BookR: School of Health Core Facilities Booking
PubMed Publications| Keyword search (4,163 papers available) |  |
"Cai Z" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Hemodynamic correlates of fluctuations in neuronal excitability: A simultaneous Paired Associative Stimulation (PAS) and functional near infra-red spectroscopy (fNIRS) study | Cai Z; Pellegrino G; Spilkin A; Delaire E; Uji M; Abdallah C; Lina JM; Fecteau S; Grova C; | 40567300 PERFORM |
| 2 | NIRSTORM: a Brainstorm extension dedicated to functional near-infrared spectroscopy data analysis, advanced 3D reconstructions, and optimal probe design | Delaire É; Vincent T; Cai Z; Machado A; Hugueville L; Schwartz D; Tadel F; Cassani R; Bherer L; Lina JM; Pélégrini-Issac M; Grova C; | 40375973 SOH |
| 3 | Combating childhood overweight and obesity: The role of Olympic Movement and bodily movement | Tam BT; Wan K; Santosa S; Cai Z; | 39991475 SOH |
| 4 | Alzheimer's Imaging Consortium | Soucy JP; Belasso CJ; Cai Z; Bezgin G; Stevenson J; Rahmouni N; Tissot C; Lussier FZ; Rosa-Neto P; Rivaz HJ; Benali H; | 39782975 CONCORDIA |
| 5 | Biomarkers | Soucy JP; Belasso CJ; Cai Z; Bezgin G; Stevenson J; Rahmouni N; Tissot C; Lussier FZ; Rosa-Neto P; Rivaz HJ; Benali H; | 39784152 CONCORDIA |
| 6 | EEG/MEG source imaging of deep brain activity within the maximum entropy on the mean framework: Simulations and validation in epilepsy | Afnan J; Cai Z; Lina JM; Abdallah C; Delaire E; Avigdor T; Ros V; Hedrich T; von Ellenrieder N; Kobayashi E; Frauscher B; Gotman J; Grova C; | 38994740 SOH |
| 7 | Consistency of electrical source imaging in presurgical evaluation of epilepsy across different vigilance states | Avigdor T; Abdallah C; Afnan J; Cai Z; Rammal S; Grova C; Frauscher B; | 38217279 PERFORM |
| 8 | Bayesian workflow for the investigation of hierarchical classification models from tau-PET and structural MRI data across the Alzheimer's disease spectrum | Belasso CJ; Cai Z; Bezgin G; Pascoal T; Stevenson J; Rahmouni N; Tissot C; Lussier F; Rosa-Neto P; Soucy JP; Rivaz H; Benali H; | 37920382 PERFORM |
| 9 | Validating MEG source imaging of resting state oscillatory patterns with an intracranial EEG atlas | Afnan J; von Ellenrieder N; Lina JM; Pellegrino G; Arcara G; Cai Z; Hedrich T; Abdallah C; Khajehpour H; Frauscher B; Gotman J; Grova C; | 37149236 PERFORM |
| 10 | Hierarchical Bayesian modeling of the relationship between task-related hemodynamic responses and cortical excitability | Cai Z; Pellegrino G; Lina JM; Benali H; Grova C; | 36250709 PERFORM |
| 11 | Evaluation of a personalized functional near infra-red optical tomography workflow using maximum entropy on the mean | Cai Z; Uji M; Aydin Ü; Pellegrino G; Spilkin A; Delaire É; Abdallah C; Lina JM; Grova C; | 34342073 PERFORM |
| 12 | Deconvolution of hemodynamic responses along the cortical surface using personalized functional near infrared spectroscopy | Machado A; Cai Z; Vincent T; Pellegrino G; Lina JM; Kobayashi E; Grova C; | 33727581 PERFORM |
| 13 | The movement time analyser task investigated with functional near infrared spectroscopy: an ecologic approach for measuring hemodynamic response in the motor system. | Vasta R, Cerasa A, Gramigna V, Augimeri A, Olivadese G, Pellegrino G, Martino I, Machado A, Cai Z, Caracciolo M, Grova C, Quattrone A | 27055849 PERFORM |
| 14 | Optimal positioning of optodes on the scalp for personalized functional near-infrared spectroscopy investigations. | Machado A, Cai Z, Pellegrino G, Marcotte O, Vincent T, Lina JM, Kobayashi E, Grova C | 30107210 PERFORM |
