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Corticostriatal suppression of appetitive Pavlovian conditioned responding

Author(s): Villaruel FR; Martins M; Chaudhri N;

The capacity to suppress learned responses is essential for animals to adapt in dynamic environments. Extinction is a process by which animals learn to suppress conditioned responding when an expected outcome is omitted. The infralimbic cortex (IL) to nucle ...

Article GUID: 34880119


The trade-off between pulse duration and power in optical excitation of midbrain dopamine neurons approximates Bloch's law

Author(s): Pallikaras V; Carter F; Velazquez-Martinez DN; Arvanitogiannis A; Shizgal P;

Optogenetic experiments reveal functional roles of specific neurons. However, functional inferences have been limited by widespread adoption of a restricted set of stimulation parameters. Broader exploration of the parameter space can deepen insight into th ...

Article GUID: 34864162


Seeing is believing: tools to study the role of Rho GTPases during cytokinesis

Author(s): Koh SP; Pham NP; Piekny A;

Cytokinesis is required to cleave the daughter cells at the end of mitosis and relies on the spatiotemporal control of RhoA GTPase. Cytokinesis failure can lead to changes in cell fate or aneuploidy, which can be detrimental during development and/or can le ...

Article GUID: 34405757


All-optical approaches to studying psychiatric disease

Author(s): Lafferty CK; Christinck TD; Britt JP;

Improvements in all-optical means of monitoring and manipulating neural activity have generated new ways of studying psychiatric disease. The combination of calcium imaging techniques with optogenetics to concurrently record and manipulate neural activity h ...

Article GUID: 34314828


Off-Target Influences of Arch-Mediated Axon Terminal Inhibition on Network Activity and Behavior.

Author(s): Lafferty CK, Britt JP

Front Neural Circuits. 2020;14:10 Authors: Lafferty CK, Britt JP

Article GUID: 32269514


Nucleus Accumbens Cell Type- and Input-Specific Suppression of Unproductive Reward Seeking.

Author(s): Lafferty CK, Yang AK, Mendoza JA, Britt JP

Cell Rep. 2020 Mar 17;30(11):3729-3742.e3 Authors: Lafferty CK, Yang AK, Mendoza JA, Britt JP

Article GUID: 32187545


Hippocampal Input to the Nucleus Accumbens Shell Enhances Food Palatability.

Author(s): Yang AK, Mendoza JA, Lafferty CK, Lacroix F, Britt JP

Biol Psychiatry. 2019 Sep 19;: Authors: Yang AK, Mendoza JA, Lafferty CK, Lacroix F, Britt JP

Article GUID: 31699294


Cue-Evoked Dopamine Neuron Activity Helps Maintain but Does Not Encode Expected Value.

Author(s): Mendoza JA, Lafferty CK, Yang AK, Britt JP

Cell Rep. 2019 Nov 05;29(6):1429-1437.e3 Authors: Mendoza JA, Lafferty CK, Yang AK, Britt JP

Article GUID: 31693885


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