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NMDA Receptors in the Basolateral Amygdala Complex Are Engaged for Pavlovian Fear Conditioning When an Animal's Predictions about Danger Are in Error

Author(s): Tuval Keidar

It is widely accepted that Pavlovian fear conditioning requires activation of NMDA receptors (NMDARs) in the basolateral amygdala complex (BLA). However, it was recently shown that activation of NMDAR in the BLA is only required for fear conditioning when d ...

Article GUID: 37607821


Danger Changes the Way the Brain Consolidates Neutral Information; and Does So by Interacting with Processes Involved in the Encoding of That Information

Author(s): Omar A Qureshi

This study examined the effect of danger on consolidation of neutral information in two regions of the rat (male and female) medial temporal lobe: the perirhinal cortex (PRh) and basolateral amygdala complex (BLA). The neutral information was the associatio ...

Article GUID: 36927572


Alarm cues and alarmed conspecifics: neural activity during social learning from different cues in Trinidadian guppies

Author(s): Raina Fan

Learning to respond appropriately to novel dangers is often essential to survival and success, but carries risks. Learning about novel threats from others (social learning) can reduce these risks. Many species, including the Trinidadian guppy (Poecilia reti ...

Article GUID: 36043284


Prediction error determines whether NMDA receptors in the basolateral amygdala complex are involved in Pavlovian fear conditioning

Author(s): Williams-Spooner MJ; Delaney AJ; Westbrook RF; Holmes NM;

It is widely accepted that activation of N-methyl-D-aspartate receptors (NMDAR) is necessary for the formation of fear memories in the basolateral amygdala complex (BLA). This acceptance is based on findings that blockade of NMDAR in the BLA disrupts Pavlov ...

Article GUID: 35410880


Mechanisms of higher-order learning in the amygdala

Author(s): Gostolupce D; Iordanova MD; Lay BPP;

Adaptive behaviour is under the potent control of environmental cues. Such cues can acquire value by virtue of their associations with outcomes of motivational significance, be they appetitive or aversive. There are at least two ways through which an enviro ...

Article GUID: 34197867


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