Keyword search (4,163 papers available)

"Chaudhri N" Authored Publications:

Title Authors PubMed ID
1 Augmenting glutamatergic, but not dopaminergic, activity in the nucleus accumbens shell disrupts responding to a discrete alcohol cue in an alcohol context Valyear MD; Brown A; Deyab G; Villaruel FR; Lahlou S; Caporicci-Dinucci N; Chaudhri N; 38185906
PSYCHOLOGY
2 Neural correlates of recall and extinction in a rat model of appetitive Pavlovian conditioning Brown A; Villaruel FR; Chaudhri N; 36496079
PSYCHOLOGY
3 Optogenetic stimulation of infralimbic cortex projections to the paraventricular thalamus attenuates context-induced renewal Brown A; Chaudhri N; 36373226
PSYCHOLOGY
4 Learning processes in relapse to alcohol use: lessons from animal models Valyear MD; LeCocq MR; Brown A; Villaruel FR; Segal D; Chaudhri N; 36264342
PSYCHOLOGY
5 Supplementary dataset of context-dependent conditioned responding to an alcohol-predictive cue in female and male rats Segal D; Valyear MD; Chaudhri N; 35330738
PSYCHOLOGY
6 Corticostriatal suppression of appetitive Pavlovian conditioned responding Villaruel FR; Martins M; Chaudhri N; 34880119
PSYCHOLOGY
7 The Role of Context Conditioning in the Reinstatement of Responding to an Alcohol-Predictive Conditioned Stimulus LeCocq MR; Sun S; Chaudhri N; 34852244
PSYCHOLOGY
8 The role of context on responding to an alcohol-predictive cue in female and male rats Segal D; Valyear MD; Chaudhri N; 34742865
PSYCHOLOGY
9 Cue-alcohol associative learning in female rats. Cofresí RU, Monfils MH, Chaudhri N, Gonzales RA, Lee HJ 31002878
PSYCHOLOGY
10 Dissociable mesolimbic dopamine circuits control responding triggered by alcohol-predictive discrete cues and contexts. Valyear MD, Glovaci I, Zaari A, Lahlou S, Trujillo-Pisanty I, Andrew Chapman C, Chaudhri N 32724058
PSYCHOLOGY
11 Comparing ABA, AAB, and ABC Renewal of Appetitive Pavlovian Conditioned Responding in Alcohol- and Sucrose-Trained Male Rats. Khoo SY, Sciascia JM, Brown A, Chaudhri N 32116588
PSYCHOLOGY
12 Context controls the timing of responses to an alcohol-predictive conditioned stimulus. Valyear MD, Chaudhri N 32017964
PSYCHOLOGY
13 Considering Drug-Associated Contexts in Substance Use Disorders and Treatment Development. LeCocq MR, Randall PA, Besheer J, Chaudhri N 31898285
CSBN
14 Alcohol-associated antecedent stimuli elicit alcohol seeking in non-dependent rats and may activate the insula. Cofresí RU, Grote DJ, Le EVT, Monfils MH, Chaudhri N, Gonzales RA, Lee HJ 30612041
PSYCHOLOGY
15 The medial prefrontal cortex is required for responding to alcohol-predictive cues but only in the absence of alcohol delivery. Khoo SY, Sciascia JM, Pettorelli A, Maddux JN, Chaudhri N 31070082
PSYCHOLOGY
16 Vendor differences in alcohol consumption and the contribution of dopamine receptors to Pavlovian-conditioned alcohol-seeking in Long-Evans rats. Sparks LM, Sciascia JM, Ayorech Z, Chaudhri N 24096535
PSYCHOLOGY
17 The attribution of incentive salience to Pavlovian alcohol cues: a shift from goal-tracking to sign-tracking. Srey CS, Maddux JM, Chaudhri N 25784867
CSBN
18 Alcohol-Seeking Triggered by Discrete Pavlovian Cues is Invigorated by Alcohol Contexts and Mediated by Glutamate Signaling in the Basolateral Amygdala. Sciascia JM, Reese RM, Janak PH, Chaudhri N 25953360
PSYCHOLOGY
19 Robust optical fiber patch-cords for in vivo optogenetic experiments in rats. Trujillo-Pisanty I, Sanio C, Chaudhri N, Shizgal P 26150997
CSBN
20 Varenicline Reduces Context-Induced Relapse to Alcohol-Seeking through Actions in the Nucleus Accumbens. Lacroix F, Pettorelli A, Maddux JN, Heidari-Jam A, Chaudhri N 27834390
PSYCHOLOGY
21 Nicotine-induced enhancement of Pavlovian alcohol-seeking behavior in rats. Maddux JN, Chaudhri N 28011981
CSBN
22 Individual Differences in the Attribution of Incentive Salience to a Pavlovian Alcohol Cue. Villaruel FR, Chaudhri N 28082877
PSYCHOLOGY
23 Postretrieval Extinction Attenuates Alcohol Cue Reactivity in Rats. Cofresí RU, Lewis SM, Chaudhri N, Lee HJ, Monfils MH, Gonzales RA 28169439
CSBN
24 Alcohol-seeking and relapse: A focus on incentive salience and contextual conditioning. Valyear MD, Villaruel FR, Chaudhri N 28473252
PSYCHOLOGY
25 Optogenetic Activation of the Infralimbic Cortex Suppresses the Return of Appetitive Pavlovian-Conditioned Responding Following Extinction. Villaruel FR, Lacroix F, Sanio C, Sparks DW, Chapman CA, Chaudhri N 29045570
PSYCHOLOGY
26 Characterizing conditioned reactivity to sequential alcohol-predictive cues in well-trained rats. Cofresí RU, Lee HJ, Monfils MH, Chaudhri N, Gonzales RA 29635111
PSYCHOLOGY
27 Modeling Relapse to Pavlovian Alcohol-Seeking in Rats Using Reinstatement and Spontaneous Recovery Paradigms. LeCocq MR, Lahlou S, Chahine M, Padillo LN, Chaudhri N 29969151
CSBN
28 Context and topography determine the role of basolateral amygdala metabotropic glutamate receptor 5 in appetitive Pavlovian responding. Khoo SY, LeCocq MR, Deyab GE, Chaudhri N 30758331
PSYCHOLOGY

