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Discovery of an adjuvant that resensitizes polymyxin B-resistant bacteria

Author(s): Mahdavi M; Findlay BL;

Infections caused by antibiotic-resistant bacteria are a major threat to health, increasing mortality rates and straining health systems worldwide. Adjuvants targeted to beta-lactamase function are able to resensitize bacteria to beta-lactam antibiotics, bu ...

Article GUID: 38096681


Genome sequencing of 15 acid-tolerant yeasts

Author(s): Bagley JA; Pyne ME; Exley K; Kevvai K; Wang Q; Whiteway M; Martin VJJ;

We report draft genome sequences for 15 non-conventional Saccharomycotina yeast strains obtained from public culture repositories. Included in our collection are eight strains of Pichia with broad tolerance to dicarboxylic acids. The genome sequences of the ...

Article GUID: 37747226


Fitness Costs of Antibiotic Resistance Impede the Evolution of Resistance to Other Antibiotics

Author(s): Chowdhury FR; Findlay BL;

Antibiotic resistance is a major threat to global health, claiming the lives of millions every year. With a nearly dry antibiotic development pipeline, novel strategies are urgently needed to combat resistant pathogens. One emerging strategy is the use of s ...

Article GUID: 37726252


A resistome survey across hundreds of freshwater bacterial communities reveals the impacts of veterinary and human antibiotics use

Author(s): Kraemer SA; Barbosa da Costa N; Oliva A; Huot Y; Walsh DA;

Our decreasing ability to fight bacterial infections is a major health concern. It is arising due to the evolution of antimicrobial resistance (AMR) in response to the mis- and overuse of antibiotics in both human and veterinary medicine. Lakes integrate wa ...

Article GUID: 36338036


Phase Diagram for a Lysyl-Phosphatidylglycerol Analogue in Biomimetic Mixed Monolayers with Phosphatidylglycerol: Insights into the Tunable Properties of Bacterial Membranes.

Author(s): Wölk C, Youssef H, Guttenberg T, Marbach H, Vizcay-Barrena G, Shen C, Brezesinski G, Harvey RD ...

Ion pairing between the major phospholipids of the Staphylococcus aureus plasma membrane (phosphatidylglycerol - PG and lysyl-phosphatidylglycerol - LPG) confers resistance to antimicrobial peptide ...

Article GUID: 32065707


Arachidonic acid status negatively associates with forearm bone outcomes and glucose homeostasis in children with an overweight condition or obesity.

Author(s): Mak IL; Cohen TR; Vanstone CA; Weiler HA;

Long-chain polyunsaturated fatty acids are implicated in musculoskeletal health in adults. This study examined whether fatty acid status relates to bone health outcomes in children with overweight condition or obesity (body mass index z score, 3.1 ± 0.1; ag ...

Article GUID: 31269410


Antibiotic Pollution in the Environment: From Microbial Ecology to Public Policy.

Author(s): Kraemer SA, Ramachandran A, Perron GG

Microorganisms. 2019 Jun 22;7(6): Authors: Kraemer SA, Ramachandran A, Perron GG

Article GUID: 31234491


A comparison of the impact of physical exercise, cognitive training and combined intervention on spontaneous walking speed in older adults.

Author(s): Pothier K, Gagnon C, Fraser SA, Lussier M, Desjardins-Crépeau L, Berryman N, Kergoat MJ, Vu TTM, Li KZH, Bosquet L, Bherer L

Aging Clin Exp Res. 2018 Aug;30(8):921-925 Authors: Pothier K, Gagnon C, Fraser SA, Lussier M, Desjardins-Crépeau L, Berryman N, Kergoat MJ, Vu TTM, Li KZH, Bosquet L, Bherer L

Article GUID: 29235076


The effects of exercise on cognition and gait in Parkinson's disease: A scoping review.

Author(s): Intzandt B, Beck EN, Silveira CRA

Neurosci Biobehav Rev. 2018 12;95:136-169 Authors: Intzandt B, Beck EN, Silveira CRA

Article GUID: 30291852


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