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Future-making through eventing human-machine listening

Author(s): Mona Hedayati

Reverb-Resonate: Sounding the Affective Frequencies of Migration operates at the intersection of art, science, and technology to articulate an emotional landscape of migration and exile. Rooted in the methodology of research-creation (RC) and grounded in th ...

Article GUID: 38938763


Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies

Author(s): Husser MC; Pham NP; Law C; Araujo FRB; Martin VJJ; Piekny A;

Endogenous tags have become invaluable tools to visualize and study native proteins in live cells. However, generating human cell lines carrying endogenous tags is difficult due to the low efficiency of homology-directed repair. Recently, an engineered spli ...

Article GUID: 38652106


Global assessment of effective population sizes: Consistent taxonomic differences in meeting the 50/500 rule

Author(s): Clarke SH; Lawrence ER; Matte JM; Gallagher BK; Salisbury SJ; Michaelides SN; Koumrouyan R; Ruzzante DE; Grant JWA; Fraser DJ; ...

Effective population size (Ne) is a particularly useful metric for conservation as it affects genetic drift, inbreeding and adaptive potential within populations. Current guidelines recommend a min ...

Article GUID: 38613250


Exploring the effects of anthropogenic disturbance on predator inspection activity in Trinidadian guppies

Author(s): Brusseau AJP; Feyten LEA; Crane AL; Brown GE;

No abstract available

Article GUID: 38476138


Evaluation of human vulnerability and toxic effects of chronic and acute occupational exposure to ammonia: A case study in an ice factory

Author(s): Soltanzadeh A; Mahdinia M; Nikbakht N; Hosseinzadeh K; Sadeghi-Yarandi M;

Background: The hazardous material release has frequently occurred worldwide. As a respiratory stimulant and a toxic substance, ammonia has numerous adverse effects on human health. Objective: The purpose of this study was to evaluate the human vulnerabili ...

Article GUID: 38143407


Primates and disability: Behavioral flexibility and implications for resilience to environmental change

Author(s): Stewart BM; Joyce MM; Creeggan J; Eccles S; Gerwing MG; Turner SE;

Congenital malformations, conditions, injuries, and illness can lead to long-term physical impairment and disability in nonhuman primates. How individual primates change their behaviors flexibly to compensate for their disabilities can inform our understand ...

Article GUID: 38050800


Species-specific protein-protein interactions govern the humanization of the 20S proteasome in yeast

Author(s): Sultana S; Abdullah M; Li J; Hochstrasser M; Kachroo AH;

Yeast and humans share thousands of genes despite a billion years of evolutionary divergence. While many human genes can functionally replace their yeast counterparts, nearly half of the tested shared genes cannot. For example, most yeast proteasome subunit ...

Article GUID: 37364278


Rapid, scalable, combinatorial genome engineering by marker-less enrichment and recombination of genetically engineered loci in yeast

Author(s): Abdullah M; Greco BM; Laurent JM; Garge RK; Boutz DR; Vandeloo M; Marcotte EM; Kachroo AH; ...

A major challenge to rationally building multi-gene processes in yeast arises due to the combinatorics of combining all of the individual edits into the same strain. Here, we present a precise and ...

Article GUID: 37323580


Human Activity Recognition with an HMM-Based Generative Model

Author(s): Manouchehri N; Bouguila N;

Human activity recognition (HAR) has become an interesting topic in healthcare. This application is important in various domains, such as health monitoring, supporting elders, and disease diagnosis. Considering the increasing improvements in smart devices, ...

Article GUID: 36772428


Sigma oscillations protect or reinstate motor memory depending on their temporal coordination with slow waves

Author(s): Nicolas J; King BR; Levesque D; Lazzouni L; Coffey EBJ; Swinnen S; Doyon J; Carrier J; Albouy G; ...

Targeted memory reactivation (TMR) during post-learning sleep is known to enhance motor memory consolidation but the underlying neurophysiological processes remain unclear. Here, we confirm the ben ...

Article GUID: 35726850


Humanized yeast to model human biology, disease and evolution

Author(s): Kachroo AH; Vandeloo M; Greco BM; Abdullah M;

For decades, budding yeast, a single-cellular eukaryote, has provided remarkable insights into human biology. Yeast and humans share several thousand genes despite morphological and cellular differences and over a billion years of separate evolution. These ...

Article GUID: 35661208


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