 

Title:Alcohol-Seeking Triggered by Discrete Pavlovian Cues is Invigorated by Alcohol Contexts and Mediated by Glutamate Signaling in the Basolateral Amygdala.
Authors:Sciascia JM,  Reese RM,  Janak PH,  Chaudhri N
Link:https://www.ncbi.nlm.nih.gov/pubmed/25953360?dopt=Abstract
Publication:
Keywords:
PMID:25953360 Category:Neuropsychopharmacology Date Added:2019-05-31
Dept Affiliation: PSYCHOLOGY
1 Center for Studies in Behavioral Neurobiology/FRQS Groupe de Recherche en Neurobiologie Comportementale, Department of Psychology, Concordia University, Montreal, QC, Canada.
2 Departments of Psychological and Brain Sciences and Neuroscience, Johns Hopkins University, Baltimore, MD, USA.

Description:

Alcohol-Seeking Triggered by Discrete Pavlovian Cues is Invigorated by Alcohol Contexts and Mediated by Glutamate Signaling in the Basolateral Amygdala.

Neuropsychopharmacology. 2015 Nov;40(12):2801-12

Authors: Sciascia JM, Reese RM, Janak PH, Chaudhri N

Abstract

The environmental context in which a discrete Pavlovian conditioned stimulus (CS) is experienced can profoundly impact conditioned responding elicited by the CS. We hypothesized that alcohol-seeking behavior elicited by a discrete CS that predicted alcohol would be influenced by context and require glutamate signaling in the basolateral amygdala (BLA). Male, Long-Evans rats were allowed to drink 15% ethanol (v/v) until consumption stabilized. Next, rats received Pavlovian conditioning sessions in which a 10?s CS (15 trials/session) was paired with ethanol (0.2?ml/CS). Entries into a port where ethanol was delivered were measured. Pavlovian conditioning occurred in a specific context (alcohol context) and was alternated with sessions in a different context (non-alcohol context) where neither the CS nor ethanol was presented. At test, the CS was presented without ethanol in the alcohol context or the non-alcohol context, following a bilateral microinfusion (0.3?µl/hemisphere) of saline or the AMPA glutamate receptor antagonist NBQX (2,3-dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt) in the BLA (0, 0.3, or 1.0?µg/0.3?µl). The effect of NBQX (0, 0.3?µg/0.3?µl) in the caudate putamen (CPu) on CS responding in the non-alcohol context was also tested. The discrete alcohol CS triggered more alcohol-seeking behavior in the alcohol context than the non-alcohol context. NBQX in the BLA reduced CS responding in both contexts but had no effect in the CPu. These data indicate that AMPA glutamate receptors in the BLA are critical for alcohol-seeking elicited by a discrete CS and that behavior triggered by the CS is strongly invigorated by an alcohol context.

PMID: 25953360 [PubMed - indexed for MEDLINE]




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