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em In silico /em rational investigation of C-terminal arginine-containing white Lupin ( em Lupinus albus /em ) protein-derived peptides as arginase inhibitors

Author(s): Chukwuejim S; Fatoki TH; Aluko RE;

Arginase is a binuclear manganese metalloenzyme that modulates L-arginine availability and downstream metabolic pathways. It was hypothesized that C-terminal arginine-containing peptides generated through simulated gastrointestinal digestion of white lupin (Lupinus albus) proteins would exhibit arginase inhibitory activity. To test this hypothesis, integr ...

Article GUID: 42232067


Virtual screening, docking, and dynamics of potential new inhibitors of dihydrofolate reductase from Yersinia pestis.

Author(s): Bastos Lda C, de Souza FR, Guimarães AP, Sirouspour M, Cuya Guizado TR, Forgione P, Ramalho TC, França TC

J Biomol Struct Dyn. 2016 Oct;34(10):2184-98 Authors: Bastos Lda C, de Souza FR, Guimarães AP, Sirouspour M, Cuya Guizado TR, Forgione P, Ramalho TC, França TC

Article GUID: 26494420


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