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Advanced Robotics for the Next-Generation of Cardiac Interventions

Author(s): Roshanfar M; Salimi M; Kaboodrangi AH; Jang SJ; Sinusas AJ; Wong SC; Mosadegh B;

With an increasing number of elderly individuals, the demand for advanced technologies to treat cardiac diseases has become more critical than ever. Additionally, there is a pressing need to reduce the learning curve for cardiac interventionalists to keep pace with the rapid development of new types of procedures and devices and to expand the adoption of ...

Article GUID: 40283240


An Effective and Fast Model for Characterization of Cardiac Arrhythmia and Congestive Heart Failure

Author(s): Lahmiri S; Bekiros S;

Background/Objectives: Cardiac arrhythmia (ARR) and congestive heart failure (CHF) are heart diseases that can cause dysfunction of other body organs and possibly death. This paper describes a fast and accurate detection system to distinguish between ARR and normal sinus (NS), and between CHF and NS. Methods: the proposed automatic detection system uses t ...

Article GUID: 40218199


Domains of wheelchair users socio-emotional experiences: Design insights from a scoping review

Author(s): Rasoulivalajoozi M; Cucuzzella C; Farhoudi M;

Background: Physical accessibility is not the only concern for wheelchair users (WUs); they also face barriers to social presence, such as challenges in social engagement and negative stereotypes. Identifying key domains in the literature that impact their social and emotional experiences is essential to addressing these issues. Objective: This scoping r ...

Article GUID: 40164524


Strategies to Reduce Uncertainties from the Best Available Physicochemical Parameters Used for Modeling Novel Organophosphate Esters across Multimedia Environments

Author(s): Xing C; Ge J; Chen R; Li S; Wang C; Zhang X; Geng Y; Jones KC; Zhu Y;

Organophosphate esters (OPEs) raise growing environmental and human health concerns globally. However, numerous novel OPEs lack data on physicochemical properties, which are essential for assessing environmental fate, exposure, and risks. This study predicted water solubility (Sw), vapor pressure (Vp), octanol-water partition coefficient (Kow), and octano ...

Article GUID: 40105294


A synthetic model of bioinspired liposomes to study cancer-cell derived extracellular vesicles and their uptake by recipient cells

Author(s): López RR; Ben El Khyat CZ; Chen Y; Tsering T; Dickinson K; Bustamante P; Erzingatzian A; Bartolomucci A; Ferrier ST; Douanne N; Mounier C; Stiharu I; Nerguizian V; Burnier JV;

Extracellular vesicles (EVs) are secreted by most cell types and play a central role in cell-cell communication. These naturally occurring nanoparticles have been particularly implicated in cancer, but EV heterogeneity and lengthy isolation methods with low yield make them difficult to study. To ...

Article GUID: 40069225


The Present and Future of Adult Entertainment: A Content Analysis of AI-Generated Pornography Websites

Author(s): Lapointe VA; Dubé S; Rukhlyadyev S; Kessai T; Lafortune D;

Fueled by advances in artificial intelligence (AI), the adult entertainment industry is undergoing a significant transformation. AI-generated pornography-or AI porn-is reshaping how people create and consume sexually explicit content, progressively offering rapid, mass access to large quantities of interactive and highly customizable experiences. Yet, des ...

Article GUID: 40032709


Spatial Variations of Atmospheric Alkylated Polycyclic Aromatic Hydrocarbons across the Western Pacific to the Southern Ocean: Unexpected Increasing Deposition

Author(s): Zhu FJ; Lu XM; Jia JW; Zhang X; Xing DF; Cai MH; Kallenborn R; Li YF; Muir DCG; Zhang ZF; Zhang X;

Spatial variations of atmospheric alkylated polycyclic aromatic hydrocarbons (Alk-PAHs) are key to understanding their long-range atmospheric transport (LRAT). However, limited Alk-PAHs data have hindered their LRAT characterizations on a global scale. In this study, 49 Alk-PAHs were measured in ...

Article GUID: 40025703


Elucidating the size distribution of p‑Phenylenediamine-Derived quinones in atmospheric particles

Author(s): Xia K; Qin M; Han M; Zhang X; Wu X; Liu M; Liu S; Wang X; Liu W; Xie Z; Yuan R; Liu Q;

Transformed from p-phenylenediamines (PPDs) antioxidant, PPD-derived quinones (PPD-Qs) have recently been recognized as emerging contaminants due to their potential negative impacts on the environment and human health. While there have been measurements of airborne PPD-Qs, the size distribution of PPD-Qs and the impact of particle size on PPD transformati ...

Article GUID: 39978217


Flow rate modulates focused ultrasound-mediated vascular delivery of microRNA

Author(s): He S; Singh D; Helfield B;

Gene therapy targeting ischemic heart disease is a promising therapeutic avenue, but it is mostly restricted to viral-based delivery approaches which are limited due to off-target immunological responses. Focused ultrasound presents a non-viral, image-guided technique in which circulating intravascular microbubble contrast agents can reversibly enhance va ...

Article GUID: 39850318


iSurgARy: A mobile augmented reality solution for ventriculostomy in resource-limited settings

Author(s): Asadi Z; Castillo JP; Asadi M; Sinclair DS; Kersten-Oertel M;

Global disparities in neurosurgical care necessitate innovations addressing affordability and accuracy, particularly for critical procedures like ventriculostomy. This intervention, vital for managing life-threatening intracranial pressure increases, is associated with catheter misplacement rates exceeding 30% when using a freehand technique. Such misplac ...

Article GUID: 39816703


Long-lasting antimicrobial effect of multipurpose ZnO nanoparticle-loaded dental resins enhanced by blue light photodynamic therapy

Author(s): Leite ML; Comeau P; Zaghwan A; Shen Y; Manso AP;

Objectives: This study aimed to assess the potential of experimental dental resins containing ZnO nanoparticles (ZnO-NPs) for antimicrobial photodynamic therapy (aPDT) as a functional tool for the modulation of cariogenic biofilm in long-term. Methods: Minimum inhibitory and bactericidal concentrations (MIC/MBC) of ZnO-NPs against Streptococcus mutans we ...

Article GUID: 39765362


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