| Title: | Hemodynamic correlates of fluctuations in neuronal excitability: A simultaneous Paired Associative Stimulation (PAS) and functional near infra-red spectroscopy (fNIRS) study | ||||
| Authors: | Cai Z, Pellegrino G, Spilkin A, Delaire E, Uji M, Abdallah C, Lina JM, Fecteau S, Grova C | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/40567300/ | ||||
| DOI: | 10.1016/j.ynirp.2022.100099 | ||||
| Publication: | Neuroimage. Reports | ||||
| Keywords: | Excitability; Finger tapping; Functional near infrared spectroscopy (fNIRS); Maximum entropy on the mean (MEM); Paired associative stimulation (PAS); Transcranial magnetic stimulation (TMS); | ||||
| PMID: | 40567300 | Category: | Date Added: | 2025-06-26 | |
| Dept Affiliation: |
PERFORM
1 Multimodal Functional Imaging Lab, Department of Physics and PERFORM Centre, Concordia University, Montréal, Québec, Canada. 2 Neurology and Neurosurgery Department, Montreal Neurological Institute, McGill University, Montréal, Québec, Canada. 3 Multimodal Functional Imaging Lab, Biomedical Engineering Department, McGill University, Montréal, Québec, Canada. 4 Département de Génie Electrique, École de Technologie Supérieure, Montréal, Québec, Canada. 5 Centre De Recherches En Mathématiques, Montréal, Québec, Canada. 6 CERVO Brain Research Centre, Centre Intégré Universitaire De Santé Et De Services Sociaux De La Capitale-Nationale, Canada. 7 Department of Psychiatry and Neurosciences, Faculty of Medicine, Université Laval, Canada. |
||||
Description: |
Background: The relationship between task-related hemodynamic activity and brain excitability is poorly understood in humans as it is technically challenging to combine simultaneously non-invasive brain stimulation and neuroimaging modalities. Cortical excitability corresponds to the readiness to become active and as such it may be linked to metabolic demand. Hypotheses: Cortical excitability and hemodynamic activity are positively linked so that increases in hemodynamic activity correspond to increases in excitability and vice-versa. Methods: Magnitudes of excitability and hemodynamic activity were investigated via simultaneous Transcranial Magnetic Stimulation (TMS) and functional Near Infrared Spectroscopy (fNIRS). Sixteen healthy subjects participated in a sham-controlled, pseudorandomized, counterbalanced study with PAS (PAS10/PAS25/Sham) on the right primary motor cortex (M1). The relationship between M1 excitability (Motor Evoked Potentials, MEP) and hemodynamic responses to finger tapping reconstructed via personalized fNIRS was assessed. Results: Hemodynamic activity exhibited a significant correlation with cortical excitability: increased HbO and HbR (absolute amplitude) corresponded to increased excitability and vice-versa (r = 0.25; p = 0.03 and r = 0.16; p = 0.17, respectively). The effect of PAS on excitability and hemodynamic activity showed a trend of positive correlation with MEP ratios (post-PAS/pre-PAS) linked to HbO and HbR ratios (r = 0.19, p = 0.29; r = 0.18, p = 0.30, respectively). Conclusions: TMS-fNIRS is a suitable technique for simultaneous investigation of excitability and hemodynamic responses and indicates a relationship between these two cortical properties. PAS effect is not limited to cortical excitability but also impacts hemodynamic processes. These findings have an impact on the application of neuromodulatory interventions in patients with neuropsychiatric disorders. |
