Author(s): Tikoo S; Noronha AM; Wilds CJ;
In this study, we report the synthesis of an alkylene linker containing a terminal 2-cyanoethyl protected selenium functionality for coupling at the 5'-end of an oligonucleotide by solid phase synthesis for the preparation of oligonucleotide conjugates. Upon deprotection and cleavage from the solid support, quantitative formation of a 5'-diselenid ...
Article GUID: 42322227
Author(s): Perovic M; Phillips NA; Einstein G;
Introduction: Women make up two-thirds of people with Alzheimer's disease (AD). Research has focused on biological explanations for this sex difference, while contributions of psychosocial risk factors are less well understood. Methods: We examined sex differences in the effects of adverse childhood experiences (ACEs) on late-life cognition in groups ...
Article GUID: 42325010
Author(s): Oliviera P; Maye F; Turak A;
Small-molecule π $\pi$ -conjugated semiconductors provide an ordered platform for probing interfacial mechanisms in organic optoelectronics, where device performance and stability are dominated by interface effects. Lithium fluoride, despite its widespread use as an interlayer, remains paradoxical: essential for high device efficiencies yet governe ...
Article GUID: 42316423
Author(s): Wikberg EC; Lucci S; Glotfelty E; Campos F; Sicotte P;
Winners of aggressive intergroup encounters are often assumed to benefit from increased access to resources, but few studies have measured whether there is differential access to resources based on the intergroup outcome. To investigate whether winning intergroup encounters is associated with increased access to food, we used 13 months of data on intergro ...
Article GUID: 42310246
Author(s): Petrossian G; Diouri Y; Xu B; Ebrahimi S; Pande A; Miquet-Westphal F; Xu H; Cicoira F;
Soft, conductive materials that simultaneously offer mechanical compliance, electrical conductivity, recyclability, and scalable manufacturing remain difficult to achieve. Here, we introduce recyclable, 3D-printable PEDOT:PSS syntactic foams based on polymer microspheres coated in situ, enabling precise control over porosity, mechanical properties, and el ...
Article GUID: 42310993
Author(s): Rasoulivalajoozi M; Farhoudi M;
Purpose: Wheelchairs should support not only safe and intuitive navigation but also positive social presence without reinforcing disability-related stereotypes. This study introduces a user-centred external communication framework (ECF) to guide the design of wheelchair external human-machine interfaces and their perceptual dimensions.Materials and method ...
Article GUID: 42300838
Author(s): Nikolic M; Caswell CB; Prada NP; Iqbal M; Cox SML; Jaworska N; Castellanos-Ryan N; Vitaro F; Brendgen M; Parent S; Boivin M; Côté S; Tremblay RE; Séguin JR; Leyton M;
Background: We recently reported evidence that a biopsychosocial model predicts lifetime histories of commonly comorbid early-onset psychiatric disorders. This transdiagnostic model was produced when incorporating either positron emission tomography-measured midbrain dopamine autoreceptors or fun ...
Article GUID: 42293407
Author(s): Wu N; Joyal-Desmarais K; Linkins LA; Flórez ID; Bacon SL;
Background: The COVID-19 pandemic demanded evidence synthesis approaches that could keep pace with rapidly evolving science and urgent policy needs. Rapid reviews and living evidence syntheses (LES) emerged as critical methodological responses, yet limited guidance exists for teams undertaking such work, particularly regarding the operational challenges o ...
Article GUID: 42282099
Author(s): David LeRue
This practitioner reflection examines how painting in plein-air-meaning outdoors from life-inspired multimodal fieldnotes that became the node between research, teaching, and place. This work was conducted during a 4-year, community-engaged art education study where the community art classroom was employed to develop participatory arts-based research meth ...
Article GUID: 42273064
Author(s): Brusseau AJP; Synnott FD; Nagl A; Morris J; Mathis A; Ramnarine IW; Crane AL; Brown GE;
Males and females, especially in species with more pronounced sexual dimorphisms, may face very different trade-offs between detecting and avoiding predation threats and the need to court potential mates. Within aquatic ecosystems, the use of reliable publicly available chemosensory risk assessment cues allows prey to assess local threats and optimize the ...
Article GUID: 42264418
Author(s): Delaney KZ; Nadeem MI; Plissonneau C; Khor N; Delaney J; Morais JA; Tsoukas MA; Pescarus R; Garneau PY; Santosa S;
Adipose tissue (AT) immune cells are implicated in the pathology of type 2 diabetes (T2D), and their content likely differs between abdominal subcutaneous adipose tissue (abSAT), femoral SAT (fmSAT), and visceral adipose tissue (VAT). Therefore, the objective of the current study was to develop a ...
Article GUID: 42255513
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