Author(s): Pieruccini-Faria F; Son S; Zou G; Almeida QJ; Middleton LE; Bray NW; Lussier M; Shoemaker JK; Speechley M; Liu-Ambrose T; Burhan AM; Camicioli R; Li KZH; Fraser S; Berryman N; Bherer L; Montero-Odasso M;

Background: Older adults with mild cognitive impairment (MCI) have a higher risk of gait impairments and falls; yet, the effects of multimodal interventions, including combinations of exercises with cognitive training, on improving their mobility remain unclear. Objectives: To investigate the sy ...

Article GUID: 40966614

Author(s): Francavilla R; Chattopadhyaya B; Damo Kamda JL; Jadhav V; Kourrich S; Michaud JL; Di Cristo G;

SYNGAP1 haploinsufficiency-related intellectual disability (SYNGAP1-ID) is characterized by moderate to severe ID, generalized epilepsy, autism spectrum disorder, sensory processing dysfunction, and other behavioral abnormalities. While numerous studies have highlighted a role of Syngap1 in corti ...

Article GUID: 40810392

Author(s): Wang Z; Lyu L; Huang G; An C;

The increasing adoption of electric vehicles (EVs) is widely recognized as a pivotal strategy for mitigating climate change. However, the surge in EV usage brings significant challenges regarding the end-of-life management of lithium-ion batteries, particularly in geographically isolated islands, such as Vancouver Island, Canada. This study addresses the ...

Article GUID: 40795495

Author(s): Peng H; Hao J; Lyu L; Wan S; An C;

Industrial fishing's harmful subsidies fuel both a fish stock crisis and rising greenhouse gas emissions, even as calls for a global ban by the World Trade Organization persist amid slow progress. This study employs the framework of climate policy stringency assessment to examine fisheries subsidy reform through a carbon pricing lens. Using emissions, ...

Article GUID: 40737555

Author(s): Begum A; Uddin MA; Ahsan SM; Islam MA;

Background and aims: The rapid development and deployment of COVID-19 vaccines have been pivotal in the global battle against the pandemic. However, vaccine acceptance remains a critical determinant of their effectiveness. While numerous studies have explored factors influencing vaccine acceptance, there is a notable dearth of research regarding preferenc ...

Article GUID: 40687549

Author(s): Wu KY; Su ME; Kim Y; Nguyen L; Marchand M; Tran SD;

Wearable biosensors are revolutionizing the landscape of modern healthcare by enabling continuous, non-invasive monitoring and real-time diagnostics across a myriad of medical applications. This chapter provides a comprehensive overview of wearable biosensors, beginning with an exploration of their fundamental components, including biological elements, tr ...

Article GUID: 40683741

Author(s): Li Z; Luo Z; Bouguila N; Su W; Fan W;

Multi-view clustering has gained significant attention due to its ability to integrate data from diverse perspectives, frequently outperforming single-view approaches. However, existing methods often assume a Gaussian distribution within the latent embedding space, which can degrade performance when handling high-dimensional data or data with complex, non ...

Article GUID: 40664160

Author(s): Alves W; Babouras A; Martineau PA; Schutt D; Robbins S; Fevens T;

Concussions present a significant risk to athletes, with females exhibiting higher rates and prolonged recovery times than males. Current sideline concussion detection methods, such as the King-Devick test commonly used as a rapid screening tool designed to evaluate eye movement, attention, language, and cognitive processing abilities suffer from validity ...

Article GUID: 40632382

Author(s): Raheja Y; Singh V; Gaur VK; Sharma G; Tsang A; Chadha BS;

GH7 cellobiohydrolases (CBH1s) are essential for depolymerizing crystalline cellulose, yet the hypercellulolytic thermophile Rasamsonia emersonii secretes them only in low amounts, leaving a gap in its native enzyme cocktail. To see whether a cognate CBH1 could fill this gap and how it stacks up against the industrial workhorse strain Trichoderma reesei C ...

Article GUID: 40622460

Author(s): Silva MCJD; Pinto AMV; Balthar MA; Correa ABA; Bhattacharyya D; Simas ABC; Kuca K; Forgione P; França TCC; Cavalcante SFA; Kitagawa DAS;

Given the recent deployment of nerve agents as a method of warfare and in targeted assassinations, the development of robust, broad-spectrum medical countermeasures is essential. Our research group has synthesized isatin-pyridine oxime hybrids that have previously demonstrated the ability to resc ...

Article GUID: 40516590

Author(s): Yan B; Huang F; Ying J; Zhou D; Norouzi S; Zhang X; Wang B; Liu F;

Antibiotics are increasingly prevalent in global environments, driving antimicrobial resistance and disrupting microbial cycling. These impacts pose threats to human, animal, and environmental health. Therefore, addressing this emergent issue necessitates a One Health framework that integrates these interconnected dimensions. Here we systematically review ...

Article GUID: 40469481