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Predicting response to stepped-care cognitive behavioral therapy for insomnia using pre-treatment heart rate variability in cancer patients

Author(s): Garneau J; Savard J; Dang-Vu TT; Gouin JP;

Objective: This study examined whether high frequency heart-rate variability (HF-HRV) and HF-HRV reactivity to worry moderate response to cognitive behavioural therapy for insomnia (CBT-I) within both a standard and stepped-care framework among cancer patie ...

Article GUID: 38991424


Cardiac gene delivery using ultrasound: State of the field

Author(s): Singh D; Memari E; He S; Yusefi H; Helfield B;

Over the past two decades, there has been tremendous and exciting progress toward extending the use of medical ultrasound beyond a traditional imaging tool. Ultrasound contrast agents, typically used for improved visualization of blood flow, have been explo ...

Article GUID: 38983873


A randomized controlled trial of an acceptance-based, insight-inducing medication adherence therapy (AIM-AT) for adults with early-stage psychosis

Author(s): Chien WT; Chong YY; Bressington D; McMaster CW;

This study aimed to test the effectiveness of an acceptance-based medication adherence intervention for people with early-stage psychosis. An assessor-blind, three-arm randomized controlled trial design was used. One hundred and twenty-six participants who ...

Article GUID: 38908265


A pan-theoretical conceptualization of client involvement in psychotherapy

Author(s): Morris E; Fitzpatrick MR; Renaud J;

Objective: The present paper attempts to differentiate client involvement from other, similar process variables and presents a pan-theoretical conceptualization of client involvement. Method: A modified Delphi poll was conducted with 20 experienced clinici ...

Article GUID: 25017441


Exploring patterns in mental health treatment and interests of single adults in the United States: a secondary data analysis

Author(s): Gesselman AN; Kaufman EM; Weeks LYS; Moscovici Z; Bennett-Brown M; Adams OR; Campbell JT; Piazza M; Bhuyan L; Dubé S; Hille JJ; Garcia JR; ...

Objective: The objective of this study is to examine mental health treatment utilization and interest among the large and growing demographic of single adults in the United States, who face unique ...

Article GUID: 38711766


Discovery and preclinical development of a therapeutically active nanobody-based chimeric antigen receptor targeting human CD22

Author(s): McComb S; Arbabi-Ghahroudi M; Hay KA; Keller BA; Faulkes S; Rutherford M; Nguyen T; Shepherd A; Wu C; Marcil A; Aubry A; Hussack G; Pinto DM ...

Chimeric antigen receptor (CAR) T cell therapies targeting B cell-restricted antigens CD19, CD20, or CD22 can produce potent clinical responses for some B cell malignancies, but relapse remains com ...

Article GUID: 38596311


The effects of intranasal oxytocin on the efficacy of psychotherapy for major depressive disorder: a pilot randomized controlled trial

Author(s): Ellenbogen MA; Cardoso C; Serravalle L; Vadaga K; Joober R;

Background: Although both pharmacotherapy and psychological treatments are considered to be efficacious in the treatment of major depressive disorder (MDD), one third of patients do not respond to treatment and many experience residual symptoms post-treatme ...

Article GUID: 38445382


Antimicrobial photodynamic therapy against a dual-species cariogenic biofilm using a ruthenium-loaded resin-based dental material

Author(s): Leite ML; Comeau P; Aghakeshmiri S; Lange D; Rodrigues LKA; Branda N; Manso AP;

Background: Streptococcus mutans and Candida albicans are associated with caries recurrence. Therefore, this study evaluated the combination of a Ru(II)-loaded resin-based dental material (RDM) and antimicrobial photodynamic therapy (aPDT) against a dual-sp ...

Article GUID: 38395246


The effect of Wharton's jelly-derived stem cells seeded/boron-loaded acellular scaffolds on the healing of full-thickness burn wounds in the rat model

Author(s): Nikzad S; Same S; Safiri S; Dolati S; Roushangar Zineh B; Meshgi S; Roshangar L; Sahin F;

Burn wounds are the most destructive and complicated type of skin or underlying soft tissue injury that are exacerbated by a prolonged inflammatory response. Several cell-based therapeutic systems through the culturing of potent stem cells on modified scaff ...

Article GUID: 38364284


Focused ultrasound-assisted delivery of immunomodulating agents in brain cancer

Author(s): Memari E; Khan D; Alkins R; Helfield B;

Focused ultrasound (FUS) combined with intravascularly circulating microbubbles can transiently increase the permeability of the blood-brain barrier (BBB) to enable targeted therapeutic delivery to the brain, the clinical testing of which is currently under ...

Article GUID: 38266715


A Systematic Evaluation of Curcumin Concentrations and Blue Light Parameters towards Antimicrobial Photodynamic Therapy against Cariogenic Microorganisms

Author(s): Comeau P; Manso A;

Dental caries is a highly preventable and costly disease. Unfortunately, the current management strategies are inadequate at reducing the incidence and new minimally invasive strategies are needed. In this study, a systematic evaluation of specific light pa ...

Article GUID: 38140048


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