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Palatability attributed to alcohol and alcohol-paired flavors

Author(s): Valyear MD; Eustachon NM; Britt JP;

The orosensory features of alcoholic drinks are potent relapse triggers because they acquire incentive properties during consumption, including enhanced palatability. Whether mice similarly perceive alcoholic drinks to be more palatable after repeated consu ...

Article GUID: 38430645


Augmenting glutamatergic, but not dopaminergic, activity in the nucleus accumbens shell disrupts responding to a discrete alcohol cue in an alcohol context

Author(s): Valyear MD; Brown A; Deyab G; Villaruel FR; Lahlou S; Caporicci-Dinucci N; Chaudhri N;

Discrete alcohol cues and contexts are relapse triggers for people with alcohol use disorder exerting particularly powerful control over behaviour when they co-occur. Here, we investigated the neural substrates subserving the capacity for alcohol-associated ...

Article GUID: 38185906


Learning from opioid withdrawal: Effects on striatal dopamine (Commentary on Ahn et al., 2023)

Author(s): Leyton M; Nikolic M;

No abstract available

Article GUID: 38129315


Does phasic dopamine release cause policy updates?

Author(s): Carter F; Cossette MP; Trujillo-Pisanty I; Pallikaras V; Breton YA; Conover K; Caplan J; Solis P; Voisard J; Yaksich A; Shizgal P; ...

Phasic dopamine activity is believed to both encode reward-prediction errors (RPEs) and to cause the adaptations that these errors engender. If so, a rat working for optogenetic stimulation of dopa ...

Article GUID: 38039083


What is Learned Determines How Pavlovian Conditioned Fear is Consolidated in the Brain

Author(s): Leake J; Leidl DM; Lay BPP; Fam JP; Giles MC; Qureshi OA; Westbrook RF; Holmes NM;

Activity in the basolateral amygdala complex (BLA) is needed to encode fears acquired through contact with both innate sources of danger (i.e., things that are painful) and learned sources of danger (e.g., being threatened with a gun). However, within the B ...

Article GUID: 37963767


NMDA Receptors in the Basolateral Amygdala Complex Are Engaged for Pavlovian Fear Conditioning When an Animal's Predictions about Danger Are in Error

Author(s): Tuval Keidar

It is widely accepted that Pavlovian fear conditioning requires activation of NMDA receptors (NMDARs) in the basolateral amygdala complex (BLA). However, it was recently shown that activation of NMDAR in the BLA is only required for fear conditioning when d ...

Article GUID: 37607821


Sub-hourly measurement datasets from 6 real buildings: Energy use and indoor climate

Author(s): Sartori I; Walnum HT; Skeie KS; Georges L; Knudsen MD; Bacher P; Candanedo J; Sigounis AM; Prakash AK; Pritoni M; Granderson J; Yang S; Wan ...

The data presented here were collected independently for 6 real buildings by researchers of different institutions and gathered in the context of the IEA EBC Annex 81 Data-driven Smart Buildings, a ...

Article GUID: 37153123


Danger Changes the Way the Brain Consolidates Neutral Information; and Does So by Interacting with Processes Involved in the Encoding of That Information

Author(s): Omar A Qureshi

This study examined the effect of danger on consolidation of neutral information in two regions of the rat (male and female) medial temporal lobe: the perirhinal cortex (PRh) and basolateral amygdala complex (BLA). The neutral information was the associatio ...

Article GUID: 36927572


A new circuit underlying the renewal of appetitive Pavlovian responses: Commentary on Brown and Chaudhri (2022)

Author(s): Valyear MD; Britt JP;

No abstract available

Article GUID: 36700576


Optogenetic stimulation of infralimbic cortex projections to the paraventricular thalamus attenuates context-induced renewal

Author(s): Brown A; Chaudhri N;

Contexts associated with prior reinforcement can renew extinguished conditioned responding. The prelimbic (PL) and infralimbic (IL) cortices are thought to mediate the expression and suppression of conditioned responding, respectively. Evidence suggests tha ...

Article GUID: 36373226


Learning processes in relapse to alcohol use: lessons from animal models

Author(s): Valyear MD; LeCocq MR; Brown A; Villaruel FR; Segal D; Chaudhri N;

Rationale: Alcohol use is reliably preceded by discrete and contextual stimuli which, through diverse learning processes, acquire the capacity to promote alcohol use and relapse to alcohol use. Objective: We review contemporary extinction, renewal, reinsta ...

Article GUID: 36264342


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