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Peripheral inflammation in a Canadian cohort of neurodegenerative conditions: Occurrence, determinants, and impact

Author(s): Seixas-Lima B; Rosa-Neto P; Phillips NA; Borrie M; Roncero CT; Lahiri D; Dori D; Eintracht S; Chertkow H;

Background"Inflammaging" describes chronic low-grade inflammation observed in aging individuals. It may play a major role in neurodegeneration.ObjectiveTo assess blood inflammatory markers in older adults. We hypothesized that elevated inflammation would be found in some cognitively nor ...

Article GUID: 41358624


Longitudinal effects of cerebrovascular reactivity and cerebral pulsatility in cognitively intact older adults with APOE4: links with cognition

Author(s): Potvin-Jutras Z; Tremblay PL; Mohammadi H; Villeneuve S; Spreng RN; Gauthier CJ;

The apolipoprotein E4 (APOE4) allele is the strongest genetic risk factor for Alzheimer's disease (AD) and is linked to poorer cerebrovascular health. Cerebrovascular reactivity (CVR), an indicator of vascular reserve, and cerebral pulsatility (CP), a marker of vascular stiffness, are sensitive biomarkers of early vascular dysfunction associated with ...

Article GUID: 41353310


Strengthening community-based fisheries monitoring programs with Indigenous perspectives

Author(s): Dewan K; Mulrennan ME; Georgekish E;

Community-based monitoring (CBM) programs are increasingly recognized as essential for adaptive environmental stewardship. Yet, the CBM literature often highlights successful cases and privileges evaluations by external experts over those of community members themselves. To address this gap, we drew on insights from 23 semistructured interviews with Cree ...

Article GUID: 41332192


A comparison of municipal waste collection policies to optimize recycling rates: Evidence from England and Wales

Author(s): Wilansky J; Cao K;

This study investigated the effectiveness of municipal waste collection policies within England and Wales by examining how variations in local waste management strategies correlate with recycling rates. Using data from 297 council districts, we analysed the impact of different policy variables (frequency of residual waste and recycling collection, sorting ...

Article GUID: 41297338


A Deep Learning-Based Ensemble System for Brent and WTI Crude Oil Price Analysis and Prediction

Author(s): Zhang Y; Lahmiri S;

Crude oil price forecasting is an important task in energy management and storage. In this regard, deep learning has been applied in the literature to generate accurate forecasts. The main purpose of this study is to design an ensemble prediction system based on various deep learning systems. Specifically, in the first stage of our proposed ensemble syste ...

Article GUID: 41294965


We tried to become normal : Social class and memory in oral histories with Montreal Holocaust survivors

Author(s): Anna Sheftel

This article argues for social class and socioeconomic inequality as neglected forms of analysis when studying the memories and narratives of Holocaust survivors. Based primarily in oral histories conducted with Holocaust survivors in Montreal, this argument is elaborated in two ways. First, the author demonstrates stories that have been left out of Holoc ...

Article GUID: 41281595


Weight bias, stigma and discrimination: a call for greater conceptual clarity

Author(s): Côté M; Forouhar V; Sacco S; Baillot A; Himmelstein M; Hussey B; Incollingo Rodriguez AC; Nagpal TS; Nutter S; Patton I; Pearl RL; Puhl RM; Ramos Salas X; Russell-Mayhew S; Alberga AS;

Article GUID: 41280193


From pollution barriers to health buffers: Rethinking building airtightness under climate variability

Author(s): Fu N; Zhang R; Haghighat F; Kumar P; Cao SJ;

Climate change is reshaping indoor-outdoor pollution dynamics, yet current building standards rarely reflect this shift. In rapidly urbanizing regions with high ambient PM2.5 levels, building airtightness offers an underutilized strategy to mitigate indoor exposure and associated health burdens. An analysis of 36 major Chinese cities across five climate z ...

Article GUID: 41252997


Methotrexate plus low-dose prednisolone compared with high-dose corticosteroid therapy in the management of idiopathic granulomatous mastitis

Author(s): Shojaee L; Nafissi N; Roodposhti FN; Shakeriastani K; Shakeriastani K;

Purpose: Idiopathic granulomatous mastitis (IGM) is a chronic, relapsing inflammatory breast disease of unknown etiology. Its unpredictable course and unclear pathogenesis have made treatment a persistent clinical challenge. This study aimed to evaluate treatment outcomes in patients with IGM, focusing on extending remission periods and reducing relapse r ...

Article GUID: 41251719


Imagining the beat: causal evidence for dorsal premotor cortex (dPMC) role in beat imagery via transcranial magnetic stimulation (TMS)

Author(s): Lazzari G; Ferreri L; Cattaneo L; Penhune V; Lega C;

The ability to internally generate and maintain a rhythmic pulse, i.e., beat imagery, is a fundamental aspect of musical cognition. While recent theories propose that premotor regions support internal temporal predictions during rhythm perception and imagery, direct causal evidence remains limited. In this study, we investigated the specific contributions ...

Article GUID: 41248776


From water to sediment: A meta-analysis of microplastic distribution and the impact of dams in reservoir ecosystems

Author(s): Gao W; Zhang P; Wang H; Yang X; An C;

Microplastics (MPs) have become major contaminants in freshwater ecosystems. While numerous studies have characterized MPs in reservoirs, a comprehensive synthesis focusing on in-reservoir variations and dam-related influences is still lacking. This study investigates the spatial distribution of MPs in reservoir water and sediment based on data synthesize ...

Article GUID: 41215774


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