Author(s): Pontarelli A; Wilds CJ;
The introduction of chemical modifications on the nucleic acid scaffold has allowed for the progress of antisense oligonucleotides (ASOs) in the clinic for the treatment of a variety of disorders. In contribution to the repertoire of gene-silencing nucleic ...
Article GUID: 36857293
Author(s): Pontarelli A; Wilds CJ;
The promise of the antisense approach to treat a variety of diseases with oligonucleotides and solutions to challenges that have been encountered in their development is attributable to chemical modification of the nucleic acid scaffold. Herein, we describe ...
Article GUID: 35452799
Author(s): Copp W, Pontarelli A, Wilds CJ
The chemical and self-assembly properties of nucleic acids make them ideal for the construction of discrete structures and stimuli-responsive devices for a diverse array of applications. Amongst the various three-dimensional assemblies, DNA tetrahedra are o ...
Article GUID: 33506614
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