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Prioritizing treatment targets for youths with disruptive behaviours and callous-unemotional traits: a modified Delphi study

Author(s): Diep J; Chen E; Lui JHL;

Background: Youths with disruptive behaviours (DB) and callous-unemotional (CU) traits experience significant impairments and impose substantial costs on families and society. Treatment outcome studies of current DB treatments highlight the need for tailored treatments. Identifying priority treatment targets that integrate empirical evidence with stakehol ...

Article GUID: 42351288


Ureolytic bacteria for MICP application to iron-rich slag materials for waste stabilization and carbon sequestration

Author(s): Wilcox SM; Mulligan CN; Neculita CM;

Microbial induced carbonate precipitation (MICP) is a novel soil and cement strengthening technique for civil and geotechnical engineering fields. Recently emerging is the use of MICP as a biological remediation strategy to immobilize contaminants, strengthen metalliferous waste, and sequester carbon dioxide from mining activities. MICP has a broad spectr ...

Article GUID: 42325307


Sex differences in the association of adverse childhood experiences with brain and cognition along a continuum of risk for Alzheimer s disease

Author(s): Perovic M; Phillips NA; Einstein G;

Introduction: Women make up two-thirds of people with Alzheimer's disease (AD). Research has focused on biological explanations for this sex difference, while contributions of psychosocial risk factors are less well understood. Methods: We examined sex differences in the effects of adverse childhood experiences (ACEs) on late-life cognition in groups ...

Article GUID: 42325010


Whole-Night Gentle Rocking Improves Sleep in Poor Sleepers With Insomnia Complaints

Author(s): Perrault AA; Cross NE; Dang Vu TT; Schwartz S; Bayer L;

Specific brain oscillations can be manipulated during sleep to improve sleep quality and memory performance. We previously demonstrated that continuous rocking stimulation (0.25 Hz, lateral movement) applied to good sleepers during sleep enhanced stable deep sleep, boosted NREM oscillations (spindles and slow waves) and memory consolidation. Here, we inve ...

Article GUID: 42268039


No evidence of sex-specific responses to chemosensory risk assessment cues in Harts rivulus

Author(s): Brusseau AJP; Synnott FD; Nagl A; Morris J; Mathis A; Ramnarine IW; Crane AL; Brown GE;

Males and females, especially in species with more pronounced sexual dimorphisms, may face very different trade-offs between detecting and avoiding predation threats and the need to court potential mates. Within aquatic ecosystems, the use of reliable publicly available chemosensory risk assessment cues allows prey to assess local threats and optimize the ...

Article GUID: 42264418


Subthalamic segmentations in relation to deep brain stimulation volumes in Parkinson s disease

Author(s): Calvano A; Xiao Y; Steidel K; Loehrer PA; Ruppert-Junck MC; Nimsky C; Timmermann L; Bopp MHA; Pedrosa DJ;

Purpose: Accurate segmentation of the subthalamic nucleus (STN) is paramount for optimising outcomes under deep brain stimulation (DBS) in Parkinson's disease (PD). Clinically available tools like Brainlab Elements (BL-E) enable automated segmentations for surgical planning, yet their spatial ...

Article GUID: 42225900


Keeping an Eye on Looking Measures: Towards More Robust Developmental Methods

Author(s): Sander-Montant A; Fibla L; Killam H; Byers-Heinlein K;

A persistent challenge in experimental developmental psychology is determining which of many possible outcome measures best captures underlying behaviors and processes. In the looking-while-listening paradigm for studying early word comprehension, researchers have developed more than 12 distinct outcome measures, but have limited empirical basis for choos ...

Article GUID: 42206598


Investigating substrate specificity in arogenate versus prephenate dehydratases

Author(s): Clayton EJ; Smith-Uffen M; Tribble TW; Duennwald ML; Kohalmi SE;

Background: Phenylalanine is an essential aromatic amino acid that can only be synthesized de novo by microorganisms and plants. In microorganisms, phenylalanine is synthesized through the prephenate pathway, requiring the activity of a prephenate dehydratase (PDT). In plants, phenylalanine is synthesized instead mostly through the arogenate pathway, requ ...

Article GUID: 42204708


Bilingual Families Align Their Languages During Naturalistic Interactions: Evidence from Two Bilingual Communities

Author(s): Fibla L; Kosie JE; Tsui RK; Potter CE; Lew-Williams C; Byers-Heinlein K;

Bilingual children learn their languages through rich interactions with caregivers within dynamic family contexts. However, little is known about how families align their two languages to support bilingual acquisition and how this varies across bilingual communities. This study examines language choice alignment across two communities: French-English fami ...

Article GUID: 42193667


Does Intranasal Oxytocin Reduce Symptoms of Mental Disorders? A Meta-Analysis of Clinical Trials

Author(s): Bonnieux J; Gumuchian ST; Harboun A; Trespalacios F; Bélisle KA; Haddad A; Quintus-Bosz O; McLellan A; Chester-Trudel L; Garred D; Resendes T; Hazel L; Wong SF; Ellenbogen MA;

Intranasal administration of oxytocin has been shown to enhance social cognition and reduce stress reactivity in healthy individuals, suggesting therapeutic potential for mental disorders. However, clinical trials have produced mixed results. Following a systematic search, data were extracted fro ...

Article GUID: 42134427


Enhanced Lower Limb Strength and Dynamic Balance Among Older Canadian Women Following 12-Weeks of Online Ballet-Modern Dance Classes Combined with Blood Flow Restriction

Author(s): Chen EH; Saminathar AJ; Roberts M; Bergdahl A;

Introduction: Falls are a leading cause of hospitalization among older women. While dance classes have gained popularity to reduce the risk of falls, in-person classes may be inaccessible. Online classes provide feasible solutions, but are limited by the lower intensity required by the virtual environment. Blood flow restriction (BFR) provides a safe way ...

Article GUID: 42132210


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