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Are MEDLINE searches sufficient for systematic reviews and meta-analyses of the diagnostic accuracy of depression screening tools? A review of meta-analyses

Author(s): Rice DB; Kloda LA; Levis B; Qi B; Kingsland E; Thombs BD;

Objective: Database searches for studies of diagnostic test accuracy are notoriously difficult to filter, highly resource-intensive, and a potential barrier to quality evidence synthesis. We examined published meta-analyses of depression screening tool accu ...

Article GUID: 27411746


Reporting quality in abstracts of meta-analyses of depression screening tool accuracy: a review of systematic reviews and meta-analyses

Author(s): Rice DB; Kloda LA; Shrier I; Thombs BD;

Objective: Concerns have been raised regarding the quality and completeness of abstract reporting in evidence reviews, but this had not been evaluated in meta-analyses of diagnostic accuracy. Our objective was to evaluate reporting quality and completeness ...

Article GUID: 27864250


Depression Screening and Health Outcomes in Children and Adolescents: A Systematic Review

Author(s): Roseman M; Saadat N; Riehm KE; Kloda LA; Boruff J; Ickowicz A; Baltzer F; Katz LY; Patten SB; Rousseau C; Thombs BD; ...

Objective: Depression screening among children and adolescents is controversial. In 2009, the United States Preventive Services Task Force first recommended routine depression screening for adolesc ...

Article GUID: 28851234


Simultaneous automated ascertainment of prevalent vertebral fracture and abdominal aortic calcification in clinical practice: role in fracture risk assessment

Author(s): Schousboe JT; Lewis JR; Monchka BA; Reid SB; Davidson MJ; Kimelman D; Jozani MJ; Smith C; Sim M; Gilani SZ; Suter D; Leslie WD; ...

Whether simultaneous automated ascertainments of prevalent vertebral fracture (auto-PVFx) and abdominal aortic calcification (auto-AAC) on vertebral fracture assessment (VFA) lateral spine bone den ...

Article GUID: 38699950


Screening for parent and child ADHD in urban pediatric primary care: pilot implementation and stakeholder perspectives

Author(s): Lui JHL; Danko CM; Triece T; Bennett IM; Marschall D; Lorenzo NE; Stein MA; Chronis-Tuscano A; ...

Background: ADHD commonly co-occurs in children and parents. When ADHD is untreated in parents, it contributes to negative child developmental and treatment outcomes. Screening for parent and child ...

Article GUID: 37442955


A "biphasic glycosyltransferase high-throughput screen" identifies novel anthraquinone glycosides in the diversification of phenolic natural products

Author(s): Mohideen FI; Kwan DH;

The sugar moieties of many glycosylated small molecule natural products are essential for their biological activity. Glycosyltransferases (GTs) are the enzymes responsible for installing these sugar moieties on a variety of biomolecules. Several GTs that ar ...

Article GUID: 36682498


Microfluidics for long-term single-cell time-lapse microscopy: Advances and applications

Author(s): Allard P; Papazotos F; Potvin-Trottier L;

Cells are inherently dynamic, whether they are responding to environmental conditions or simply at equilibrium, with biomolecules constantly being made and destroyed. Due to their small volumes, the chemical reactions inside cells are stochastic, such that ...

Article GUID: 36312536


Transparency and completeness of reporting of depression screening tool accuracy studies: A meta-research review of adherence to the Standards for Reporting of Diagnostic Accuracy Studies statement

Author(s): Nassar EL; Levis B; Neyer MA; Rice DB; Booij L; Benedetti A; Thombs BD;

Objectives: Accurate and complete study reporting allows evidence users to critically appraise studies, evaluate possible bias, and assess generalizability and applicability. We evaluated the extent to which recent studies on depression screening accuracy w ...

Article GUID: 36047034


Perfluoroalkyl and polyfluoroalkyl substances (PFASs) in groundwater: current understandings and challenges to overcome

Author(s): Zhao Z; Li J; Zhang X; Wang L; Wang J; Lin T;

Perfluoroalkyl and polyfluoroalkyl substances (PFASs) have been frequently detected in groundwater globally. With the phase-out of perfluorooctane sulfonate (PFOS) and perfluorooctanate (PFOA) due to their risk to the ecosystem and human population, various ...

Article GUID: 35593984


Sample size and precision of estimates in studies of depression screening tool accuracy: A meta-research review of studies published in 2018-2021

Author(s): Nassar EL; Levis B; Neyer MA; Rice DB; Booij L; Benedetti A; Thombs BD;

Objectives: Depression screening tool accuracy studies should be conducted with large enough sample sizes to generate precise accuracy estimates. We assessed the proportion of recently published depression screening tool diagnostic accuracy studies that rep ...

Article GUID: 35362161


Inclusion of currently diagnosed or treated individuals in studies of depression screening tool accuracy: a meta-research review of studies published in 2018-2021

Author(s): Nassar EL; Levis B; Rice DB; Booij L; Benedetti A; Thombs BD;

Objectives: Screening is done to improve health outcomes by identifying and effectively treating individuals with unrecognized conditions. Depression screening has been proposed to identify previously unrecognized depression cases. Including individuals alr ...

Article GUID: 35334411


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