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Insomnia symptoms among older adults during the first year of the COVID-19 pandemic: A longitudinal study

Author(s): Gong K; Garneau J; Grenier S; Vasiliadis HM; Dang-Vu TT; Dialahy IZ; Gouin JP;

Objective: To identify sociodemographic, psychological, and health factors related to trajectories of insomnia symptoms in older adults during the COVID-19 pandemic. Methods: From May 2020 to May 2021, 644 older adults (mean age = 78.73, SD = 5.60) complet ...

Article GUID: 37380593


Two Chemical Engineers Look at the COVID-19 Pandemic

Author(s): De Visscher A; Pinheiro PatrĂ­cio PC;

Chemical engineering involves a skill set that is transferrable to a broad range of other areas. A case in point is the work that is being done by chemical engineers to better understand and fight the COVID-19 epidemic. In this study, we consider a problem ...

Article GUID: 35942051


Evaluating SARS-CoV-2 airborne quanta transmission and exposure risk in a mechanically ventilated multizone office building

Author(s): Yan S; Wang LL; Birnkrant MJ; Zhai J; Miller SL;

The world has faced tremendous challenges during the COVID-19 pandemic since 2020, and effective clean air strategies that mitigate infectious risks indoors have become more essential. In this study, a novel approach based on the Wells-Riley model applied t ...

Article GUID: 35602249


Predicted coronavirus Nsp5 protease cleavage sites in the human proteome

Author(s): Scott BM; Lacasse V; Blom DG; Tonner PD; Blom NS;

Background: The coronavirus nonstructural protein 5 (Nsp5) is a cysteine protease required for processing the viral polyprotein and is therefore crucial for viral replication. Nsp5 from several coronaviruses have also been found to cleave host proteins, dis ...

Article GUID: 35379171


COVID-19-Related Concerns and Symptoms of Anxiety: Does Concern Play a Role in Predicting Severity and Risk?

Author(s): Benzouak T; Gunpat S; Briner EL; Thake J; Kisely S; Rao S;

Objective Rates of anxiety have increased during the coronavirus disease 2019 (COVID-19) pandemic, partially attributable to the experience of COVID-19 related concerns. It remains pivotal to determine the implications of such concerns on the severity of an ...

Article GUID: 34987892


Removal of SARS-CoV-2 using UV+Filter in built environment: simulation/evaluation by utilizing validated numerical method

Author(s): Feng Z; Cao SJ; Haghighat F;

Air cleaning is an effective and reliable method in indoor airborne SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona-Virus 2) control, with ability of aerosol removal or disinfection. However, traditional air cleaning systems (e.g. fibrous filter, elect ...

Article GUID: 34367884


Structure-Based Virtual Screening Reveals Ibrutinib and Zanubrutinib as Potential Repurposed Drugs against COVID-19

Author(s): Kaliamurthi S; Selvaraj G; Selvaraj C; Singh SK; Wei DQ; Peslherbe GH;

Coronavirus disease (COVID)-19 is the leading global health threat to date caused by a severe acute respiratory syndrome coronavirus (SARS-CoV-2). Recent clinical trials reported that the use of Bruton's tyrosine kinase (BTK) inhibitors to treat COVID-1 ...

Article GUID: 34209188


Exploring the Role of Glycans in the Interaction of SARS-CoV-2 RBD and Human Receptor ACE2

Author(s): Nguyen K; Chakraborty S; Mansbach RA; Korber B; Gnanakaran S;

COVID-19 is a highly infectious respiratory disease caused by the novel coronavirus SARS-CoV-2. It has become a global pandemic and its frequent mutations may pose new challenges for vaccine design. During viral infection, the Spike RBD of SARS-CoV-2 binds ...

Article GUID: 34067878


Are the Allergic Reactions of COVID-19 Vaccines Caused by mRNA Constructs or Nanocarriers? Immunological Insights

Author(s): Selvaraj G; Kaliamurthi S; Peslherbe GH; Wei DQ;

The Food and Drug Administration (FDA) has recently authorized the two messenger RNA (mRNA) vaccines BNT162b2 and mRNA-1273 for emergency use against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the COVID-19 coronavirus disease. ...

Article GUID: 34021862


Tools and Techniques for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/COVID-19 Detection

Author(s): Safiabadi Tali SH; LeBlanc JJ; Sadiq Z; Oyewunmi OD; Camargo C; Nikpour B; Armanfard N; Sagan SM; Jahanshahi-Anbuhi S; ...

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and deaths worldwide. Efficient diagn ...

Article GUID: 33980687


Indoor airborne disinfection with electrostatic disinfector (ESD): Numerical simulations of ESD performance and reduction of computing time

Author(s): Feng Z; Cao SJ; Wang J; Kumar P; Haghighat F;

Airborne transmissions of infectious disease (e.g. SARS-CoV-2) in indoor environments may induce serious threat to public health. Air purification devices are necessary to remove and/or inactivate airborne biological species from indoor air environment. Cor ...

Article GUID: 33994653


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