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Beyond ribose and phosphate: Selected nucleic acid modifications for structure-function investigations and therapeutic applications

Author(s): Liczner C; Duke K; Juneau G; Egli M; Wilds CJ;

Over the past 25 years, the acceleration of achievements in the development of oligonucleotide-based therapeutics has resulted in numerous new drugs making it to the market for the treatment of various diseases. Oligonucleotides with alterations to their sc ...

Article GUID: 33981365


An efficient method for indexing grazing-incidence X-ray diffraction data of epitaxially grown thin films

Author(s): Simbrunner J; Schrode B; Domke J; Fritz T; Salzmann I; Resel R;

Crystal structure identification of thin organic films entails a number of technical and methodological challenges. In particular, if molecular crystals are epitaxially grown on single-crystalline substrates a complex scenario of multiple preferred orientat ...

Article GUID: 32356785


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