, with applications ranging from serious games to clinical monitoring. Wit ...

Article GUID: 33363449


WAUC: A Multi-Modal Database for Mental Workload Assessment Under Physical Activity

Author(s): Albuquerque I; Tiwari A; Parent M; Cassani R; Gagnon JF; Lafond D; Tremblay S; Falk TH;

Assessment of mental workload is crucial for applications that require sustained attention and where conditions such as mental fatigue and drowsiness must be avoided. Previous work that attempted to devise objective methods to model mental workload were mai ...

Article GUID: 33335465


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