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Expansion of Auxiliary Activity Family 5 sequence space via biochemical characterization of six new copper radical oxidases

Author(s): Fong JK; Mathieu Y; Vo MT; Bellemare A; Tsang A; Brumer H;

Bacterial and fungal copper radical oxidases (CROs) from Auxiliary Activity Family 5 (AA5) are implicated in morphogenesis and pathogenesis. The unique catalytic properties of CROs also make these enzymes attractive biocatalysts for the transformation of sm ...

Article GUID: 38953370


Functional and structural characterization of an IclR family transcription factor for the development of dicarboxylic acid biosensors

Author(s): Pham C; Nasr MA; Skarina T; Di Leo R; Kwan DH; Martin VJJ; Stogios PJ; Mahadevan R; Savchenko A; ...

Prokaryotic transcription factors (TFs) regulate gene expression in response to small molecules, thus representing promising candidates as versatile small molecule-detecting biosensors valuable for ...

Article GUID: 38696354


Family dysfunction, stressful life events, and mental health problems across development in the offspring of parents with an affective disorder

Author(s): Resendes T; Ellenbogen MA; Oldehinkel AJ;

Background: Offspring of parents with affective disorders (OAD) are at risk of developing a wide range of mental disorders. Deficits in the rearing environment and high levels of stress are well-known risk factors for negative outcomes in OAD. Building on p ...

Article GUID: 38682166


From Compliance to Care: Qualitative Findings from a Survey of Essential Caregivers in Ontario Long-Term Care Homes

Author(s): Conklin J; Dehcheshmeh MM; Archibald D; Elliott J; Hsu A; Kothari A; Stolee P; Sveistrup H; ...

Background: The COVID-19 pandemic highlighted the importance of the care provided by family members and close friends to older people living in long-term care (LTC) homes. Our implementation scienc ...

Article GUID: 38561989


Substrate specificity mapping of fungal CAZy AA3_2 oxidoreductases

Author(s): Zhao H; Karppi J; Mototsune O; Poshina D; Svartström J; Nguyen TTM; Vo TM; Tsang A; Master E; Tenkanen M; ...

Background: Oxidative enzymes targeting lignocellulosic substrates are presently classified into various auxiliary activity (AA) families within the carbohydrate-active enzyme (CAZy) database. Amon ...

Article GUID: 38539167


Intersection of Intimate Partner Violence, Partner Interference, and Family Supportive Supervision on Victims' Work Withdrawal

Author(s): Isola C; Granger S; Turner N; LeBlanc MM; Barling J;

This study investigates the link between intimate partner violence (IPV) and work withdrawal (including absence frequency, partial absenteeism, and turnover intentions) in the context of partners' interference with victims at work and family supportive ...

Article GUID: 37359457


Characterization and Expression of the Pirin Gene Family in Triticum aestivum

Author(s): Brunetti SC; Arseneault MKM; Gulick PJ;

Pirins are nuclear bicupin proteins, encoded by genes that are one of several gene families that comprise the Cupin superfamily in plants. Pirin genes have been implicated in stress response pathways studied in Arabidopsis and At-Pirin1 has been shown to in ...

Article GUID: 35504035


Characterization of the heterotrimeric G protein gene families in Triticum aestivum and related species

Author(s): Gawande ND; Hamiditabar Z; Brunetti SC; Gulick PJ;

This study characterizes the heterotrimeric G protein gene families in Triticum aestivum, their tissue-specific expression patterns during development and in response to biotic and abiotic stress conditions. There are three Ga genes, three Gß and 12 G? gene ...

Article GUID: 35463045


Screening of novel fungal Carbohydrate Esterase family 1 enzymes identifies three novel dual feruloyl/acetyl xylan esterases

Author(s): Dilokpimol A; Verkerk B; Li X; Bellemare A; Lavallee M; Frommhagen M; Nørmølle Underlin E; Kabel MA; Powlowski J; Tsang A; de Vries RP; ...

Feruloyl esterases (FAEs) and acetyl xylan esterases (AXEs) are important enzymes for plant biomass degradation and are both present in Carbohydrate Esterase family 1 (CE1) of the Carbohydrate-Acti ...

Article GUID: 35187647


Conflict Resolution and Emotional Expression in Sibling and Mother-Adolescent Dyads: Within-Family and Across-Context Similarities

Author(s): Ferrar SJ; Stack DM; Baldassarre KS; Orsini A; Serbin LA;

Early adolescents (aged 12-15) were observed during dyadic conflict discussions with their siblings (n = 23) and mothers (n = 32) in their homes. The verbal conflict behaviors and affect of family members were coded continuously. Sequential analyses identif ...

Article GUID: 35103031


Family Members' Perceptions of Their Psychological Responses One Year Following Pediatric Intensive Care Unit (PICU) Hospitalization: Qualitative Findings From the Caring Intensively Study

Author(s): Rennick JE; Knox AM; Treherne SC; Dryden-Palmer K; Stremler R; Chambers CT; McRae L; Ho M; Stack DM; Dougherty G; Fudge H; Campbell-Yeo M; ...

ntroduction: PICU hospitalization can have a profound impact on child survivors and their families. There is limited research on children's long-term recovery within the context of the family f ...

Article GUID: 34557460


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