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Stability of Acetals/Ketals Under Controlled Radical and Ring Opening Polymerization

Author(s): Andrade-Gagnon B; Casillas-Popova SN; Oh JK;

Well-defined acid-degradable amphiphilic block copolymers (ABPs) and their nanoassemblies labeled with acid-labile groups have been developed for smart drug delivery, exhibiting controlled/enhanced release of therapeutics in tumoral tissues and endo/lysosomes. In general, controlled polymerization techniques, particularly atom transfer radical polymerizat ...

Article GUID: 40614241


Enhanced biodegradation of crude oil by phosphate-solubilizing bacteria Bacillus subtilis PSB-1: Overcoming soluble phosphorus deficiency

Author(s): Wang X; Du Z; Li Z; Liu M; Mu J; Feng L; Chen Z; Chen Q;

Due to the oligotrophic marine environment, the lack of phosphorus is one of the key factors limiting the oil biodegradation ability of microorganisms after the oil spill occurs. Overcoming phosphorus deficiency has become an urgent problem. In this study, a phosphate-solubilizing bacteria, named Bacillus subtilis PSB-1, with the crude oil degradation eff ...

Article GUID: 40609441


Application of machine learning for predicting the incubation period of water droplet erosion in metals

Author(s): AlHammad K; Medraj M; Tembely M;

Water droplet erosion (WDE) is a critical degradation phenomenon that significantly affects component lifespan and performance in power generation, aerospace, and wind energy industries. The incubation period-the initial phase before visible material loss occurs-is particularly crucial for maintenance planning and material selection yet remains challengin ...

Article GUID: 40612685


Upconversion Lanthanide-Based 2D Metal-Organic Frameworks for Multimode Information Encryption

Author(s): Chen J; Xie Y; Yang W; Sun R; Xing F; Mandl GA; Capobianco JA; Sun L;

Luminescent 2D metal-organic frameworks (MOFs) are a class of metal-organic framework materials expanded in a 2D plane, which have a wide range of applications in fields of optoelectronic devices, sensors, and information storage due to their unique layered structure and excellent optical properties. Currently, research on luminescent 2D MOFs mainly focus ...

Article GUID: 40557752


Contextual variations in the effects of social withdrawal, peer exclusion, and friendship on growth curves of depressed affect in late childhood

Author(s): Commisso M; Persram RP; Lopez LS; Bukowski WM;

The moderating roles of friendship and contextual variables on associations between social withdrawal and peer exclusion and growth curves of depressed affect were studied with a three-wave multilevel longitudinal design. Participants were 313 boys and girls aged 10-12 from Canada (n = 139), mostly of European and North African descent, and Colombia (n = ...

Article GUID: 40583455


PARPAL: PARalog Protein Redistribution using Abundance and Localization in Yeast Database

Author(s): Greco BM; Zapata G; Dandage R; Papkov M; Pereira V; Lefebvre F; Bourque G; Parts L; Kuzmin E;

Whole-genome duplication (WGD) events are common across various organisms; however, the retention and evolution of WGD paralogs is not fully understood. Quantitative measure of protein redistribution in response to the deletion of their WGD paralog provides insight into sources of gene retention. ...

Article GUID: 40580499


No species left behind: borrowing strength to map data-deficient species

Author(s): Sharma S; Winner K; Pollock LJ; Thorson JT; Mäkinen J; Merow C; Pedersen EJ; Chefira KF; Portmann JM; Iannarilli F; Beery S; de Lutio R; Jetz W;

We lack the data needed to detect and understand biodiversity change for most species, despite some species having millions of observations. This unequal data coverage impedes conservation planning and our understanding of biodiversity patterns. The 'borrowing strength' approach leverages ...

Article GUID: 40571432


Comprehensive review of reinforcement learning for medical ultrasound imaging

Author(s): Elmekki H; Islam S; Alagha A; Sami H; Spilkin A; Zakeri E; Zanuttini AM; Bentahar J; Kadem L; Xie WF; Pibarot P; Mizouni R; Otrok H; Singh S; Mourad A;

Medical Ultrasound (US) imaging has seen increasing demands over the past years, becoming one of the most preferred imaging modalities in clinical practice due to its affordability, portability, and real-time capabilities. However, it faces several challenges that limit its applicability, such as ...

Article GUID: 40567264


Hearing loss is associated with decreased default-mode network connectivity in individuals with mild cognitive impairment

Author(s): Grant N; Phillips N;

Mild cognitive impairment (MCI) and hearing loss (HL) have been separately associated with increased dementia risk. These highly co-occurring dementia risk factors are associated with aberrant functional brain connectivity. In individuals with HL aberrant functional connectivity has been associated with cognitive impairment. In individuals with MCI, aberr ...

Article GUID: 40567819


Is Adipose Tissue Inflammation the Culprit of Obesity-Associated Comorbidities?

Author(s): Turner L; Wanasinghe AI; Brunori P; Santosa S;

In individuals with obesity, the onset of chronic comorbidities coincides with the excessive accumulation of adipose tissue in various tissue beds. As obesity progresses, adipose tissue becomes increasingly dysfunctional causing chronic low-grade inflammation. Indeed, adipose tissue inflammation, which partially stems from macrophage infiltration and expr ...

Article GUID: 40533358


In vitro evaluation of isatin-pyridine oxime hybrids as potential acetylcholinesterase inhibitors for nerve agent prophylaxis

Author(s): Silva MCJD; Pinto AMV; Balthar MA; Correa ABA; Bhattacharyya D; Simas ABC; Kuca K; Forgione P; França TCC; Cavalcante SFA; Kitagawa DAS;

Given the recent deployment of nerve agents as a method of warfare and in targeted assassinations, the development of robust, broad-spectrum medical countermeasures is essential. Our research group has synthesized isatin-pyridine oxime hybrids that have previously demonstrated the ability to resc ...

Article GUID: 40516590


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