Keyword search (4,163 papers available)

"Brugiapaglia S" Authored Publications:

Title Authors PubMed ID
1 Development and Application of Children s Sex- and Age-Specific Fat-Mass and Muscle-Mass Reference Curves From Dual-Energy X-Ray Absorptiometry Data for Predicting Cardiometabolic Risk Saputra ST; Van Hulst A; Henderson M; Brugiapaglia S; Faustini C; Kakinami L; 40878792
SOH
2 Real-time motion detection using dynamic mode decomposition Mignacca M; Brugiapaglia S; Bramburger JJ; 40421310
MATHSTATS
3 Near-optimal learning of Banach-valued, high-dimensional functions via deep neural networks Adcock B; Brugiapaglia S; Dexter N; Moraga S; 39454372
MATHSTATS
4 Generalization limits of Graph Neural Networks in identity effects learning D' Inverno GA; Brugiapaglia S; Ravanelli M; 39426036
ENCS
5 Invariance, Encodings, and Generalization: Learning Identity Effects With Neural Networks Brugiapaglia S; Liu M; Tupper P; 35798322
MATHSTATS

 

Title:Development and Application of Children s Sex- and Age-Specific Fat-Mass and Muscle-Mass Reference Curves From Dual-Energy X-Ray Absorptiometry Data for Predicting Cardiometabolic Risk
Authors:Saputra STVan Hulst AHenderson MBrugiapaglia SFaustini CKakinami L
Link:https://pubmed.ncbi.nlm.nih.gov/40878792/
DOI:10.1111/ijpo.70051
Publication:Pediatric obesity
Keywords:adipositycardiometabolic riskdual‐energy x‐ray absorptiometryreference curvesyouth
PMID:40878792 Category: Date Added:2025-08-29
Dept Affiliation: SOH
1 Department of Mathematics and Statistics, Concordia University, Quebec, Canada.
2 Ingram School of Nursing, McGill University, Quebec, Canada.
3 Centre de Recherche CHU Sainte-Justine, Université de Montréal, Quebec, Canada.
4 Department of Pediatrics, Université de Montréal, Quebec, Canada.
5 School of Public Health, Department of Social and Preventive Medicine, Université de Montréal, Montréal, Quebec, Canada.
6 School of Health, Concordia University, Quebec, Canada.

Description:

Background: A dual-energy x-ray absorptiometry (DXA)-derived phenotype classification based on fat mass and muscle mass has been developed for adults. We extended this to a paediatric population.

Methods: Children's (= 17 years) DXA data in NHANES (n = 6120) were used to generate sex- and age-specific deciles of appendicular skeletal muscle mass index and fat mass index with the Lambda Mu Sigma method. Four phenotypes (high [H] or low [L], adiposity [A] and muscle mass [M]: HA-HM, HA-LM, LA-HM, LA-LM) were identified based on being above/below the median compared to same-sex and same-age peers. These reference curves were applied to the QUALITY cohort (n = 630, 8-10 years of age in 2005) to assess whether the phenotypes correctly identified cardiometabolic risk at baseline, follow-up (2008-2010), and their longitudinal changes. Multiple linear regression models were adjusted for age, sex, and Tanner's stage.

Results: Compared to the LA-HM reference group, the HA-HM phenotype was associated with less favourable HDL, triglycerides, and HOMA-IR at baseline and first follow-up, but not in their changes. The HA-LM phenotype was associated with less favourable HOMA-IR at baseline and first follow-up.

Conclusions: Results suggest that phenotypes based on fat and muscle mass may have clinical utility in children and should be further investigated.





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