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Functional and structural characterization of an IclR family transcription factor for the development of dicarboxylic acid biosensors

Author(s): Pham C; Nasr MA; Skarina T; Di Leo R; Kwan DH; Martin VJJ; Stogios PJ; Mahadevan R; Savchenko A; ...

Prokaryotic transcription factors (TFs) regulate gene expression in response to small molecules, thus representing promising candidates as versatile small molecule-detecting biosensors valuable for ...

Article GUID: 38696354


Advancement in Biosensor Technologies of 2D MaterialIntegrated with Cellulose-Physical Properties

Author(s): Ramezani G; Stiharu I; van de Ven TGM; Nerguizian V;

This review paper provides an in-depth analysis of recent advancements in integrating two-dimensional (2D) materials with cellulose to enhance biosensing technology. The incorporation of 2D materials such as graphene and transition metal dichalcogenides, al ...

Article GUID: 38258201


A Synthetic Biosensor for Detecting Putrescine in Beef Samples

Author(s): Selim AS; Perry JM; Nasr MA; Pimprikar JM; Shih SCC;

Biogenic amines (BAs) are toxicological risks present in many food products. Putrescine is the most common foodborne BA and is frequently used as a quality control marker. Currently, there is a lack of regulation concerning safe putrescine limits in food as ...

Article GUID: 36356104


A Versatile Transcription Factor Biosensor System Responsive to Multiple Aromatic and Indole Inducers

Author(s): Nasr MA; Timmins LR; Martin VJJ; Kwan DH;

Allosteric transcription factor (aTF) biosensors are valuable tools for engineering microbes toward a multitude of applications in metabolic engineering, biotechnology, and synthetic biology. One of the challenges toward constructing functional and diverse ...

Article GUID: 35316041


Defective GaAs nanoribbon-based biosensor for lung cancer biomarkers: a DFT study

Author(s): Tarun T; Singh P; Kaur H; Walia GK; Randhawa DKK; Choudhary BC;

Density functional theory-based first-principles investigation is performed on pristine and mono vacancy induced GaAs nanoribbons to detect the presence of three volatile organic compounds (VOCs), aniline, isoprene and o-toluidine, which will aid in sensing ...

Article GUID: 34459994


Seeing is believing: tools to study the role of Rho GTPases during cytokinesis

Author(s): Koh SP; Pham NP; Piekny A;

Cytokinesis is required to cleave the daughter cells at the end of mitosis and relies on the spatiotemporal control of RhoA GTPase. Cytokinesis failure can lead to changes in cell fate or aneuploidy, which can be detrimental during development and/or can le ...

Article GUID: 34405757


Recent Advances of DNA Tetrahedra for Therapeutic Delivery and Biosensing.

Author(s): Copp W, Pontarelli A, Wilds CJ

The chemical and self-assembly properties of nucleic acids make them ideal for the construction of discrete structures and stimuli-responsive devices for a diverse array of applications. Amongst the various three-dimensional assemblies, DNA tetrahedra are o ...

Article GUID: 33506614


Finite Element Modelling of Bandgap Engineered Graphene FET with the Application in Sensing Methanethiol Biomarker.

Author(s): Singh P, Abedini Sohi P, Kahrizi M

In this work, we have designed and simulated a graphene field effect transistor (GFET) with the purpose of developing a sensitive biosensor for methanethiol, a biomarker for bacterial infections. The surface of a graphene layer is functionalized by manipula ...

Article GUID: 33467459


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